A closed-loop human simulator for investigating the role of feedback control in brain-machine interfaces

• Published in: Journal of neurophysiology Vol. 105; no. 4; pp. 1932 - 1949
• Main Authors: Cunningham, John P., Nuyujukian, Paul, Gilja, Vikash, Chestek, Cindy A., Ryu, Stephen I., Shenoy, Krishna V.
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.04.2011
• Subjects: Adult; Algorithms; Animals; Computers; Electric Stimulation; Feedback; Humans; Innovative Methodology; Macaca mulatta; Male; Models, Animal; Neural Prostheses; Software; User-Computer Interface

Neural prosthetic systems seek to improve the lives of severely disabled people by decoding neural activity into useful behavioral commands. These systems and their decoding algorithms are typically developed “offline,” using neural activity previously gathered from a healthy animal, and the decoded...