Significance of the imidazoline receptors in toxicology

• Published in: Clinical toxicology (Philadelphia, Pa.) Vol. 52; no. 5; pp. 454 - 469
• Main Authors: Lowry, J. A., Brown, J. T.
• Format: Journal Article
• Language: English
• Published: England Informa Healthcare 01.06.2014; Taylor & Francis
• Subjects: Adrenergic alpha-2 Receptor Agonists - pharmacology; Adrenergic alpha-2 Receptor Agonists - poisoning; Animals; Clonidine; Clonidine - pharmacology; Clonidine - poisoning; Humans; Imidazoles - pharmacology; Imidazoles - poisoning; Imidazoline receptors; Imidazoline Receptors - agonists; Imidazoline Receptors - metabolism; Imidazolines - pharmacology; Imidazolines - poisoning; Tetrahydrozoline; Tetrahydrozoline; Clonidine; Imidazoline receptors

Abstract Introduction. The alpha-2 adrenergic (AA-2) receptor agonists and imidazolines are common exposures in the American Association of Poison Control Centers (AAPCC) National Poison Data System (NPDS). Although the interaction between the AA-2 receptor and imidazoline receptors has been extensi...