Correlates of spontaneous clearance of hepatitis C virus among people with hemophilia

• Published in: Blood Vol. 107; no. 3; pp. 892 - 897
• Main Authors: Zhang, Mingdong, Rosenberg, Philip S., Brown, Deborah L., Preiss, Liliana, Konkle, Barbara A., Eyster, M. Elaine, Goedert, James J.
• Format: Journal Article
• Language: English
• Published: Washington, DC Elsevier Inc 01.02.2006; The Americain Society of Hematology; 2006 by The American Society of Hematology
• Subjects: Adolescent; Adult; Age Factors; Biological and medical sciences; Blood Component Transfusion; Child; Child, Preschool; Clinical Trials and Observations; Cohort Studies; Female; Hematologic and hematopoietic diseases; Hemophilia A - blood; Hemophilia A - complications; Hemophilia A - therapy; Hemophilia B - blood; Hemophilia B - complications; Hemophilia B - therapy; Hepacivirus; Hepatitis C - blood; Human viral diseases; Humans; Infectious diseases; Male; Medical sciences; Middle Aged; Plasma; Platelet diseases and coagulopathies; Remission, Spontaneous; Retrospective Studies; RNA, Viral - blood; Viral diseases; Viral hepatitis; Virus Inactivation; Human; Mixed infection; Prognosis; Orthohepadnavirus; Hepatic disease; Hemopathy; Clearance; Genetic disease; Infection; Virus; Hepadnaviridae; Viral disease; Cohort study; Hemophilia; Digestive diseases; Hepatitis B virus; Flaviviridae; Hepatitis C virus; Hepacivirus; Coagulopathy; Age; Viral hepatitis C

People with hemophilia were formerly at very high risk of infection with hepatitis C virus (HCV). Approximately 20% of HCV-infected patients spontaneously clear the virus. To identify correlates of spontaneous clearance of HCV, we studied a cohort of HCV-infected hemophilic subjects without human im...