The inverse problem in mathematical biology

• Published in: Mathematical biosciences Vol. 260; pp. 11 - 15
• Main Authors: Clermont, Gilles, Zenker, Sven
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2015
• Subjects: Biological systems; Ensemble models; Humans; Inverse problem; Models, Biological; Models, Theoretical; Parameter estimation; Ensemble models; Parameter estimation; Biological systems; Inverse problem

Biological systems present particular challengers to model for the purposes of formulating predictions of generating biological insight. These systems are typically multi-scale, complex, and empirical observations are often sparse and subject to variability and uncertainty. This manuscript will revi...