Nationwide Descriptive Epidemiological Study of Patients with COVID-19 Evacuated from Wuhan, China to Japan from January to February, 2020

We investigated the epidemiological findings regarding the route of coronavirus disease 2019 (COVID-19) and infection prevention and control (IPC) measures among returnees in the emergency evacuation from Wuhan, China to Japan during the COVID-19 outbreak in 2020. A total of 12 of the 14 returnees (...

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Published inJapanese Journal of Infectious Diseases Vol. 76; no. 1; pp. 20 - 26
Main Authors Nomoto, Hidetoshi, Ishikane, Masahiro, Gu, Yoshiaki, Yamamuro, Ryosuke, Osawa, Ryosuke, Hosokawa, Naoto, Sahara, Toshinori, Nakamura-Uchiyama, Fukumi, Fukushima, Kazuaki, Sekiya, Noritaka, Imamura, Akifumi, Fujikura, Yuji, Kawana, Akihiko, Nagata, Kaoru, Tamura, Kaku, Kutsuna, Satoshi, Ohmagari, Norio
Format Journal Article
LanguageEnglish
Published Japan National Institute of Infectious Diseases 31.01.2023
Japan Science and Technology Agency
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Abstract We investigated the epidemiological findings regarding the route of coronavirus disease 2019 (COVID-19) and infection prevention and control (IPC) measures among returnees in the emergency evacuation from Wuhan, China to Japan during the COVID-19 outbreak in 2020. A total of 12 of the 14 returnees (median age [range]: 49.5 years [29–65 years]; 9 men [75%]) had confirmed COVID-19. The proportion of returnees with COVID-19 was 12/566 (2.1%) in Flights 1–3 and 2/263 (0.8%) in Flights 4 and 5. Six patients were asymptomatic on admission, while 3 patients developed symptoms thereafter. None of the participants reported a specific history of contact with animals, going to seafood markets, or visiting medical facilities. Two patients were in contact with an individual who was confirmed or suspected of having COVID-19. Most patients resided in hotels in the center of Wuhan City, taking taxis and trains for commute. Patients relatively adhered to IPC measures such as wearing a mask and hand hygiene. However, emphasis on IPC measures such as universal masking and more rigorous avoidance of exposure risk might have been necessary to prevent infection. In addition, forced social distancing due to lockdown might have contributed to the lower infection rates in Flights 4 and 5, compared to Flights 1–3.
AbstractList We investigated the epidemiological findings regarding the route of coronavirus disease 2019 (COVID-19) and infection prevention and control (IPC) measures among returnees in the emergency evacuation from Wuhan, China to Japan during the COVID-19 outbreak in 2020. A total of 12 of the 14 returnees (median age [range]: 49.5 years [29–65 years]; 9 men [75%]) had confirmed COVID-19. The proportion of returnees with COVID-19 was 12/566 (2.1%) in Flights 1–3 and 2/263 (0.8%) in Flights 4 and 5. Six patients were asymptomatic on admission, while 3 patients developed symptoms thereafter. None of the participants reported a specific history of contact with animals, going to seafood markets, or visiting medical facilities. Two patients were in contact with an individual who was confirmed or suspected of having COVID-19. Most patients resided in hotels in the center of Wuhan City, taking taxis and trains for commute. Patients relatively adhered to IPC measures such as wearing a mask and hand hygiene. However, emphasis on IPC measures such as universal masking and more rigorous avoidance of exposure risk might have been necessary to prevent infection. In addition, forced social distancing due to lockdown might have contributed to the lower infection rates in Flights 4 and 5, compared to Flights 1–3.
We investigated the epidemiological findings regarding the route of coronavirus disease 2019 (COVID-19) and infection prevention and control (IPC) measures among returnees in the emergency evacuation from Wuhan, China to Japan during the COVID-19 outbreak in 2020. A total of 12 of the 14 returnees (median age [range]: 49.5 years [29-65 years]; 9 men [75%]) had confirmed COVID-19. The proportion of returnees with COVID-19 was 12/566 (2.1%) in Flights 1-3 and 2/263 (0.8%) in Flights 4 and 5. Six patients were asymptomatic on admission, while 3 patients developed symptoms thereafter. None of the participants reported a specific history of contact with animals, going to seafood markets, or visiting medical facilities. Two patients were in contact with an individual who was confirmed or suspected of having COVID-19. Most patients resided in hotels in the center of Wuhan City, taking taxis and trains for commute. Patients relatively adhered to IPC measures such as wearing a mask and hand hygiene. However, emphasis on IPC measures such as universal masking and more rigorous avoidance of exposure risk might have been necessary to prevent infection. In addition, forced social distancing due to lockdown might have contributed to the lower infection rates in Flights 4 and 5, compared to Flights 1-3.We investigated the epidemiological findings regarding the route of coronavirus disease 2019 (COVID-19) and infection prevention and control (IPC) measures among returnees in the emergency evacuation from Wuhan, China to Japan during the COVID-19 outbreak in 2020. A total of 12 of the 14 returnees (median age [range]: 49.5 years [29-65 years]; 9 men [75%]) had confirmed COVID-19. The proportion of returnees with COVID-19 was 12/566 (2.1%) in Flights 1-3 and 2/263 (0.8%) in Flights 4 and 5. Six patients were asymptomatic on admission, while 3 patients developed symptoms thereafter. None of the participants reported a specific history of contact with animals, going to seafood markets, or visiting medical facilities. Two patients were in contact with an individual who was confirmed or suspected of having COVID-19. Most patients resided in hotels in the center of Wuhan City, taking taxis and trains for commute. Patients relatively adhered to IPC measures such as wearing a mask and hand hygiene. However, emphasis on IPC measures such as universal masking and more rigorous avoidance of exposure risk might have been necessary to prevent infection. In addition, forced social distancing due to lockdown might have contributed to the lower infection rates in Flights 4 and 5, compared to Flights 1-3.
ArticleNumber JJID.2022.049
Author Tamura, Kaku
Sahara, Toshinori
Ohmagari, Norio
Yamamuro, Ryosuke
Fukushima, Kazuaki
Sekiya, Noritaka
Kutsuna, Satoshi
Nagata, Kaoru
Nomoto, Hidetoshi
Nakamura-Uchiyama, Fukumi
Kawana, Akihiko
Hosokawa, Naoto
Ishikane, Masahiro
Fujikura, Yuji
Osawa, Ryosuke
Imamura, Akifumi
Gu, Yoshiaki
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  fullname: Gu, Yoshiaki
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References_xml – reference: 19. Prem K, Liu Y, Russell TW, et al. The effect of control strategies that reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study. Lancet Public Health. 2020;5:e261-e270.
– reference: 16. Lau H, Khosrawipour V, Kocbach P, et al. The positive impact of lockdown in Wuhan on containing the COVID-19 outbreak in China. J Travel Med. 2020;27:taaa037.
– reference: 1. World Health Organization (WHO). Statement on the second meeting of the International Health Regulations (2005) Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV). January 30, 2020. Available at <https://www.who.int/news/item/30-01-2020-statement-on-the-second-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-of-novel-coronavirus-(2019-ncov)>. Accessed January 11, 2022.
– reference: 20. Wu J, Gamber M, Sun W. Does Wuhan need to be in lockdown during the Chinese Lunar New Year? Int J Environ Res Public Health. 2020;17:1002.
– reference: 17. World Health Organization (WHO). Coronavirus disease 2019 (COVID-19). Situation Report – 28, Februsry 17, 2020. Available at <https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200217-sitrep-28-covid-19.pdf?sfvrsn=a19cf2ad_2>. Accessed May 12, 2022.
– reference: 11. Li Q, Guan X, Wu P, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. New Engl J Med. 2020;382:1199-1207.
– reference: 26. Toyokawa T, Shimada T, Hayamizu T, et al. Transmission of SARS-CoV-2 during a 2-h domestic flight to Okinawa, Japan, March 2020. Influenza Other Respir Viruses. 2022;16:63-71.
– reference: 9. Centers for Disease Control and Prevention (CDC), USA. COVID-19. People with certain medical conditions. Available at <https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/people-with-medical-conditions.html>. Accessed January 11, 2022.
– reference: 5. Kutsuna S, Suzuki T, Hayakawa K, et al. SARS-CoV-2 screening test for Japanese returnees from Wuhan, China, January 2020. Open Forum Infect Dis. 2020;7:ofaa243.
– reference: 15. Hu Y, Kong L, Yao T, et al. Does lock-down of Wuhan effectively restrict early geographic spread of novel coronavirus epidemic during chunyun in China? A spatial model study. BMC Public Health. 2021;21:825.
– reference: 2. Ng OT, Marimuthu K, Chia PY, et al. SARS-CoV-2 infection among travelers returning from Wuhan, China. N Engl J Med. 2020;382:1476-1478.
– reference: 4. Hayakawa K, Kutsuna S, Kawamata T, et al. SARS-CoV-2 infection among returnees on charter flights to Japan from Hubei, China: a report from National Center for Global Health and Medicine. Glob Health Med. 2020;2:107-111.
– reference: 3. Hoehl S, Rabenau H, Berger A, et al. Evidence of SARS-CoV-2 infection in returning travelers from Wuhan, China. N Engl J Med. 2020;382:1278-1280.
– reference: 10. Centers for Disease Control and Prevention (CDC), USA. COVID-19. Clinical Care Considerations; Clinical considerations for care of children and adults with confirmed COVID-19. Available at <https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-guidance-management-patients.html>. Accessed January 11, 2022.
– reference: 24. Nishiura H, Kobayashi T, Miyama T, et al. Estimation of the asymptomatic ratio of novel coronavirus infections (COVID-19). Int J Infect Dis. 2020;94:154-155.
– reference: 23. Sah P, Fitzpatrick MC, Zimmer CF, et al. Asymptomatic SARS-CoV-2 infection: A systematic review and meta-analysis. Proc Natl Acad Sci U S A. 2021;118:e2109229118.
– reference: 6. Kamata K, Jindai K, Ide K, et al. The flight evacuation mission for COVID-19 from Wuhan, China to Tokyo, Japan from January 28 to February 17, 2020. Jpn J Infect Dis. 2021;74:373-376.
– reference: 8. Centers for Disease Control and Prevention (CDC), USA. COVID-19. Scientific Brief: SARS-CoV-2 Transmission. Available at <https://www.cdc.gov/coronavirus/2019-ncov/science/science-briefs/sars-cov-2-transmission.html>. Accessed January 11, 2022.
– reference: 14. World Health Organization (WHO). COVID-19. Avoid the Three Cs. Available at <https://www.who.int/brunei/news/infographics---english>. Accessed January 11, 2022.
– reference: 25. Mizumoto K, Kagaya K, Zarebski A, et al. Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020. Euro Surveill. 2020;25:2000180.
– reference: 12. Maxmen A. WHO report into COVID pandemic origins zeroes in on animal markets, not labs. Nature. 2021;592:173-174.
– reference: 21. World Health Organization (WHO). Advice for the public: Coronavirus disease (COVID-19). Available at <https://www.who.int/emergencies/diseases/novel-coronavirus-2019/advice-for-public>. Accessed January 11, 2022.
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Snippet We investigated the epidemiological findings regarding the route of coronavirus disease 2019 (COVID-19) and infection prevention and control (IPC) measures...
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SubjectTerms China - epidemiology
Communicable Disease Control
Coronaviruses
COVID-19
COVID-19 - epidemiology
Disease control
Epidemiologic Studies
epidemiological features
Epidemiology
evacuation
Hotels
Humans
Hygiene
Infections
Japan - epidemiology
Japanese
SARS-CoV-2
Seafood
Signs and symptoms
Viral diseases
Wuhan China
Title Nationwide Descriptive Epidemiological Study of Patients with COVID-19 Evacuated from Wuhan, China to Japan from January to February, 2020
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https://www.ncbi.nlm.nih.gov/pubmed/36047180
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Volume 76
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