Fundamental aspects of electrospray droplet impact/SIMS

• Published in: Journal of mass spectrometry. Vol. 41; no. 7; pp. 894 - 902
• Main Authors: Hiraoka, Kenzo, Mori, Kunihiko, Asakawa, Daiki
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.07.2006; Wiley
• Subjects: Analytical biochemistry: general aspects, technics, instrumentation; Analytical chemistry; Analytical, structural and metabolic biochemistry; Biological and medical sciences; Chemistry; electrospray droplet impact; Exact sciences and technology; Fundamental and applied biological sciences. Psychology; massive cluster impact; SIMS; Spectrometric and optical methods; electrospray droplet impact; Peptides; massive cluster impact; Secondary ion mass spectrometry; Droplet; Electrospray; Operating conditions; Antibiotic; Gramicidin; Polypeptide; Ionization; SIMS; Antibacterial agent; Mass spectrometry

A new ionization method, electrospray droplet impact ionization (EDI), has been developed for matrix‐free secondary‐ion mass spectrometry (SIMS). The charged droplets formed by electrospraying 1 M acetic acid aqueous solution are sampled through an orifice with a diameter of 400 µm into the first va...