SARS-CoV-2-specific ELISA development

• Published in: Journal of immunological methods Vol. 484-485; p. 112832
• Main Authors: Roy, Vicky, Fischinger, Stephanie, Atyeo, Caroline, Slein, Matthew, Loos, Carolin, Balazs, Alejandro, Luedemann, Corinne, Astudillo, Michael Gerino, Yang, Diane, Wesemann, Duane R., Charles, Richelle, Lafrate, A. John, Feldman, Jared, Hauser, Blake, Caradonna, Tim, Miller, Tyler E., Murali, Mandakolathur R., Baden, Lindsey, Nilles, Eric, Ryan, Edward, Lauffenburger, Douglas, Beltran, Wilfredo Garcia, Alter, Galit
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2020; Published by Elsevier B.V
• Subjects: adaptive immunity; antibodies; Antibodies, Viral - blood; Antibodies, Viral - immunology; Antibodies, Viral - isolation & purification; Betacoronavirus - immunology; Betacoronavirus - isolation & purification; Clinical Laboratory Techniques - methods; Coronavirus Infections - blood; Coronavirus Infections - diagnosis; Coronavirus Infections - immunology; Coronavirus Infections - virology; COVID-19; COVID-19 infection; COVID-19 Testing; Enzyme-Linked Immunosorbent Assay; Feasibility Studies; genomics; High-Throughput Screening Assays; Humans; Pandemics; Pneumonia, Viral - blood; Pneumonia, Viral - diagnosis; Pneumonia, Viral - immunology; Pneumonia, Viral - virology; Reproducibility of Results; respiratory system; RNA; SARS-CoV-2; Sensitivity and Specificity; Severe acute respiratory syndrome coronavirus 2; Time Factors; viral shedding; virus replication; viruses

Critical to managing the spread of COVID-19 is the ability to diagnose infection and define the acquired immune response across the population. While genomic tests for the novel Several Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) detect the presence of viral RNA for a limited time frame, w...