Cellular proliferation and apoptosis in Staphylococcus aureus–infected heifer mammary glands experiencing rapid mammary gland growth

• Published in: Journal of dairy science Vol. 106; no. 4; pp. 2642 - 2650
• Main Authors: Baker, Pari H., Enger, Kellie M., Jacobi, Sheila K., Akers, R. Michael, Enger, Benjamin D.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2023; Elsevier
• Subjects: Animals; Apoptosis; Cattle; Cattle Diseases; Cell Proliferation; dairy science; epithelial cells; epithelium; estradiol; Female; heifers; inflammation; Lactation; mammary glands; Mammary Glands, Animal; mammary growth; mastitis; Mastitis, Bovine - prevention & control; Milk; milk yield; nucleotidyltransferases; progesterone; Staphylococcal Infections - veterinary; Staphylococcus; Staphylococcus aureus - physiology; mastitis; inflammation; mammary growth

Intramammary infections in nonlactating mammary glands are common and can occur during periods of rapid mammary epithelial cell (MEC) accumulation, which may ultimately reduce total MEC numbers. Reduced MEC numbers, resulting from impaired MEC proliferation and increased cellular apoptosis, are expe...