Nationwide Descriptive Epidemiological Study of Patients with COVID-19 Evacuated from Wuhan, China to Japan from January to February, 2020
We investigated the epidemiological findings regarding the route of coronavirus disease 2019 (COVID-19) and infection prevention and control (IPC) measures among returnees in the emergency evacuation from Wuhan, China to Japan during the COVID-19 outbreak in 2020. A total of 12 of the 14 returnees (...
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Published in | Japanese Journal of Infectious Diseases Vol. 76; no. 1; pp. 20 - 26 |
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Main Authors | , , , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
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Japan
National Institute of Infectious Diseases
31.01.2023
Japan Science and Technology Agency |
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Abstract | We investigated the epidemiological findings regarding the route of coronavirus disease 2019 (COVID-19) and infection prevention and control (IPC) measures among returnees in the emergency evacuation from Wuhan, China to Japan during the COVID-19 outbreak in 2020. A total of 12 of the 14 returnees (median age [range]: 49.5 years [29–65 years]; 9 men [75%]) had confirmed COVID-19. The proportion of returnees with COVID-19 was 12/566 (2.1%) in Flights 1–3 and 2/263 (0.8%) in Flights 4 and 5. Six patients were asymptomatic on admission, while 3 patients developed symptoms thereafter. None of the participants reported a specific history of contact with animals, going to seafood markets, or visiting medical facilities. Two patients were in contact with an individual who was confirmed or suspected of having COVID-19. Most patients resided in hotels in the center of Wuhan City, taking taxis and trains for commute. Patients relatively adhered to IPC measures such as wearing a mask and hand hygiene. However, emphasis on IPC measures such as universal masking and more rigorous avoidance of exposure risk might have been necessary to prevent infection. In addition, forced social distancing due to lockdown might have contributed to the lower infection rates in Flights 4 and 5, compared to Flights 1–3. |
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AbstractList | We investigated the epidemiological findings regarding the route of coronavirus disease 2019 (COVID-19) and infection prevention and control (IPC) measures among returnees in the emergency evacuation from Wuhan, China to Japan during the COVID-19 outbreak in 2020. A total of 12 of the 14 returnees (median age [range]: 49.5 years [29–65 years]; 9 men [75%]) had confirmed COVID-19. The proportion of returnees with COVID-19 was 12/566 (2.1%) in Flights 1–3 and 2/263 (0.8%) in Flights 4 and 5. Six patients were asymptomatic on admission, while 3 patients developed symptoms thereafter. None of the participants reported a specific history of contact with animals, going to seafood markets, or visiting medical facilities. Two patients were in contact with an individual who was confirmed or suspected of having COVID-19. Most patients resided in hotels in the center of Wuhan City, taking taxis and trains for commute. Patients relatively adhered to IPC measures such as wearing a mask and hand hygiene. However, emphasis on IPC measures such as universal masking and more rigorous avoidance of exposure risk might have been necessary to prevent infection. In addition, forced social distancing due to lockdown might have contributed to the lower infection rates in Flights 4 and 5, compared to Flights 1–3. We investigated the epidemiological findings regarding the route of coronavirus disease 2019 (COVID-19) and infection prevention and control (IPC) measures among returnees in the emergency evacuation from Wuhan, China to Japan during the COVID-19 outbreak in 2020. A total of 12 of the 14 returnees (median age [range]: 49.5 years [29-65 years]; 9 men [75%]) had confirmed COVID-19. The proportion of returnees with COVID-19 was 12/566 (2.1%) in Flights 1-3 and 2/263 (0.8%) in Flights 4 and 5. Six patients were asymptomatic on admission, while 3 patients developed symptoms thereafter. None of the participants reported a specific history of contact with animals, going to seafood markets, or visiting medical facilities. Two patients were in contact with an individual who was confirmed or suspected of having COVID-19. Most patients resided in hotels in the center of Wuhan City, taking taxis and trains for commute. Patients relatively adhered to IPC measures such as wearing a mask and hand hygiene. However, emphasis on IPC measures such as universal masking and more rigorous avoidance of exposure risk might have been necessary to prevent infection. In addition, forced social distancing due to lockdown might have contributed to the lower infection rates in Flights 4 and 5, compared to Flights 1-3.We investigated the epidemiological findings regarding the route of coronavirus disease 2019 (COVID-19) and infection prevention and control (IPC) measures among returnees in the emergency evacuation from Wuhan, China to Japan during the COVID-19 outbreak in 2020. A total of 12 of the 14 returnees (median age [range]: 49.5 years [29-65 years]; 9 men [75%]) had confirmed COVID-19. The proportion of returnees with COVID-19 was 12/566 (2.1%) in Flights 1-3 and 2/263 (0.8%) in Flights 4 and 5. Six patients were asymptomatic on admission, while 3 patients developed symptoms thereafter. None of the participants reported a specific history of contact with animals, going to seafood markets, or visiting medical facilities. Two patients were in contact with an individual who was confirmed or suspected of having COVID-19. Most patients resided in hotels in the center of Wuhan City, taking taxis and trains for commute. Patients relatively adhered to IPC measures such as wearing a mask and hand hygiene. However, emphasis on IPC measures such as universal masking and more rigorous avoidance of exposure risk might have been necessary to prevent infection. In addition, forced social distancing due to lockdown might have contributed to the lower infection rates in Flights 4 and 5, compared to Flights 1-3. |
ArticleNumber | JJID.2022.049 |
Author | Tamura, Kaku Sahara, Toshinori Ohmagari, Norio Yamamuro, Ryosuke Fukushima, Kazuaki Sekiya, Noritaka Kutsuna, Satoshi Nagata, Kaoru Nomoto, Hidetoshi Nakamura-Uchiyama, Fukumi Kawana, Akihiko Hosokawa, Naoto Ishikane, Masahiro Fujikura, Yuji Osawa, Ryosuke Imamura, Akifumi Gu, Yoshiaki |
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Cites_doi | 10.1038/d41586-021-00865-8 10.1056/NEJMc2003100 10.1016/j.ijid.2020.03.020 10.1186/s12889-021-10837-2 10.3201/eid2607.200994 10.1073/pnas.2109229118 10.7326/M20-0504 10.1111/irv.12913 10.35772/ghm.2020.01036 10.7883/yoken.JJID.2020.938 10.3390/ijerph17031002 10.1056/NEJMc2001899 10.1093/jtm/taaa037 10.2807/1560-7917.ES.2020.25.10.2000180 10.1093/ofid/ofaa243 10.1016/S2468-2667(20)30073-6 10.1056/NEJMoa2001316 |
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Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. New Engl J Med. 2020;382:1199-1207. 23. Sah P, Fitzpatrick MC, Zimmer CF, et al. Asymptomatic SARS-CoV-2 infection: A systematic review and meta-analysis. Proc Natl Acad Sci U S A. 2021;118:e2109229118. 12. Maxmen A. WHO report into COVID pandemic origins zeroes in on animal markets, not labs. Nature. 2021;592:173-174. 17. World Health Organization (WHO). Coronavirus disease 2019 (COVID-19). Situation Report – 28, Februsry 17, 2020. Available at <https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200217-sitrep-28-covid-19.pdf?sfvrsn=a19cf2ad_2>. Accessed May 12, 2022. 22 23 24 25 26 10 11 12 13 14 15 16 17 18 19 1 2 3 4 5 6 7 8 9 20 21 |
References_xml | – reference: 19. Prem K, Liu Y, Russell TW, et al. The effect of control strategies that reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study. Lancet Public Health. 2020;5:e261-e270. – reference: 16. Lau H, Khosrawipour V, Kocbach P, et al. The positive impact of lockdown in Wuhan on containing the COVID-19 outbreak in China. J Travel Med. 2020;27:taaa037. – reference: 1. World Health Organization (WHO). Statement on the second meeting of the International Health Regulations (2005) Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV). January 30, 2020. Available at <https://www.who.int/news/item/30-01-2020-statement-on-the-second-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-of-novel-coronavirus-(2019-ncov)>. Accessed January 11, 2022. – reference: 20. Wu J, Gamber M, Sun W. Does Wuhan need to be in lockdown during the Chinese Lunar New Year? Int J Environ Res Public Health. 2020;17:1002. – reference: 17. World Health Organization (WHO). Coronavirus disease 2019 (COVID-19). Situation Report – 28, Februsry 17, 2020. Available at <https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200217-sitrep-28-covid-19.pdf?sfvrsn=a19cf2ad_2>. Accessed May 12, 2022. – reference: 11. Li Q, Guan X, Wu P, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. New Engl J Med. 2020;382:1199-1207. – reference: 26. Toyokawa T, Shimada T, Hayamizu T, et al. Transmission of SARS-CoV-2 during a 2-h domestic flight to Okinawa, Japan, March 2020. Influenza Other Respir Viruses. 2022;16:63-71. – reference: 9. Centers for Disease Control and Prevention (CDC), USA. COVID-19. People with certain medical conditions. Available at <https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/people-with-medical-conditions.html>. Accessed January 11, 2022. – reference: 5. Kutsuna S, Suzuki T, Hayakawa K, et al. SARS-CoV-2 screening test for Japanese returnees from Wuhan, China, January 2020. Open Forum Infect Dis. 2020;7:ofaa243. – reference: 15. Hu Y, Kong L, Yao T, et al. Does lock-down of Wuhan effectively restrict early geographic spread of novel coronavirus epidemic during chunyun in China? A spatial model study. BMC Public Health. 2021;21:825. – reference: 2. Ng OT, Marimuthu K, Chia PY, et al. SARS-CoV-2 infection among travelers returning from Wuhan, China. N Engl J Med. 2020;382:1476-1478. – reference: 4. Hayakawa K, Kutsuna S, Kawamata T, et al. SARS-CoV-2 infection among returnees on charter flights to Japan from Hubei, China: a report from National Center for Global Health and Medicine. Glob Health Med. 2020;2:107-111. – reference: 3. Hoehl S, Rabenau H, Berger A, et al. Evidence of SARS-CoV-2 infection in returning travelers from Wuhan, China. N Engl J Med. 2020;382:1278-1280. – reference: 10. Centers for Disease Control and Prevention (CDC), USA. COVID-19. Clinical Care Considerations; Clinical considerations for care of children and adults with confirmed COVID-19. Available at <https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-guidance-management-patients.html>. Accessed January 11, 2022. – reference: 24. Nishiura H, Kobayashi T, Miyama T, et al. Estimation of the asymptomatic ratio of novel coronavirus infections (COVID-19). Int J Infect Dis. 2020;94:154-155. – reference: 23. Sah P, Fitzpatrick MC, Zimmer CF, et al. Asymptomatic SARS-CoV-2 infection: A systematic review and meta-analysis. Proc Natl Acad Sci U S A. 2021;118:e2109229118. – reference: 6. Kamata K, Jindai K, Ide K, et al. The flight evacuation mission for COVID-19 from Wuhan, China to Tokyo, Japan from January 28 to February 17, 2020. Jpn J Infect Dis. 2021;74:373-376. – reference: 8. Centers for Disease Control and Prevention (CDC), USA. COVID-19. Scientific Brief: SARS-CoV-2 Transmission. 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Severe acute respiratory syndrome coronavirus 2 infection among returnees to Japan from Wuhan, China, 2020. Emerg Infect Dis. 2020;26:1596-1600. – reference: 13. National Institute of Infectious Diseases, Japan. Manual for the Detection of Pathogen 2019-nCoV Ver.2.6. February 17, 2020. Available at https://www.niid.go.jp/niid/images/epi/corona/2019-nCoVmanual20200217-en.pdf. Accessed January 11, 2022. – reference: 22. Beringer J, George S, Kottasová I. CNN; January 22 coronavirus news. Face masks are made mandatory in Wuhan. January 22, 2020. Available at <https://edition.cnn.com/asia/live-news/wuhan-coronavirus-china-intl-hnk/h_b6ff0d4bd2e53b2ee9e5ca768e231811>. Accessed May 12, 2022. – reference: 18. Lauer SA, Grantz KH, Bi Q, et al. The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: Estimation and application. 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SubjectTerms | China - epidemiology Communicable Disease Control Coronaviruses COVID-19 COVID-19 - epidemiology Disease control Epidemiologic Studies epidemiological features Epidemiology evacuation Hotels Humans Hygiene Infections Japan - epidemiology Japanese SARS-CoV-2 Seafood Signs and symptoms Viral diseases Wuhan China |
Title | Nationwide Descriptive Epidemiological Study of Patients with COVID-19 Evacuated from Wuhan, China to Japan from January to February, 2020 |
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