Diagnosis and testing for growth hormone deficiency across the ages: a global view of the accuracy, caveats, and cut-offs for diagnosis

• Published in: Endocrine Connections Vol. 12; no. 7; pp. 1 - 19
• Main Authors: Yuen, Kevin C J, Johannsson, Gudmundur, Ho, Ken K Y, Miller, Bradley S, Bergada, Ignacio, Rogol, Alan D
• Format: Journal Article
• Language: English
• Published: England Bioscientifica Ltd 01.07.2023; Bioscientifica
• Subjects: adults; children; clonidine; diagnosis; Endocrinology and Diabetes; Endokrinologi och diabetes; glucagon; growth hormone deficiency; insulin; insulin tolerance test; macimorelin; Review; testing; tolerance test; children; adults; testing; clonidine; diagnosis; glucagon; insulin tolerance test; growth hormone deficiency; macimorelin

Growth hormone deficiency (GHD) is a clinical syndrome that can manifest either as isolated or associated with additional pituitary hormone deficiencies. Although diminished height velocity and short stature are useful and important clinical markers to consider testing for GHD in children, the signs...