Design and synthesis of threading intercalators to target DNA - Howell, Lesley A.; Gulam, Rosul; Mueller, Anja; O’Connell, Maria A.; Searcey, Mark (Bioorganic & medicinal chemistry letters, 2010)
Keywords: Acridine; Acridines - chemistry; Acridines - pharmacology; Animals; Antineoplastic agents; Antineoplastic Agents - chemistry; Antitumor activity; Biological and medical sciences; Cell Line, Tumor; DNA; DNA - antagonists & inhibitors; DNA - metabolism; Drug Design; General aspects; Humans; Intercalating Agents - chemical synthesis; Intercalating Agents - pharmacology; Intercalator; Medical sciences; Nucleic Acid Conformation; Pharmacology. Drug treatments; Intercalator; Acridine; DNA; Human; Promyelocytic leukemia; Intercalating agent; Peptides; Acridine derivatives; Cytotoxicity; In vitro; Biological activity; HL60 cell line; Octapeptide; Cell line; Carboxamide; Conjugated compound; Chemical synthesis; Tumor cell