Newborn Screening for Biliary Atresia
Biliary atresia is the most common cause of pediatric end-stage liver disease and the leading indication for pediatric liver transplantation. Affected infants exhibit evidence of biliary obstruction within the first few weeks after birth. Early diagnosis and successful surgical drainage of bile are...
Saved in:
Published in | Pediatrics (Evanston) Vol. 136; no. 6; p. e1663 |
---|---|
Main Author | |
Format | Journal Article |
Language | English |
Published |
United States
01.12.2015
|
Subjects | |
Online Access | Get more information |
Cover
Loading…
Abstract | Biliary atresia is the most common cause of pediatric end-stage liver disease and the leading indication for pediatric liver transplantation. Affected infants exhibit evidence of biliary obstruction within the first few weeks after birth. Early diagnosis and successful surgical drainage of bile are associated with greater survival with the child's native liver. Unfortunately, because noncholestatic jaundice is extremely common in early infancy, it is difficult to identify the rare infant with cholestatic jaundice who has biliary atresia. Hence, the need for timely diagnosis of this disease warrants a discussion of the feasibility of screening for biliary atresia to improve outcomes. Herein, newborn screening for biliary atresia in the United States is assessed by using criteria established by the Discretionary Advisory Committee on Heritable Disorders in Newborns and Children. Published analyses indicate that newborn screening for biliary atresia by using serum bilirubin concentrations or stool color cards is potentially life-saving and cost-effective. Further studies are necessary to evaluate the feasibility, effectiveness, and costs of potential screening strategies for early identification of biliary atresia in the United States. |
---|---|
AbstractList | Biliary atresia is the most common cause of pediatric end-stage liver disease and the leading indication for pediatric liver transplantation. Affected infants exhibit evidence of biliary obstruction within the first few weeks after birth. Early diagnosis and successful surgical drainage of bile are associated with greater survival with the child's native liver. Unfortunately, because noncholestatic jaundice is extremely common in early infancy, it is difficult to identify the rare infant with cholestatic jaundice who has biliary atresia. Hence, the need for timely diagnosis of this disease warrants a discussion of the feasibility of screening for biliary atresia to improve outcomes. Herein, newborn screening for biliary atresia in the United States is assessed by using criteria established by the Discretionary Advisory Committee on Heritable Disorders in Newborns and Children. Published analyses indicate that newborn screening for biliary atresia by using serum bilirubin concentrations or stool color cards is potentially life-saving and cost-effective. Further studies are necessary to evaluate the feasibility, effectiveness, and costs of potential screening strategies for early identification of biliary atresia in the United States. |
Author | Wang, Kasper S |
Author_xml | – sequence: 1 givenname: Kasper S surname: Wang fullname: Wang, Kasper S |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/26620065$$D View this record in MEDLINE/PubMed |
BookMark | eNo1jktLAzEURoMo9qFblzIbl6l53UyyrKXaQtGFui553MhImxmSivjvrair83EWH2dCTnOfkZArzmYclLgdMNaZYByohJadkDFn1lAlWhiRSa3vjDEFrTgnI6G1YEzDmNw84qfvS26eQ0HMXX5rUl-au27XufLVzA8Fa-cuyFlyu4qXf5yS1_vly2JFN08P68V8Q4My6kBVFNJpzkLyAEFoCcrBcStIMThnbIs2WO9-jATjeVJGeuRW2tiitmJKrn9_hw-_x7gdSrc_Zmz_e8U3cqpBCQ |
CitedBy_id | crossref_primary_10_1001_jamanetworkopen_2019_13321 crossref_primary_10_1097_PG9_0000000000000345 crossref_primary_10_1007_s00535_023_02051_1 crossref_primary_10_1016_j_jpedsurg_2017_08_048 crossref_primary_10_1016_j_nurpra_2022_02_015 crossref_primary_10_1007_s12098_017_2342_0 crossref_primary_10_1097_MPG_0000000000003701 crossref_primary_10_1186_s12887_023_04370_x crossref_primary_10_1097_MPG_0000000000001887 crossref_primary_10_1016_j_jpeds_2022_09_028 crossref_primary_10_1007_s12262_021_03107_3 crossref_primary_10_1542_gr_38_4_40 crossref_primary_10_1007_s00383_017_4146_8 crossref_primary_10_1097_MPG_0000000000001950 crossref_primary_10_1097_MPG_0000000000002489 crossref_primary_10_56712_latam_v4i1_383 crossref_primary_10_1001_jama_2020_0837 crossref_primary_10_1111_ijcp_13860 crossref_primary_10_1542_peds_2021_053073 crossref_primary_10_1155_2019_9036362 crossref_primary_10_1136_archdischild_2019_317787 crossref_primary_10_1039_C8NJ03575J crossref_primary_10_12688_f1000research_125555_1 crossref_primary_10_1097_PAF_0000000000000511 crossref_primary_10_1016_j_jpeds_2019_05_048 crossref_primary_10_1007_s00383_017_4156_6 crossref_primary_10_1542_peds_2022_058859 crossref_primary_10_1016_j_jpeds_2017_05_006 crossref_primary_10_1002_cld_1165 crossref_primary_10_1038_s41575_019_0132_z crossref_primary_10_1055_s_0039_1698764 crossref_primary_10_1002_jcla_24995 crossref_primary_10_1016_j_sempedsurg_2020_150950 crossref_primary_10_1016_j_pcl_2017_11_013 crossref_primary_10_1056_NEJMc1601230 crossref_primary_10_1002_cld_843 crossref_primary_10_1016_j_jpedsurg_2019_01_008 crossref_primary_10_1097_MOP_0000000000000414 crossref_primary_10_1111_odi_12827 crossref_primary_10_1016_j_liver_2024_100216 crossref_primary_10_1373_clinchem_2016_268532 crossref_primary_10_1177_2333794X19829757 crossref_primary_10_1007_s00431_022_04612_7 crossref_primary_10_1007_s12072_020_10070_w crossref_primary_10_1007_s00383_017_4175_3 crossref_primary_10_1016_j_jpedsurg_2021_02_027 crossref_primary_10_1007_s00431_021_04176_y crossref_primary_10_1097_MPG_0000000000002582 crossref_primary_10_1097_PAI_0000000000000638 crossref_primary_10_15342_ijms_2023_717 crossref_primary_10_1016_j_cnc_2022_04_002 |
ContentType | Journal Article |
Contributor | Fallat, Mary Elizabeth Sokol, Ronald J Stewart, Dan L Mogul, Douglas B Cummings, James J Goldberg, James Davidoff, Andrew Moss, R Lawrence Couto, Jim Schwarz, Kathleen B Aucott, Susan Karpen, Saul J Caty, Michael G Meyers, Rebecka L Keels, Erin L Wang, Kasper S Puopolo, Karen Heiss, Kurt F Barfield, Wanda D Eichenwald, Eric C Watterberg, Kristi L Benitz, William E Holcomb, 3rd, George Raju, Tonse N K Harpavat, Sanjiv Lacaze, Thierry Goldsmith, Jay Poindexter, Brenda B Thorne, Vivian Kerkar, Nanda |
Contributor_xml | – sequence: 1 givenname: R Lawrence surname: Moss fullname: Moss, R Lawrence – sequence: 2 givenname: Michael G surname: Caty fullname: Caty, Michael G – sequence: 3 givenname: Andrew surname: Davidoff fullname: Davidoff, Andrew – sequence: 4 givenname: Mary Elizabeth surname: Fallat fullname: Fallat, Mary Elizabeth – sequence: 5 givenname: Kurt F surname: Heiss fullname: Heiss, Kurt F – sequence: 6 givenname: George surname: Holcomb, 3rd fullname: Holcomb, 3rd, George – sequence: 7 givenname: Rebecka L surname: Meyers fullname: Meyers, Rebecka L – sequence: 8 givenname: Vivian surname: Thorne fullname: Thorne, Vivian – sequence: 9 givenname: Kristi L surname: Watterberg fullname: Watterberg, Kristi L – sequence: 10 givenname: Susan surname: Aucott fullname: Aucott, Susan – sequence: 11 givenname: William E surname: Benitz fullname: Benitz, William E – sequence: 12 givenname: James J surname: Cummings fullname: Cummings, James J – sequence: 13 givenname: Eric C surname: Eichenwald fullname: Eichenwald, Eric C – sequence: 14 givenname: Jay surname: Goldsmith fullname: Goldsmith, Jay – sequence: 15 givenname: Brenda B surname: Poindexter fullname: Poindexter, Brenda B – sequence: 16 givenname: Karen surname: Puopolo fullname: Puopolo, Karen – sequence: 17 givenname: Dan L surname: Stewart fullname: Stewart, Dan L – sequence: 18 givenname: Kasper S surname: Wang fullname: Wang, Kasper S – sequence: 19 givenname: Wanda D surname: Barfield fullname: Barfield, Wanda D – sequence: 20 givenname: James surname: Goldberg fullname: Goldberg, James – sequence: 21 givenname: Thierry surname: Lacaze fullname: Lacaze, Thierry – sequence: 22 givenname: Erin L surname: Keels fullname: Keels, Erin L – sequence: 23 givenname: Tonse N K surname: Raju fullname: Raju, Tonse N K – sequence: 24 givenname: Jim surname: Couto fullname: Couto, Jim – sequence: 25 givenname: Nanda surname: Kerkar fullname: Kerkar, Nanda – sequence: 26 givenname: Saul J surname: Karpen fullname: Karpen, Saul J – sequence: 27 givenname: Ronald J surname: Sokol fullname: Sokol, Ronald J – sequence: 28 givenname: Kathleen B surname: Schwarz fullname: Schwarz, Kathleen B – sequence: 29 givenname: Douglas B surname: Mogul fullname: Mogul, Douglas B – sequence: 30 givenname: Sanjiv surname: Harpavat fullname: Harpavat, Sanjiv |
Copyright | Copyright © 2015 by the American Academy of Pediatrics. |
Copyright_xml | – notice: Copyright © 2015 by the American Academy of Pediatrics. |
CorporateAuthor | Committee on Fetus and Newborn Childhood Liver Disease Research Network Section on Surgery |
CorporateAuthor_xml | – name: Section on Surgery – name: Committee on Fetus and Newborn – name: Childhood Liver Disease Research Network |
DBID | CGR CUY CVF ECM EIF NPM |
DOI | 10.1542/peds.2015-3570 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) |
DatabaseTitleList | MEDLINE |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | no_fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 1098-4275 |
ExternalDocumentID | 26620065 |
Genre | Journal Article |
GeographicLocations | United States |
GeographicLocations_xml | – name: United States |
GrantInformation_xml | – fundername: NIDDK NIH HHS grantid: U01 DK084538 |
GroupedDBID | --- -ET ..I .55 .GJ 0R~ 123 18M 1CY 1HT 26- 29O 2KS 2QL 2WC 36B 39C 4.4 41~ 53G 5RE 5VS 6PF 7K8 85S 8F7 8GL 96U AAAMJ AAHTB AAIKC AAJMC AAKAS AAMNW AAQOH AAWTL AAWTO AAYOK ABCZD ABIVO ABJNI ABOCM ABPEJ ABPPZ ACBMB ACGFO ACGOD ACNCT ACPRK ADCOW ADZCM AENEX AFAZI AFFNX AFHKK AFOSN AFRAH AGFXO AHMBA AJUXI ALMA_UNASSIGNED_HOLDINGS BKOMP CGR CS3 CUY CVF DIK DU5 E3Z EBS ECM EIF EJD ESX EX3 F5P F8P FEDTE GICCO GOZPB GX1 H13 HF~ HVGLF IAG IAO ICJ IEA IER IGG IHR IHW IMI INH INR IOF IPO IPY ISE ITC IVC KO8 KQ8 L7B LXL LXN LXY N4W N9A NEJ NPM OHT OK1 OMK OVD P0W P2P PDE PQQKQ Q.- RHF RHI SJN TAE TEORI TR2 TWZ UBE UHB UMD W8F WH7 WHG WOQ WOW WQ9 X7M XJT XOL XZL YCJ YHG YHZ YOC YQI YQJ YZZ ZGI ZRR ZXP ~KM ~X8 |
ID | FETCH-LOGICAL-c484t-4d23a610cfb55c26354a5fb545fdcaa897e9c9bab545358b1f483be1939d7e692 |
IngestDate | Sat Sep 28 08:00:38 EDT 2024 |
IsDoiOpenAccess | false |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 6 |
Language | English |
License | Copyright © 2015 by the American Academy of Pediatrics. |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-c484t-4d23a610cfb55c26354a5fb545fdcaa897e9c9bab545358b1f483be1939d7e692 |
OpenAccessLink | https://pediatrics.aappublications.org/content/pediatrics/136/6/e1663.full.pdf |
PMID | 26620065 |
ParticipantIDs | pubmed_primary_26620065 |
PublicationCentury | 2000 |
PublicationDate | 2015-Dec |
PublicationDateYYYYMMDD | 2015-12-01 |
PublicationDate_xml | – month: 12 year: 2015 text: 2015-Dec |
PublicationDecade | 2010 |
PublicationPlace | United States |
PublicationPlace_xml | – name: United States |
PublicationTitle | Pediatrics (Evanston) |
PublicationTitleAlternate | Pediatrics |
PublicationYear | 2015 |
References | 12608882 - Paediatr Drugs. 2003;5(3):177-83 20154628 - Genet Med. 2010 Mar;12(3):153-9 12482154 - Am J Transplant. 2002 Nov;2(10):993-8 25681196 - J Pediatr. 2015 Apr;166(4):897-902.e1 21869674 - Ann Surg. 2011 Oct;254(4):577-85 25003372 - J Pediatr Gastroenterol Nutr. 2014 Nov;59(5):624-8 2329462 - J Pediatr Surg. 1990 Apr;25(4):442-5 19403492 - Pediatrics. 2009 May;123(5):1280-6 23703680 - Hepatology. 2013 Nov;58(5):1724-31 18376248 - J Pediatr Gastroenterol Nutr. 2008 Mar;46(3):299-307 19642116 - Liver Transpl. 2009 Aug;15(8):876-82 23907646 - Genet Med. 2014 Feb;16(2):183-7 12827000 - J Pediatr Gastroenterol Nutr. 2003 Jul;37(1):4-21 20223479 - J Pediatr. 2010 Jun;156(6):936-40, 940.e1 20154629 - Genet Med. 2010 Mar;12(3):131-4 14561261 - J Med Screen. 2003;10 (3):112-6 24373065 - J Paediatr Child Health. 2014 Mar;50(3):196-201 16872500 - Orphanet J Rare Dis. 2006 Jul 26;1:28 25221934 - J Pediatr Gastroenterol Nutr. 2015 Jan;60(1):91-8 22106076 - Pediatrics. 2011 Dec;128(6):e1428-33 15915488 - Liver Transpl. 2005 Jun;11(6):612-20 25009198 - J Med Screen. 2014 Sep;21(3):126-32 25015575 - J Pediatr. 2014 Sep;165(3):539-546.e2 17929308 - Hepatology. 2007 Nov;46(5):1632-8 16585309 - Pediatrics. 2006 Apr;117(4):1147-54 21140377 - Hepatology. 2011 Jan;53(1):202-8 |
References_xml | |
SSID | ssj0004572 |
Score | 2.466597 |
Snippet | Biliary atresia is the most common cause of pediatric end-stage liver disease and the leading indication for pediatric liver transplantation. Affected infants... |
SourceID | pubmed |
SourceType | Index Database |
StartPage | e1663 |
SubjectTerms | Biliary Atresia - diagnosis Cost-Benefit Analysis Early Diagnosis Humans Infant Infant, Newborn Neonatal Screening - methods United States |
Title | Newborn Screening for Biliary Atresia |
URI | https://www.ncbi.nlm.nih.gov/pubmed/26620065 |
Volume | 136 |
hasFullText | |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV09T8MwELUoSIgF8f2NMsBoUBI7sceCQBWonVrRrbIdW6oEpUMnfj13tpuGAuJjiSJbaRO_5OX1eveOkAsNL00nnaDclYay1BqqgQOpklicpk2WVljv3O0VnQF7GPLhogWnry6Z6Svz9mVdyX9QhTHAFatk_4Bs_aEwAPuAL2wBYdj-CmNgKIAQH1DMnpnnRN6Mn8eYC9fGMpCxasrPujGHj7V6Fe21Xx0NeIrh40eFDuIxLhqDAilvJFjYQGToE8qy0JWkZrrgNRIhbfKWTYvAM58YlTN0aJ3aCr3N4YtyHhp9NJZ3-uLXF171GJ_gP88uOVzPp1qkVQpsv9HDiEvt-F5m0WwTTuX644mglXM8eOlngZcH_S2yGXV90g4gbZMVO9kh692YubBLLiNWSY1VAlglEaskYrVHBvd3_dsOjS0qqGGCzSirslyBAjVOc27Q2IcpDvuMu8ooJWRppZFa4UjOhU4dE7m2oJplVdpCZvtkdfI6sYckqUSlgEAl_g_OCpEqUIbK5K7gBnhYuyNyEC5wNA0-JKP5pR9_O3NCNhZ3xylZc3Dj2zNQUTN97pf5HX6dF9Q |
link.rule.ids | 780 |
linkProvider | National Library of Medicine |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Newborn+Screening+for+Biliary+Atresia&rft.jtitle=Pediatrics+%28Evanston%29&rft.au=Wang%2C+Kasper+S&rft.date=2015-12-01&rft.eissn=1098-4275&rft.volume=136&rft.issue=6&rft.spage=e1663&rft_id=info:doi/10.1542%2Fpeds.2015-3570&rft_id=info%3Apmid%2F26620065&rft_id=info%3Apmid%2F26620065&rft.externalDocID=26620065 |