β-Hemolysis May Not Be a Reliable Indicator of Leukotoxicity of Mannheimia haemolytica Isolates

• Published in: Toxins Vol. 10; no. 5; p. 173
• Main Authors: Bavananthasivam, Jegarubee, Shanthalingam, Sudarvili, Kugadas, Abirami, Raghavan, Bindu, Batra, Sai, Srikumaran, Subramaniam
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 25.04.2018; MDPI
• Subjects: Bronchopneumonia; Cytotoxicity; Deletion mutant; Enzyme-linked immunosorbent assay; Hemolysis; indicator; leukotoxicity; leukotoxin; Mannheimia haemolytica; Proteins; Toxicity; Virulence; Virulence factors; indicator; Mannheimia haemolytica; leukotoxin; hemolysis; leukotoxicity

Mannheimia (Pasteurella) haemolytica causes bronchopneumonia in domestic and wild ruminants. Leukotoxin is the critical virulence factor of M. haemolytica. Since β-hemolysis is caused by a large number of leukotoxin-positive M. haemolytica isolates, all β-hemolytic M. haemolytica isolates are consid...