Comparison of effectiveness of carvedilol versus metoprolol or atenolol for atrial fibrillation appearing after coronary artery bypass grafting or cardiac valve operation

• Published in: The American journal of cardiology Vol. 92; no. 6; pp. 735 - 736
• Main Authors: Merritt, J.Christopher, Niebauer, Mark, Tarakji, Khaldoun, Hammer, Donald, Mills, Roger M.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 15.09.2003; Elsevier; Elsevier Limited
• Subjects: Adult; Aged; Anti-Arrhythmia Agents - therapeutic use; Antiarythmic agents; Atenolol - therapeutic use; Atrial Fibrillation - etiology; Atrial Fibrillation - prevention & control; Biological and medical sciences; Carbazoles - therapeutic use; Cardiac arrhythmia; Cardiovascular system; Carvedilol; Coronary Artery Bypass - adverse effects; Coronary Artery Disease - surgery; Female; Heart surgery; Heart Valve Diseases - surgery; Heart Valve Prosthesis Implantation - adverse effects; Humans; Male; Medical sciences; Metoprolol - therapeutic use; Middle Aged; Outcome Assessment (Health Care); Pharmacology. Drug treatments; Postoperative Complications; Prevention; Propanolamines - therapeutic use; Retrospective Studies; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the heart; Vasodilator Agents - therapeutic use; Vasodilator agent; Arrhythmia; α1-Adrenergic receptor; Cardiovascular disease; β2-Adrenergic receptor; Heart valve; Alpha blocking agent; β1-Adrenergic receptor; Aortocoronary; Heart disease; Surgery; Complication; Graft; Antagonist; Human; Metoprolol; Treatment efficiency; Atrial fibrillation; Antiarrhythmic agent; Atenolol; Excitability disorder; Chemotherapy; Treatment; Bypass; Carvedilol; Comparative study; Beta blocking agent

A retrospective review of 115 patients who underwent cardiac surgery demonstrated a marked reduction in postoperative atrial fibrillation (8% vs 32%, p <0.05) in patients who received carvedilol versus metoprolol or atenolol immediately after surgery. A prospective study examining the possibility...