Predictors of hepatitis B e antigen‐negative hepatitis in chronic hepatitis B virus‐infected patients from childhood to adulthood

• Published in: Hepatology (Baltimore, Md.) Vol. 63; no. 1; pp. 74 - 82
• Main Authors: Wu, Jia‐Feng, Chiu, Yu‐Chun, Chang, Kai‐Chi, Chen, Huey‐Ling, Ni, Yen‐Hsuan, Hsu, Hong‐Yuan, Chang, Mei‐Hwei
• Format: Journal Article
• Language: English
• Published: United States Wolters Kluwer Health, Inc 01.01.2016
• Subjects: Adolescent; Age; Age Factors; Antigens; Antiviral agents; Antiviral Agents - therapeutic use; Child; Childhood; Children; Chronic infection; Cohort Studies; Data processing; Female; Follow-Up Studies; Health risk assessment; Hepatitis; Hepatitis B; Hepatitis B e antigen; Hepatitis B e Antigens - blood; Hepatitis B virus; Hepatitis B, Chronic - blood; Hepatitis B, Chronic - drug therapy; Hepatitis B, Chronic - immunology; Hepatology; Humans; Interferon; Interferon-alpha - therapeutic use; Lamivudine; Lamivudine - therapeutic use; Male; Prospective Studies; Risk Factors; Seroconversion; Young Adult; α-Interferon

Hepatitis B e antigen (HBeAg)‐negative hepatitis is a clinical indicator of poor outcome for chronic hepatitis B viral (HBV) infection. This long‐term prospective cohort study aimed to elucidate the predictors of developing HBeAg‐negative hepatitis in chronic HBV‐infected subjects followed from chil...