Redox‐Active Metal Complexes for Anticancer Therapy

• Published in: European journal of inorganic chemistry Vol. 2017; no. 12; pp. 1541 - 1548
• Main Authors: Zhang, Pingyu, Sadler, Peter J.
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley Subscription Services, Inc 27.03.2017
• Subjects: Activation; Anticancer compounds; Anticancer properties; Aquatic plants; Bioinorganic chemistry; Cancer; Coordination compounds; Drugs; Inorganic chemistry; Ligands; Metal complexes; Modulators; Prodrugs; Redox chemistry; Selectivity; Strategy; Therapy; Transition metal compounds

The redox properties of both metals and ligands in transition metal complexes offer unusual routes for new mechanisms of anticancer therapy. Metal complexes can introduce artificial reductive and oxidative stress into cancer cells, including behavior as photoactivatable agents and catalysts. Relativ...