Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes

Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of blood glucose (BG) control on the degree of required medical interventions and on mortality in patients with COVID-19 and T2D remains uncertain. Thus, we performed a retrospective, multi-centered study of 7,337 cases of...

Full description

Saved in:
Bibliographic Details
Published inCell metabolism Vol. 31; no. 6; pp. 1068 - 1077.e3
Main Authors Zhu, Lihua, She, Zhi-Gang, Cheng, Xu, Qin, Juan-Juan, Zhang, Xiao-Jing, Cai, Jingjing, Lei, Fang, Wang, Haitao, Xie, Jing, Wang, Wenxin, Li, Haomiao, Zhang, Peng, Song, Xiaohui, Chen, Xi, Xiang, Mei, Zhang, Chaozheng, Bai, Liangjie, Xiang, Da, Chen, Ming-Ming, Liu, Yanqiong, Yan, Youqin, Liu, Mingyu, Mao, Weiming, Zou, Jinjing, Liu, Liming, Chen, Guohua, Luo, Pengcheng, Xiao, Bing, Zhang, Changjiang, Zhang, Zixiong, Lu, Zhigang, Wang, Junhai, Lu, Haofeng, Xia, Xigang, Wang, Daihong, Liao, Xiaofeng, Peng, Gang, Ye, Ping, Yang, Jun, Yuan, Yufeng, Huang, Xiaodong, Guo, Jiao, Zhang, Bing-Hong, Li, Hongliang
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 02.06.2020
Subjects
Aged
Betacoronavirus - pathogenicity
Blood Glucose - analysis
blood glucose control
Clinical and Translational Report
Coronavirus Infections - complications
Coronavirus Infections - mortality
Coronavirus Infections - pathology
COVID-19
diabetes mellitus
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - complications
Disease Susceptibility - pathology
Female
Glycemic Index - physiology
Hospitalization - statistics & numerical data
Humans
Hyperglycemia - blood
Hyperglycemia - complications
Hypoglycemic Agents - therapeutic use
Longitudinal Studies
Male
Middle Aged
mortality
Multiple Organ Failure - complications
Multiple Organ Failure - mortality
Pandemics
Pneumonia, Viral - complications
Pneumonia, Viral - mortality
Pneumonia, Viral - pathology
Retrospective Studies
SARS-CoV-2
COVID-19
mortality
SARS-CoV-2
diabetes mellitus
blood glucose control
Online AccessGet full text

Cover

Abstract Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of blood glucose (BG) control on the degree of required medical interventions and on mortality in patients with COVID-19 and T2D remains uncertain. Thus, we performed a retrospective, multi-centered study of 7,337 cases of COVID-19 in Hubei Province, China, among which 952 had pre-existing T2D. We found that subjects with T2D required more medical interventions and had a significantly higher mortality (7.8% versus 2.7%; adjusted hazard ratio [HR], 1.49) and multiple organ injury than the non-diabetic individuals. Further, we found that well-controlled BG (glycemic variability within 3.9 to 10.0 mmol/L) was associated with markedly lower mortality compared to individuals with poorly controlled BG (upper limit of glycemic variability exceeding 10.0 mmol/L) (adjusted HR, 0.14) during hospitalization. These findings provide clinical evidence correlating improved glycemic control with better outcomes in patients with COVID-19 and pre-existing T2D. [Display omitted] •A cohort of 7,337 COVID-19 patients with or without diabetes was retrospectively studied•Diabetes status increased the need for medical interventions during COVID-19•Diabetes status increased the mortality risk of patients with COVID-19•Well-controlled blood glucose correlated with improved outcomes in infected patients Type 2 diabetes (T2D) correlates with a worse outcome for COVID-19. Here, Zhu et al. show that among ∼7,300 cases of COVID-19, T2D is associated with a higher death rate, but diabetics with better controlled blood glucose die at a lower rate than diabetics with poorly controlled blood glucose.
AbstractList Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of blood glucose (BG) control on the degree of required medical interventions and on mortality in patients with COVID-19 and T2D remains uncertain. Thus, we performed a retrospective, multi-centered study of 7,337 cases of COVID-19 in Hubei Province, China, among which 952 had pre-existing T2D. We found that subjects with T2D required more medical interventions and had a significantly higher mortality (7.8% versus 2.7%; adjusted hazard ratio [HR], 1.49) and multiple organ injury than the non-diabetic individuals. Further, we found that well-controlled BG (glycemic variability within 3.9 to 10.0 mmol/L) was associated with markedly lower mortality compared to individuals with poorly controlled BG (upper limit of glycemic variability exceeding 10.0 mmol/L) (adjusted HR, 0.14) during hospitalization. These findings provide clinical evidence correlating improved glycemic control with better outcomes in patients with COVID-19 and pre-existing T2D.Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of blood glucose (BG) control on the degree of required medical interventions and on mortality in patients with COVID-19 and T2D remains uncertain. Thus, we performed a retrospective, multi-centered study of 7,337 cases of COVID-19 in Hubei Province, China, among which 952 had pre-existing T2D. We found that subjects with T2D required more medical interventions and had a significantly higher mortality (7.8% versus 2.7%; adjusted hazard ratio [HR], 1.49) and multiple organ injury than the non-diabetic individuals. Further, we found that well-controlled BG (glycemic variability within 3.9 to 10.0 mmol/L) was associated with markedly lower mortality compared to individuals with poorly controlled BG (upper limit of glycemic variability exceeding 10.0 mmol/L) (adjusted HR, 0.14) during hospitalization. These findings provide clinical evidence correlating improved glycemic control with better outcomes in patients with COVID-19 and pre-existing T2D.
Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of blood glucose (BG) control on the degree of required medical interventions and on mortality in patients with COVID-19 and T2D remains uncertain. Thus, we performed a retrospective, multi-centered study of 7,337 cases of COVID-19 in Hubei Province, China, among which 952 had pre-existing T2D. We found that subjects with T2D required more medical interventions and had a significantly higher mortality (7.8% versus 2.7%; adjusted hazard ratio [HR], 1.49) and multiple organ injury than the non-diabetic individuals. Further, we found that well-controlled BG (glycemic variability within 3.9 to 10.0 mmol/L) was associated with markedly lower mortality compared to individuals with poorly controlled BG (upper limit of glycemic variability exceeding 10.0 mmol/L) (adjusted HR, 0.14) during hospitalization. These findings provide clinical evidence correlating improved glycemic control with better outcomes in patients with COVID-19 and pre-existing T2D. [Display omitted] •A cohort of 7,337 COVID-19 patients with or without diabetes was retrospectively studied•Diabetes status increased the need for medical interventions during COVID-19•Diabetes status increased the mortality risk of patients with COVID-19•Well-controlled blood glucose correlated with improved outcomes in infected patients Type 2 diabetes (T2D) correlates with a worse outcome for COVID-19. Here, Zhu et al. show that among ∼7,300 cases of COVID-19, T2D is associated with a higher death rate, but diabetics with better controlled blood glucose die at a lower rate than diabetics with poorly controlled blood glucose.
Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of blood glucose (BG) control on the degree of required medical interventions and on mortality in patients with COVID-19 and T2D remains uncertain. Thus, we performed a retrospective, multi-centered study of 7,337 cases of COVID-19 in Hubei Province, China, among which 952 had pre-existing T2D. We found that subjects with T2D required more medical interventions and had a significantly higher mortality (7.8% versus 2.7%; adjusted hazard ratio [HR], 1.49) and multiple organ injury than the non-diabetic individuals. Further, we found that well-controlled BG (glycemic variability within 3.9 to 10.0 mmol/L) was associated with markedly lower mortality compared to individuals with poorly controlled BG (upper limit of glycemic variability exceeding 10.0 mmol/L) (adjusted HR, 0.14) during hospitalization. These findings provide clinical evidence correlating improved glycemic control with better outcomes in patients with COVID-19 and pre-existing T2D. Type 2 diabetes (T2D) correlates with a worse outcome for COVID-19. Here, Zhu et al. show that among ∼7,300 cases of COVID-19, T2D is associated with a higher death rate, but diabetics with better controlled blood glucose die at a lower rate than diabetics with poorly controlled blood glucose.
Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of blood glucose (BG) control on the degree of required medical interventions and on mortality in patients with COVID-19 and T2D remains uncertain. Thus, we performed a retrospective, multi-centered study of 7,337 cases of COVID-19 in Hubei Province, China, among which 952 had pre-existing T2D. We found that subjects with T2D required more medical interventions and had a significantly higher mortality (7.8% versus 2.7%; adjusted hazard ratio [HR], 1.49) and multiple organ injury than the non-diabetic individuals. Further, we found that well-controlled BG (glycemic variability within 3.9 to 10.0 mmol/L) was associated with markedly lower mortality compared to individuals with poorly controlled BG (upper limit of glycemic variability exceeding 10.0 mmol/L) (adjusted HR, 0.14) during hospitalization. These findings provide clinical evidence correlating improved glycemic control with better outcomes in patients with COVID-19 and pre-existing T2D.
Author Lu, Haofeng
Xia, Xigang
Chen, Xi
Zhang, Peng
Wang, Daihong
Cai, Jingjing
Song, Xiaohui
Chen, Guohua
Li, Haomiao
Lu, Zhigang
Zhang, Zixiong
Guo, Jiao
Liao, Xiaofeng
Li, Hongliang
Yan, Youqin
Liu, Mingyu
Wang, Junhai
She, Zhi-Gang
Chen, Ming-Ming
Huang, Xiaodong
Zou, Jinjing
Peng, Gang
Wang, Wenxin
Yang, Jun
Cheng, Xu
Mao, Weiming
Zhu, Lihua
Xiang, Da
Zhang, Changjiang
Zhang, Bing-Hong
Ye, Ping
Liu, Yanqiong
Liu, Liming
Yuan, Yufeng
Xie, Jing
Zhang, Chaozheng
Lei, Fang
Wang, Haitao
Bai, Liangjie
Xiang, Mei
Luo, Pengcheng
Zhang, Xiao-Jing
Qin, Juan-Juan
Xiao, Bing
Author_xml – sequence: 1
  givenname: Lihua
  surname: Zhu
  fullname: Zhu, Lihua
  organization: Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 410013, China
– sequence: 2
  givenname: Zhi-Gang
  surname: She
  fullname: She, Zhi-Gang
  organization: Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 410013, China
– sequence: 3
  givenname: Xu
  surname: Cheng
  fullname: Cheng, Xu
  organization: Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 410013, China
– sequence: 4
  givenname: Juan-Juan
  surname: Qin
  fullname: Qin, Juan-Juan
  organization: Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 410013, China
– sequence: 5
  givenname: Xiao-Jing
  surname: Zhang
  fullname: Zhang, Xiao-Jing
  organization: Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 410013, China
– sequence: 6
  givenname: Jingjing
  surname: Cai
  fullname: Cai, Jingjing
  organization: Department of Cardiology, The Third Xiangya Hospital, Central South University, Changsha 410000, China
– sequence: 7
  givenname: Fang
  surname: Lei
  fullname: Lei, Fang
  organization: Institute of Model Animal, Wuhan University, Wuhan 430072, China
– sequence: 8
  givenname: Haitao
  surname: Wang
  fullname: Wang, Haitao
  organization: Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430072, China
– sequence: 9
  givenname: Jing
  surname: Xie
  fullname: Xie, Jing
  organization: Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 410013, China
– sequence: 10
  givenname: Wenxin
  surname: Wang
  fullname: Wang, Wenxin
  organization: Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 410013, China
– sequence: 11
  givenname: Haomiao
  surname: Li
  fullname: Li, Haomiao
  organization: Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 410013, China
– sequence: 12
  givenname: Peng
  surname: Zhang
  fullname: Zhang, Peng
  organization: Institute of Model Animal, Wuhan University, Wuhan 430072, China
– sequence: 13
  givenname: Xiaohui
  surname: Song
  fullname: Song, Xiaohui
  organization: Institute of Model Animal, Wuhan University, Wuhan 430072, China
– sequence: 14
  givenname: Xi
  surname: Chen
  fullname: Chen, Xi
  organization: Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430072, China
– sequence: 15
  givenname: Mei
  surname: Xiang
  fullname: Xiang, Mei
  organization: Department of Cardiology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430072, China
– sequence: 16
  givenname: Chaozheng
  surname: Zhang
  fullname: Zhang, Chaozheng
  organization: Institute of Model Animal, Wuhan University, Wuhan 430072, China
– sequence: 17
  givenname: Liangjie
  surname: Bai
  fullname: Bai, Liangjie
  organization: Institute of Model Animal, Wuhan University, Wuhan 430072, China
– sequence: 18
  givenname: Da
  surname: Xiang
  fullname: Xiang, Da
  organization: Institute of Model Animal, Wuhan University, Wuhan 430072, China
– sequence: 19
  givenname: Ming-Ming
  surname: Chen
  fullname: Chen, Ming-Ming
  organization: Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 410013, China
– sequence: 20
  givenname: Yanqiong
  surname: Liu
  fullname: Liu, Yanqiong
  organization: Institute of Model Animal, Wuhan University, Wuhan 430072, China
– sequence: 21
  givenname: Youqin
  surname: Yan
  fullname: Yan, Youqin
  organization: Wuhan Seventh Hospital, Wuhan 430072, China
– sequence: 22
  givenname: Mingyu
  surname: Liu
  fullname: Liu, Mingyu
  organization: The Ninth Hospital of Wuhan City, Wuhan 430072, China
– sequence: 23
  givenname: Weiming
  surname: Mao
  fullname: Mao, Weiming
  organization: Department of General Surgery, Huanggang Central Hospital, Huanggang 438000, China
– sequence: 24
  givenname: Jinjing
  surname: Zou
  fullname: Zou, Jinjing
  organization: Department of Pulmonary and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan 430072, China
– sequence: 25
  givenname: Liming
  surname: Liu
  fullname: Liu, Liming
  organization: Department of General Surgery, Ezhou Central Hospital, Ezhou 436000, China
– sequence: 26
  givenname: Guohua
  surname: Chen
  fullname: Chen, Guohua
  organization: Department of Neurology, Wuhan First Hospital/Wuhan Hospital of Traditional Chinese and Western Medicine, Wuhan 430072, China
– sequence: 27
  givenname: Pengcheng
  surname: Luo
  fullname: Luo, Pengcheng
  organization: Department of Urology, Wuhan Third Hospital and Tongren Hospital of Wuhan University, Wuhan 430072, China
– sequence: 28
  givenname: Bing
  surname: Xiao
  fullname: Xiao, Bing
  organization: Department of Stomatology, Xiantao First People’s Hospital, Xiantao 433000, China
– sequence: 29
  givenname: Changjiang
  surname: Zhang
  fullname: Zhang, Changjiang
  organization: Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 410013, China
– sequence: 30
  givenname: Zixiong
  surname: Zhang
  fullname: Zhang, Zixiong
  organization: The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi 445000, China
– sequence: 31
  givenname: Zhigang
  surname: Lu
  fullname: Lu, Zhigang
  organization: Department of Neurology, The First People’s Hospital of Jingmen affiliated to Hubei Minzu University, Jingmen 448000, China
– sequence: 32
  givenname: Junhai
  surname: Wang
  fullname: Wang, Junhai
  organization: Department of Orthopedics, The First People’s Hospital of Jingmen affiliated to Hubei Minzu University, Jingmen 448000 China
– sequence: 33
  givenname: Haofeng
  surname: Lu
  fullname: Lu, Haofeng
  organization: Department of Hepatobiliary Surgery, The First Affiliated Hospital of Changjiang University, Jingzhou 434000, China
– sequence: 34
  givenname: Xigang
  surname: Xia
  fullname: Xia, Xigang
  organization: Department of Hepatobiliary Surgery, Jingzhou Central Hospital, Jingzhou 434000, China
– sequence: 35
  givenname: Daihong
  surname: Wang
  fullname: Wang, Daihong
  organization: Department of Hepatobiliary and Pancreatic Surgery, Xianning Central Hospital, Xianning 437000, China
– sequence: 36
  givenname: Xiaofeng
  surname: Liao
  fullname: Liao, Xiaofeng
  organization: Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang 441000, China
– sequence: 37
  givenname: Gang
  surname: Peng
  fullname: Peng, Gang
  organization: Department of Hepatobiliary and Pancreatic Surgery, Suizhou Central Hospital Affiliated to Hubei Medical College, Suizhou 441300, China
– sequence: 38
  givenname: Ping
  surname: Ye
  fullname: Ye, Ping
  organization: Department of Cardiology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430072, China
– sequence: 39
  givenname: Jun
  surname: Yang
  fullname: Yang, Jun
  organization: Department of Cardiology, The First College of Clinical Medical Science, China Three Gorges University and Yichang Central People’s Hospital and Institute of Cardiovascular Diseases, China Three Gorges University, Yichang 443000, China
– sequence: 40
  givenname: Yufeng
  surname: Yuan
  fullname: Yuan, Yufeng
  organization: Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430072, China
– sequence: 41
  givenname: Xiaodong
  surname: Huang
  fullname: Huang, Xiaodong
  email: hxd19681031@whu.edu.cn
  organization: Department of Gastroenterology, Wuhan Third Hospital and Tongren Hospital of Wuhan University, Wuhan 430072, China
– sequence: 42
  givenname: Jiao
  surname: Guo
  fullname: Guo, Jiao
  email: guoj@gdpu.edu.cn
  organization: Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine & Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education of China and Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangdong TCM Key Laboratory for Metabolic Diseases, Guangzhou 510006, China
– sequence: 43
  givenname: Bing-Hong
  surname: Zhang
  fullname: Zhang, Bing-Hong
  email: rm001985@whu.edu.cn
  organization: Department of Neonatology, Renmin Hospital of Wuhan University, Wuhan 430072, China
– sequence: 44
  givenname: Hongliang
  surname: Li
  fullname: Li, Hongliang
  email: lihl@whu.edu.cn
  organization: Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 410013, China
BackLink https://www.ncbi.nlm.nih.gov/pubmed/32369736$$D View this record in MEDLINE/PubMed
BookMark eNp9UUtPVDEUbgxGHvoHXJgu3dxrH_fVxJjAgEhCMizQbdP2noFOetux7UX593QYMOqC1Tk5_R7N9x2iPR88IPSekpoS2n1a12aCXDPCSE2amjD6Ch1QwVnVN4zslb1tSdVQTvfRYUprQnjHBX-D9jnjneh5d4DccUrBWJVt8Dis8IkLYcTnbjYhAV4En2NwWPkRL-dswgQJW4-vCh58TviXzbd4sfxxcVpR8Qi7ilDBb5uy9Tf4-n4DmOFTqzRkSG_R65VyCd49zSP0_evZ9eJbdbk8v1gcX1amGXiuBHSGiXaketV0PeNtuQ7AqRZEaG0UN43uaU9HpVouBNOaNbwn5TYMipmWH6EvO93NrCcYTflqVE5uop1UvJdBWfnvi7e38ibcyZ61jHZDEfj4JBDDzxlSlpNNBpxTHsKcJNvatpy3fYF--Nvrj8lzxAUw7AAmhpQirKSx-THvYm2dpERu25RruW1TbtuUpJGlzUJl_1Gf1V8kfd6RoCR8ZyHKZEpZBkYbwWQ5BvsS_QGqb7g2
CitedBy_id crossref_primary_10_1016_j_eprac_2022_05_011
crossref_primary_10_1016_j_medj_2020_06_005
crossref_primary_10_3390_vaccines11101554
crossref_primary_10_2147_DMSO_S351823
crossref_primary_10_1055_s_0040_1715798
crossref_primary_10_1016_j_pcd_2021_08_014
crossref_primary_10_1016_j_cmet_2020_06_015
crossref_primary_10_1016_j_medj_2020_06_008
crossref_primary_10_1371_journal_pone_0243191
crossref_primary_10_1136_bmjopen_2020_039813
crossref_primary_10_4103_jpbs_JPBS_508_20
crossref_primary_10_1371_journal_pone_0248891
crossref_primary_10_3390_jcm11082250
crossref_primary_10_1124_jpet_122_001253
crossref_primary_10_1007_s00592_020_01586_6
crossref_primary_10_3748_wjg_v27_i33_5502
crossref_primary_10_1186_s40001_022_00927_1
crossref_primary_10_1136_bmjebm_2020_111451
crossref_primary_10_1007_s13300_022_01206_2
crossref_primary_10_1016_j_diabres_2020_108550
crossref_primary_10_7759_cureus_40477
crossref_primary_10_1007_s11010_022_04356_w
crossref_primary_10_3389_fpubh_2021_591982
crossref_primary_10_1515_rams_2020_0048
crossref_primary_10_1007_s12020_022_03119_3
crossref_primary_10_1016_j_diabres_2020_108304
crossref_primary_10_1016_j_diabres_2020_108303
crossref_primary_10_1111_1753_0407_13098
crossref_primary_10_4103_jfmpc_jfmpc_278_21
crossref_primary_10_1016_j_diabres_2020_108301
crossref_primary_10_1016_j_diabres_2020_108306
crossref_primary_10_3390_jcm9082368
crossref_primary_10_1186_s13018_020_01976_0
crossref_primary_10_3390_vaccines11020208
crossref_primary_10_13005_bbra_2930
crossref_primary_10_1038_s42255_020_0237_2
crossref_primary_10_2174_18749445_v15_e2201140
crossref_primary_10_1136_bmjopen_2020_045286
crossref_primary_10_1016_j_tifs_2020_12_009
crossref_primary_10_3389_fendo_2021_696087
crossref_primary_10_1016_S2665_9913_21_00316_7
crossref_primary_10_1021_acsomega_1c01375
crossref_primary_10_1186_s12889_023_16218_1
crossref_primary_10_1177_20420188211059882
crossref_primary_10_3389_fmed_2021_758414
crossref_primary_10_2337_dci20_0035
crossref_primary_10_1016_j_arteri_2021_05_001
crossref_primary_10_1186_s12933_023_02097_8
crossref_primary_10_3389_fragi_2021_748591
crossref_primary_10_1136_bmjdrc_2021_002299
crossref_primary_10_4103_ijem_ijem_148_22
crossref_primary_10_3389_fimmu_2021_587146
crossref_primary_10_3390_bios13070678
crossref_primary_10_1021_acsnano_0c08494
crossref_primary_10_1016_j_cegh_2021_100705
crossref_primary_10_3389_fmed_2021_656405
crossref_primary_10_1016_j_mmm_2021_02_013
crossref_primary_10_1080_00325481_2021_1978704
crossref_primary_10_31083_j_rcm_2020_03_78
crossref_primary_10_1016_j_jcjd_2021_11_002
crossref_primary_10_14336_AD_2020_0619
crossref_primary_10_1016_j_mehy_2022_110997
crossref_primary_10_1016_j_endinu_2020_07_002
crossref_primary_10_31793_1680_1466_2021_26_3_227
crossref_primary_10_1111_bcp_14540
crossref_primary_10_3390_tropicalmed7060105
crossref_primary_10_7759_cureus_31793
crossref_primary_10_1111_eci_14049
crossref_primary_10_1016_j_jcte_2021_100265
crossref_primary_10_1210_clinem_dgab918
crossref_primary_10_1016_j_jcte_2021_100262
crossref_primary_10_1186_s12933_024_02333_9
crossref_primary_10_3390_tropicalmed7060104
crossref_primary_10_1159_000512232
crossref_primary_10_18772_26180197_2020_v2n3a1
crossref_primary_10_1016_j_jcte_2021_100268
crossref_primary_10_1210_clinem_dgaa825
crossref_primary_10_3389_fgene_2022_1022739
crossref_primary_10_1007_s13300_021_01133_8
crossref_primary_10_3390_healthcare10030573
crossref_primary_10_1093_bib_bbab206
crossref_primary_10_22207_JPAM_15_2_16
crossref_primary_10_1016_j_ando_2020_05_001
crossref_primary_10_1111_dme_14509
crossref_primary_10_1016_j_pcd_2021_07_013
crossref_primary_10_1055_s_0040_1715108
crossref_primary_10_1007_s13300_022_01228_w
crossref_primary_10_1038_s41392_024_01796_2
crossref_primary_10_2147_CIA_S376519
crossref_primary_10_1136_bmjdrc_2022_002774
crossref_primary_10_4103_jod_jod_120_22
crossref_primary_10_34921_amj_2024_4_005
crossref_primary_10_3390_jcm10081545
crossref_primary_10_4236_ojepi_2021_113020
crossref_primary_10_1002_advs_202104373
crossref_primary_10_2337_dc20_1192
crossref_primary_10_1002_oby_23099
crossref_primary_10_3390_sports9090121
crossref_primary_10_2337_db21_0209
crossref_primary_10_1016_j_numecd_2020_07_007
crossref_primary_10_3390_v13010090
crossref_primary_10_1002_edm2_291
crossref_primary_10_2174_1871530322666220329150238
crossref_primary_10_3390_medicina57121389
crossref_primary_10_2337_dci20_0046
crossref_primary_10_1016_j_therap_2020_05_006
crossref_primary_10_7717_peerj_10800
crossref_primary_10_1016_j_diabres_2020_108346
crossref_primary_10_1016_j_diabres_2020_108587
crossref_primary_10_1016_j_jiph_2021_11_012
crossref_primary_10_1016_j_accpm_2020_10_011
crossref_primary_10_1155_2021_5516192
crossref_primary_10_1371_journal_pcbi_1009183
crossref_primary_10_1055_a_1539_8711
crossref_primary_10_1016_j_pcd_2022_03_015
crossref_primary_10_1530_EJE_21_0068
crossref_primary_10_14341_omet12801
crossref_primary_10_3238_PersDia_2021_05_17_02
crossref_primary_10_14341_DM12873
crossref_primary_10_3389_fmed_2020_590460
crossref_primary_10_4103_jad_jad_142_23
crossref_primary_10_1016_j_artere_2021_06_003
crossref_primary_10_1097_IPC_0000000000000992
crossref_primary_10_1016_j_nutres_2021_04_004
crossref_primary_10_1016_j_cmet_2021_01_016
crossref_primary_10_1111_1753_0407_13085
crossref_primary_10_1007_s13340_021_00507_4
crossref_primary_10_1111_1753_0407_13084
crossref_primary_10_1096_fj_202201340RR
crossref_primary_10_1016_j_stem_2020_06_015
crossref_primary_10_1159_000511354
crossref_primary_10_1016_j_diabres_2020_108374
crossref_primary_10_1177_1932296820965203
crossref_primary_10_1007_s00125_023_05928_1
crossref_primary_10_1016_j_diabres_2023_110896
crossref_primary_10_1038_d41586_020_01891_8
crossref_primary_10_1186_s43556_021_00060_1
crossref_primary_10_1111_cob_12439
crossref_primary_10_3390_jcm10051022
crossref_primary_10_1007_s12020_021_02923_7
crossref_primary_10_1016_j_cmet_2021_01_002
crossref_primary_10_3389_fphar_2020_592439
crossref_primary_10_1016_j_imj_2025_100162
crossref_primary_10_1055_a_1749_2969
crossref_primary_10_1371_journal_ppat_1009634
crossref_primary_10_3389_fendo_2020_574541
crossref_primary_10_1007_s15010_023_02001_2
crossref_primary_10_1080_01676830_2022_2099428
crossref_primary_10_1016_j_clinthera_2023_11_013
crossref_primary_10_1186_s43168_023_00240_3
crossref_primary_10_1016_j_jacc_2021_06_020
crossref_primary_10_2169_internalmedicine_8010_21
crossref_primary_10_3389_fphys_2020_623498
crossref_primary_10_3389_fendo_2020_571037
crossref_primary_10_1016_j_adro_2020_05_009
crossref_primary_10_1093_cid_ciaa1391
crossref_primary_10_1055_a_1686_8738
crossref_primary_10_3390_medicina59101810
crossref_primary_10_1136_bmjdrc_2020_001520
crossref_primary_10_2217_cer_2020_0146
crossref_primary_10_1038_s42255_022_00652_3
crossref_primary_10_1186_s12887_023_03971_w
crossref_primary_10_1007_s00125_020_05216_2
crossref_primary_10_1186_s12985_024_02342_w
crossref_primary_10_3389_fendo_2020_583006
crossref_primary_10_3389_fmed_2021_617659
crossref_primary_10_1371_journal_pone_0290355
crossref_primary_10_1111_dom_14604
crossref_primary_10_1016_j_cmet_2020_08_013
crossref_primary_10_3389_fendo_2021_611526
crossref_primary_10_1111_dom_14608
crossref_primary_10_1111_pedi_13335
crossref_primary_10_1007_s12020_021_02734_w
crossref_primary_10_1093_cid_ciaa1166
crossref_primary_10_1016_j_mayocpiqo_2022_07_004
crossref_primary_10_1016_j_pec_2021_06_030
crossref_primary_10_1016_S2213_8587_21_00244_8
crossref_primary_10_1073_pnas_2117089119
crossref_primary_10_1016_j_lanepe_2021_100105
crossref_primary_10_1038_s42255_022_00567_z
crossref_primary_10_1017_S0950268823001383
crossref_primary_10_1002_iub_2794
crossref_primary_10_1007_s11428_024_01157_1
crossref_primary_10_1016_j_ebiom_2023_104912
crossref_primary_10_1136_bmjdrc_2022_003052
crossref_primary_10_23736_S0022_4707_20_11898_X
crossref_primary_10_3389_fendo_2021_665134
crossref_primary_10_1007_s11010_020_04004_1
crossref_primary_10_1016_j_dsx_2021_05_016
crossref_primary_10_2337_cd22_0083
crossref_primary_10_1016_j_vacun_2022_05_002
crossref_primary_10_20945_2359_3997000000649
crossref_primary_10_1016_j_cellsig_2024_111387
crossref_primary_10_1016_j_mayocpiqo_2021_02_002
crossref_primary_10_4103_ijph_ijph_1908_21
crossref_primary_10_1016_j_cmet_2020_07_007
crossref_primary_10_1097_MD_0000000000023392
crossref_primary_10_1038_s42255_022_00698_3
crossref_primary_10_3346_jkms_2020_35_e328
crossref_primary_10_4103_picr_PICR_168_20
crossref_primary_10_7759_cureus_73313
crossref_primary_10_1016_S2213_8587_20_30342_9
crossref_primary_10_1177_1932296821993198
crossref_primary_10_1016_j_heliyon_2023_e13853
crossref_primary_10_3389_fcimb_2024_1407261
crossref_primary_10_3389_fcvm_2020_593061
crossref_primary_10_1002_edm2_215
crossref_primary_10_1007_s00125_021_05458_8
crossref_primary_10_1016_j_metabol_2022_155330
crossref_primary_10_1002_bies_202000160
crossref_primary_10_7759_cureus_73993
crossref_primary_10_18521_ktd_981790
crossref_primary_10_3389_fendo_2023_1236574
crossref_primary_10_35366_119319
crossref_primary_10_1111_jdi_14118
crossref_primary_10_2139_ssrn_3951144
crossref_primary_10_1016_j_isci_2021_102264
crossref_primary_10_2337_dc21_2102
crossref_primary_10_2196_20259
crossref_primary_10_1177_11795468211010705
crossref_primary_10_3390_ijms222111508
crossref_primary_10_1016_S2213_2600_21_00218_6
crossref_primary_10_1016_j_bios_2022_114254
crossref_primary_10_15829_1728_8800_2021_2750
crossref_primary_10_1016_j_rceng_2021_04_009
crossref_primary_10_4269_ajtmh_20_1110
crossref_primary_10_1155_2022_1607441
crossref_primary_10_2337_db20_0671
crossref_primary_10_1210_clinem_dgab067
crossref_primary_10_3389_fphar_2022_784459
crossref_primary_10_1080_21623945_2024_2423723
crossref_primary_10_1186_s13098_022_00808_x
crossref_primary_10_1186_s43162_023_00266_5
crossref_primary_10_3389_fendo_2021_716625
crossref_primary_10_1177_1535370220973451
crossref_primary_10_1016_j_jdiacomp_2024_108799
crossref_primary_10_33619_2414_2948_67_25
crossref_primary_10_22270_jddt_v14i7_6668
crossref_primary_10_3389_fendo_2022_810914
crossref_primary_10_1177_20420188221110708
crossref_primary_10_3390_biomedicines12020467
crossref_primary_10_1186_s12985_023_01996_2
crossref_primary_10_3389_fmed_2021_744697
crossref_primary_10_3389_fpubh_2021_695139
crossref_primary_10_22159_ajpcr_2024_v17i5_49995
crossref_primary_10_3389_fphys_2020_587013
crossref_primary_10_3389_fendo_2022_780663
crossref_primary_10_54393_pjhs_v3i05_225
crossref_primary_10_1111_obr_13128
crossref_primary_10_2147_DMSO_S498774
crossref_primary_10_1007_s00592_020_01580_y
crossref_primary_10_1016_j_medj_2020_12_013
crossref_primary_10_2196_44209
crossref_primary_10_1016_j_diabres_2020_108514
crossref_primary_10_1002_hsr2_657
crossref_primary_10_25259_IJPP_454_2021
crossref_primary_10_1007_s40618_021_01515_6
crossref_primary_10_1016_j_metop_2022_100163
crossref_primary_10_1186_s12944_021_01564_z
crossref_primary_10_3390_jdb12010009
crossref_primary_10_3389_fendo_2020_574315
crossref_primary_10_1177_2050312120974174
crossref_primary_10_3389_fphys_2021_624698
crossref_primary_10_5812_ijem_120812
crossref_primary_10_1007_s11010_022_04485_2
crossref_primary_10_3390_diabetology3040039
crossref_primary_10_1002_ptr_7461
crossref_primary_10_1111_ahg_12440
crossref_primary_10_1016_j_amjmed_2024_02_029
crossref_primary_10_1016_j_intimp_2021_108456
crossref_primary_10_3390_idr14050073
crossref_primary_10_1016_j_mmm_2020_12_008
crossref_primary_10_1177_00185787211032361
crossref_primary_10_3390_ijms24098034
crossref_primary_10_1016_j_tem_2021_06_004
crossref_primary_10_3389_fpubh_2022_880999
crossref_primary_10_2174_1874467214666210902115650
crossref_primary_10_1016_j_cmet_2024_10_004
crossref_primary_10_1016_j_dsx_2021_102268
crossref_primary_10_1007_s00125_020_05284_4
crossref_primary_10_1177_20499361211027390
crossref_primary_10_1183_16000617_0287_2020
crossref_primary_10_3389_fendo_2022_1002834
crossref_primary_10_1007_s13679_021_00436_y
crossref_primary_10_3390_metabo11100699
crossref_primary_10_1007_s40121_020_00359_6
crossref_primary_10_1016_j_dsx_2020_08_003
crossref_primary_10_1136_bmjdrc_2024_004536
crossref_primary_10_3389_fendo_2023_1129793
crossref_primary_10_1016_j_eclinm_2022_101604
crossref_primary_10_2147_CIA_S285000
crossref_primary_10_3390_jcm9113726
crossref_primary_10_1177_23779608231165485
crossref_primary_10_1530_EC_21_0641
crossref_primary_10_18034_abcjar_v11i1_631
crossref_primary_10_3390_medicina58070848
crossref_primary_10_1093_ije_dyaa180
crossref_primary_10_1002_jmv_26699
crossref_primary_10_3389_fmed_2021_644295
crossref_primary_10_1080_13102818_2022_2090858
crossref_primary_10_1210_clinem_dgac590
crossref_primary_10_1186_s40842_021_00121_y
crossref_primary_10_1177_14791641241288390
crossref_primary_10_1007_s11356_021_14480_7
crossref_primary_10_3389_fpubh_2021_559595
crossref_primary_10_1055_s_0040_1715093
crossref_primary_10_2147_IDR_S307868
crossref_primary_10_3389_fcvm_2020_602183
crossref_primary_10_3390_ijms22147493
crossref_primary_10_1002_jmv_27556
crossref_primary_10_1155_2022_8030765
crossref_primary_10_5492_wjccm_v11_i4_201
crossref_primary_10_3390_jcm12072645
crossref_primary_10_3390_jpm13030392
crossref_primary_10_1172_jci_insight_140327
crossref_primary_10_1038_s41574_023_00833_4
crossref_primary_10_3390_ijerph18084188
crossref_primary_10_1016_S2213_8587_22_00278_9
crossref_primary_10_3389_fendo_2020_585922
crossref_primary_10_1017_S095026882200022X
crossref_primary_10_3389_fcvm_2021_644095
crossref_primary_10_1007_s43440_023_00517_w
crossref_primary_10_1089_dia_2020_0656
crossref_primary_10_2147_JMDH_S313626
crossref_primary_10_1002_jmv_26227
crossref_primary_10_1017_neu_2022_6
crossref_primary_10_1080_16089677_2021_1997427
crossref_primary_10_1007_s40615_022_01351_1
crossref_primary_10_1097_MD_0000000000028561
crossref_primary_10_1080_08830185_2020_1840567
crossref_primary_10_2337_dc22_0708
crossref_primary_10_3390_v16081243
crossref_primary_10_1016_j_biopha_2021_111685
crossref_primary_10_1089_dia_2020_0649
crossref_primary_10_2174_2666145415666221004111511
crossref_primary_10_3389_fendo_2024_1353838
crossref_primary_10_1002_dmrr_3476
crossref_primary_10_1177_20503121241238148
crossref_primary_10_1016_j_diabet_2020_08_004
crossref_primary_10_7759_cureus_32009
crossref_primary_10_1001_jamanetworkopen_2022_44652
crossref_primary_10_1186_s13098_021_00639_2
crossref_primary_10_1007_s40200_020_00646_6
crossref_primary_10_1055_a_2009_6937
crossref_primary_10_3389_fchem_2021_723186
crossref_primary_10_1016_j_lfs_2021_120267
crossref_primary_10_1002_dmrr_3666
crossref_primary_10_1371_journal_pone_0254847
crossref_primary_10_3390_ijms25084440
crossref_primary_10_3390_metabo12060526
crossref_primary_10_1002_osp4_504
crossref_primary_10_3390_pharmaceutics14091828
crossref_primary_10_1007_s00705_021_05012_2
crossref_primary_10_3390_children8020151
crossref_primary_10_3390_medicina57040341
crossref_primary_10_1111_jdi_13425
crossref_primary_10_2337_dc21_2186
crossref_primary_10_1089_vim_2023_0097
crossref_primary_10_3390_jpm12111891
crossref_primary_10_1097_MD_0000000000040873
crossref_primary_10_3390_ijerph17218110
crossref_primary_10_3889_oamjms_2020_5631
crossref_primary_10_7759_cureus_67110
crossref_primary_10_1016_j_diabres_2021_108695
crossref_primary_10_18794_aams_166423
crossref_primary_10_7759_cureus_58889
crossref_primary_10_1016_j_pcd_2022_07_004
crossref_primary_10_4102_phcfm_v13i1_2954
crossref_primary_10_1016_j_tim_2021_03_004
crossref_primary_10_2337_dsi22_0009
crossref_primary_10_3389_fendo_2022_1009028
crossref_primary_10_1038_s42255_021_00347_1
crossref_primary_10_1161_CIR_0000000000001052
crossref_primary_10_4236_aid_2023_134046
crossref_primary_10_3389_fendo_2021_602735
crossref_primary_10_3390_vaccines9020102
crossref_primary_10_1016_j_endien_2021_11_002
crossref_primary_10_1007_s12291_021_00989_8
crossref_primary_10_2337_dc20_1506
crossref_primary_10_1001_jamanetworkopen_2021_40568
crossref_primary_10_1007_s00125_020_05209_1
crossref_primary_10_1016_j_fbio_2021_101172
crossref_primary_10_1016_j_heliyon_2021_e06706
crossref_primary_10_3389_fendo_2020_584642
crossref_primary_10_1016_j_diabres_2021_108682
crossref_primary_10_1016_S2213_8587_20_30238_2
crossref_primary_10_1136_bmjopen_2021_052777
crossref_primary_10_3389_fcimb_2021_778636
crossref_primary_10_2337_dc20_1540
crossref_primary_10_1002_sctm_21_0183
crossref_primary_10_1080_17446651_2022_2002145
crossref_primary_10_1042_BSR20212358
crossref_primary_10_1080_17446651_2022_2002146
crossref_primary_10_1210_clinem_dgac587
crossref_primary_10_1111_fcp_13004
crossref_primary_10_1111_dom_14692
crossref_primary_10_1007_s00125_020_05351_w
crossref_primary_10_1016_j_rce_2021_04_007
crossref_primary_10_3389_fendo_2025_1483962
crossref_primary_10_1055_a_1269_1405
crossref_primary_10_1007_s13300_020_00966_z
crossref_primary_10_1016_j_jsps_2021_06_005
crossref_primary_10_4239_wjd_v12_i3_198
crossref_primary_10_1136_jim_2022_002363
crossref_primary_10_2337_dc20_1521
crossref_primary_10_3390_jof6030163
crossref_primary_10_2174_1871530321666210709164925
crossref_primary_10_1210_clinem_dgab004
crossref_primary_10_1111_apha_13733
crossref_primary_10_1093_cid_ciaa1426
crossref_primary_10_1177_1932296820945297
crossref_primary_10_1016_j_diabres_2022_109813
crossref_primary_10_1507_endocrj_EJ20_0426
crossref_primary_10_7759_cureus_46682
crossref_primary_10_1016_j_diabres_2020_108383
crossref_primary_10_1016_j_dsx_2021_01_015
crossref_primary_10_1016_j_diabres_2020_108386
crossref_primary_10_3389_fphys_2020_584248
crossref_primary_10_1038_s41598_025_91231_5
crossref_primary_10_1016_j_gtc_2023_03_012
crossref_primary_10_1152_physiol_00019_2020
crossref_primary_10_1177_1932296820978399
crossref_primary_10_61186_johe_12_1_18
crossref_primary_10_1177_2050313X21989492
crossref_primary_10_1007_s41999_024_01101_y
crossref_primary_10_12688_hrbopenres_13702_2
crossref_primary_10_1002_oby_23223
crossref_primary_10_1155_2020_5237840
crossref_primary_10_12688_hrbopenres_13702_1
crossref_primary_10_17343_sdutfd_904540
crossref_primary_10_1177_20552076211059350
crossref_primary_10_33590_emjdiabet_21_00133
crossref_primary_10_4093_dmj_2020_0167
crossref_primary_10_2478_rrlm_2023_0002
crossref_primary_10_1111_1753_0407_13137
crossref_primary_10_1111_1753_0407_13135
crossref_primary_10_2147_DMSO_S417925
crossref_primary_10_3389_fendo_2021_741248
crossref_primary_10_1210_clinem_dgab668
crossref_primary_10_1186_s40246_020_00298_w
crossref_primary_10_4239_wjd_v12_i10_1789
crossref_primary_10_1002_jmv_26608
crossref_primary_10_12680_balneo_2020_363
crossref_primary_10_2174_0929867328666210915103431
crossref_primary_10_1136_bmjopen_2021_056027
crossref_primary_10_2217_fmb_2021_0233
crossref_primary_10_14341_DM12501
crossref_primary_10_1016_S2213_8587_20_30271_0
crossref_primary_10_26442_00403660_2022_01_201320
crossref_primary_10_1007_s12020_022_03078_9
crossref_primary_10_3389_fpubh_2025_1435930
crossref_primary_10_1177_1470320320979097
crossref_primary_10_1007_s00592_024_02409_8
crossref_primary_10_15829_1560_4071_2022_4835
crossref_primary_10_35772_ghm_2022_01031
crossref_primary_10_2147_IJGM_S338800
crossref_primary_10_3390_biology11010022
crossref_primary_10_7759_cureus_13902
crossref_primary_10_2337_db22_0264
crossref_primary_10_22209_IC_v62s2a03
crossref_primary_10_1016_S2213_8587_21_00050_4
crossref_primary_10_1016_j_dsx_2020_07_015
crossref_primary_10_1016_j_isci_2022_105319
crossref_primary_10_1016_j_jcjd_2020_10_014
crossref_primary_10_1016_j_metabol_2021_154814
crossref_primary_10_1177_23247096211021231
crossref_primary_10_1016_j_heliyon_2022_e11948
crossref_primary_10_14341_DM12712
crossref_primary_10_14341_DM12954
crossref_primary_10_1515_biol_2021_0034
crossref_primary_10_2147_ORR_S361116
crossref_primary_10_4093_dmj_2020_0146
crossref_primary_10_1016_j_ijregi_2023_10_004
crossref_primary_10_1111_1753_0407_13157
crossref_primary_10_1111_1753_0407_13158
crossref_primary_10_1016_j_biopha_2022_113089
crossref_primary_10_1016_j_jhep_2020_09_027
crossref_primary_10_1371_journal_pone_0252411
crossref_primary_10_3390_healthcare9101315
crossref_primary_10_1093_trstmh_trab035
crossref_primary_10_3390_biomedicines10092089
crossref_primary_10_1111_jdi_13869
crossref_primary_10_1111_imm_13628
crossref_primary_10_4103_epj_epj_36_21
crossref_primary_10_4093_dmj_2020_0138
crossref_primary_10_1002_mnfr_201900480
crossref_primary_10_1097_MD_0000000000032650
crossref_primary_10_1080_13813455_2022_2086265
crossref_primary_10_1016_j_heliyon_2024_e37664
crossref_primary_10_3389_fcell_2021_659809
crossref_primary_10_3389_fphys_2021_747200
crossref_primary_10_1089_dia_2020_0240
crossref_primary_10_2196_42607
crossref_primary_10_3346_jkms_2023_38_e93
crossref_primary_10_1016_j_isci_2020_101611
crossref_primary_10_1007_s13300_020_00873_3
crossref_primary_10_1016_j_dsx_2020_09_009
crossref_primary_10_1038_s41574_020_00462_1
crossref_primary_10_1111_jdi_13813
crossref_primary_10_1038_s41598_022_13816_8
crossref_primary_10_31482_mmsl_2022_004
crossref_primary_10_2337_dc20_1115
crossref_primary_10_3238_PersDia_2020_10_30_01
crossref_primary_10_1159_000529985
crossref_primary_10_3390_nu13092980
crossref_primary_10_3389_fcdhc_2022_826006
crossref_primary_10_1016_j_eclinm_2022_101649
crossref_primary_10_17816_clinutr101434
crossref_primary_10_4158_EP_2020_0466
crossref_primary_10_7717_peerj_14570
crossref_primary_10_1111_jdi_13804
crossref_primary_10_5501_wjv_v12_i3_151
crossref_primary_10_1186_s13098_021_00706_8
crossref_primary_10_1007_s11845_022_03001_1
crossref_primary_10_32947_ajps_v23i1_991
crossref_primary_10_2337_dc20_2676
crossref_primary_10_1016_j_celrep_2022_111708
crossref_primary_10_3389_fcvm_2020_613255
crossref_primary_10_37349_ei_2024_00126
crossref_primary_10_1371_journal_pcbi_1008810
crossref_primary_10_3390_biology10080754
crossref_primary_10_5604_01_3001_0015_8835
crossref_primary_10_1007_s13340_020_00473_3
crossref_primary_10_1016_j_isci_2024_111166
crossref_primary_10_36106_gjra_2712341
crossref_primary_10_1210_jendso_bvaa144
crossref_primary_10_1016_j_micpath_2021_104930
crossref_primary_10_1136_bmjnph_2021_000270
crossref_primary_10_1007_s00125_022_05734_1
crossref_primary_10_3390_clinpract12020021
crossref_primary_10_1080_08923973_2021_1925294
crossref_primary_10_1111_jdi_13845
crossref_primary_10_1016_j_dsx_2020_09_022
crossref_primary_10_3390_biomedicines11030856
crossref_primary_10_3389_fphar_2024_1457672
crossref_primary_10_1111_1753_0407_13121
crossref_primary_10_1186_s12902_021_00717_6
crossref_primary_10_1007_s11239_022_02631_7
crossref_primary_10_23838_pfm_2020_00121
crossref_primary_10_1097_MOL_0000000000000876
crossref_primary_10_1002_jmv_27759
crossref_primary_10_1016_j_eprac_2022_07_014
crossref_primary_10_1093_emph_eoaa036
crossref_primary_10_2337_dbi19_0023
crossref_primary_10_1038_s41467_021_23886_3
crossref_primary_10_1097_MD_0000000000040221
crossref_primary_10_1016_j_it_2022_02_001
crossref_primary_10_1016_j_numecd_2021_08_035
crossref_primary_10_3390_clinpract11010013
crossref_primary_10_1186_s41983_022_00530_5
crossref_primary_10_35772_ghm_2022_01053
crossref_primary_10_1093_cid_ciab801
crossref_primary_10_1002_cplu_202100479
crossref_primary_10_1016_j_metop_2021_100137
crossref_primary_10_5501_wjv_v11_i5_237
crossref_primary_10_1016_j_jdiacomp_2020_107809
crossref_primary_10_1007_s42977_021_00092_2
crossref_primary_10_7759_cureus_39599
crossref_primary_10_1016_j_dsx_2020_05_037
crossref_primary_10_1016_j_dsx_2020_05_039
crossref_primary_10_3390_ijerph17249336
crossref_primary_10_1016_j_sapharm_2024_02_007
crossref_primary_10_3390_jcm11154507
crossref_primary_10_1016_j_isci_2021_102188
crossref_primary_10_1016_j_isci_2021_103030
crossref_primary_10_1016_j_diabres_2021_108936
crossref_primary_10_1080_17446651_2020_1774360
crossref_primary_10_1177_1932296820964264
crossref_primary_10_35366_111119
crossref_primary_10_1371_journal_pone_0294436
crossref_primary_10_1111_dme_14815
crossref_primary_10_1186_s12982_024_00225_7
crossref_primary_10_1016_j_jpba_2022_115224
crossref_primary_10_1016_j_csbr_2024_100015
crossref_primary_10_1016_j_pcd_2020_06_010
crossref_primary_10_12998_wjcc_v8_i22_5576
crossref_primary_10_1016_j_redare_2021_02_008
crossref_primary_10_1042_CS20200752
crossref_primary_10_1007_s13340_024_00746_1
crossref_primary_10_1155_2021_9101082
crossref_primary_10_3389_fitd_2022_801276
crossref_primary_10_1007_s12020_020_02444_9
crossref_primary_10_2337_dc21_1709
crossref_primary_10_2217_fvl_2022_0112
crossref_primary_10_1055_a_1300_2550
crossref_primary_10_1038_s41598_020_77632_8
crossref_primary_10_1371_journal_pone_0286815
crossref_primary_10_20961_plexus_v2i3_558
crossref_primary_10_3389_fendo_2020_00525
crossref_primary_10_14814_phy2_15369
crossref_primary_10_3389_fendo_2020_00526
crossref_primary_10_1093_jn_nxab059
crossref_primary_10_1155_2021_8812304
crossref_primary_10_1177_20499361211009380
crossref_primary_10_1186_s12933_020_01089_2
crossref_primary_10_4103_abr_abr_177_21
crossref_primary_10_1097_JOM_0000000000002118
crossref_primary_10_1038_s41588_023_01462_3
crossref_primary_10_1007_s11626_022_00691_w
crossref_primary_10_1016_j_diabres_2020_108437
crossref_primary_10_1186_s12933_021_01336_0
crossref_primary_10_2147_DMSO_S450230
crossref_primary_10_2337_dbi21_0029
crossref_primary_10_3389_fendo_2022_847993
crossref_primary_10_15252_emmm_202013038
crossref_primary_10_1007_s40618_021_01669_3
crossref_primary_10_2337_dc21_0604
crossref_primary_10_3389_fphar_2022_791074
crossref_primary_10_1002_jgh3_12465
crossref_primary_10_1080_09537104_2021_1962519
crossref_primary_10_56226_ihr_v1i2_29
crossref_primary_10_1016_j_obmed_2020_100316
crossref_primary_10_3390_pathogens12020184
crossref_primary_10_3390_v15071468
crossref_primary_10_3389_fpubh_2022_908756
crossref_primary_10_4239_wjd_v15_i8_1663
crossref_primary_10_1080_03007995_2021_1904862
crossref_primary_10_1016_j_diabres_2020_108448
crossref_primary_10_1016_j_sciaf_2022_e01183
crossref_primary_10_3390_cancers13194749
crossref_primary_10_1016_j_jbmt_2024_05_035
crossref_primary_10_1016_j_dsx_2020_12_029
crossref_primary_10_1080_17446651_2025_2469627
crossref_primary_10_1016_j_diabet_2020_05_001
crossref_primary_10_1002_ajh_26964
crossref_primary_10_2337_dc20_1088
crossref_primary_10_36150_2499_6564_265
crossref_primary_10_1016_j_pcd_2023_05_009
crossref_primary_10_3390_ijms241612782
crossref_primary_10_1111_1753_0407_13181
crossref_primary_10_1007_s11033_023_08493_3
crossref_primary_10_1111_joor_13684
crossref_primary_10_3389_fmed_2021_655604
crossref_primary_10_1002_rmv_2505
crossref_primary_10_1007_s13300_021_01110_1
crossref_primary_10_3803_EnM_2020_301
crossref_primary_10_1016_j_diabet_2020_05_008
crossref_primary_10_1016_j_diabres_2020_108217
crossref_primary_10_1111_jch_14146
crossref_primary_10_1016_j_dsx_2020_12_013
crossref_primary_10_4103_jdmimsu_jdmimsu_395_21
crossref_primary_10_1016_j_dsx_2020_12_014
crossref_primary_10_1080_14787210_2021_1964955
crossref_primary_10_1136_bmjopen_2020_044028
crossref_primary_10_3389_fimmu_2020_01762
crossref_primary_10_33590_emj_EMCE4327
crossref_primary_10_1016_j_arteri_2020_10_001
crossref_primary_10_14260_jemds_2021_658
crossref_primary_10_3390_metabo12111116
crossref_primary_10_3389_fmolb_2020_588618
crossref_primary_10_14341_DM12786
crossref_primary_10_1111_ijcp_14833
crossref_primary_10_3389_fendo_2022_974540
crossref_primary_10_1002_clc_23465
crossref_primary_10_1016_S2213_8587_20_30110_8
crossref_primary_10_1016_j_diabres_2020_108227
crossref_primary_10_1093_jmcb_mjaa054
crossref_primary_10_2147_IDR_S367012
crossref_primary_10_3389_fimmu_2023_1079277
crossref_primary_10_1097_QAI_0000000000002799
crossref_primary_10_1111_1753_0407_13171
crossref_primary_10_1111_cen_14288
crossref_primary_10_2337_dc20_2192
crossref_primary_10_70315_uloap_ulmhs_2024_0204001
crossref_primary_10_3389_fcdhc_2022_812134
crossref_primary_10_1109_TNB_2023_3303345
crossref_primary_10_4103_jpgm_JPGM_602_20
crossref_primary_10_3390_antiox11010140
crossref_primary_10_1007_s13300_021_01158_z
crossref_primary_10_1007_s42399_020_00363_4
crossref_primary_10_4103_mjbl_mjbl_253_23
crossref_primary_10_1016_j_cegh_2022_101110
crossref_primary_10_1016_j_heliyon_2024_e37615
crossref_primary_10_4014_jmb_2206_06064
crossref_primary_10_3390_cells11060932
crossref_primary_10_7554_eLife_79946
crossref_primary_10_21931_RB_2023_08_02_47
crossref_primary_10_2169_internalmedicine_8041_21
crossref_primary_10_1007_s40619_021_00949_7
crossref_primary_10_3390_ijms22052681
crossref_primary_10_1016_j_diabet_2020_11_005
crossref_primary_10_1016_j_dld_2020_09_007
crossref_primary_10_3389_fmed_2021_585851
crossref_primary_10_1007_s13340_024_00715_8
crossref_primary_10_1249_JES_0000000000000284
crossref_primary_10_1177_0036933020953516
crossref_primary_10_1038_s41467_022_33218_8
crossref_primary_10_1073_pnas_2101071118
crossref_primary_10_3390_brainsci10121012
crossref_primary_10_1016_j_crphar_2021_100063
crossref_primary_10_1186_s13256_020_02624_1
crossref_primary_10_1186_s13578_022_00766_x
crossref_primary_10_1007_s13762_022_04326_1
crossref_primary_10_1186_s43168_021_00099_2
crossref_primary_10_1016_j_diabres_2020_108246
crossref_primary_10_1186_s13098_023_01228_1
crossref_primary_10_23736_S0391_1977_20_03216_2
crossref_primary_10_4102_phcfm_v13i1_2648
crossref_primary_10_26442_20751753_2023_4_202216
crossref_primary_10_1016_j_jdiacomp_2021_107927
crossref_primary_10_3390_endocrines2030031
crossref_primary_10_1016_j_joms_2021_12_015
crossref_primary_10_1002_hsr2_1416
crossref_primary_10_1016_j_lfs_2021_119510
crossref_primary_10_1002_pdi_2271
crossref_primary_10_1177_15598276241269532
crossref_primary_10_1016_j_cytogfr_2020_05_009
crossref_primary_10_1016_j_dsx_2020_11_014
crossref_primary_10_1021_acs_jmedchem_1c01737
crossref_primary_10_2337_dc20_1714
crossref_primary_10_1002_oby_22938
crossref_primary_10_6065_apem_2142082_041
crossref_primary_10_4103_ijmr_ijmr_2605_21
crossref_primary_10_1016_j_pcd_2022_08_005
crossref_primary_10_1016_j_rmed_2024_107540
crossref_primary_10_1007_s10787_022_01061_4
crossref_primary_10_1016_j_cmet_2021_06_004
crossref_primary_10_4068_cmj_2021_57_2_103
crossref_primary_10_1002_jmv_28234
crossref_primary_10_2196_19581
crossref_primary_10_1097_MED_0000000000000598
crossref_primary_10_3389_fvets_2023_1086003
crossref_primary_10_1016_j_ijid_2022_05_060
crossref_primary_10_3390_ph15070794
crossref_primary_10_1016_j_pcd_2023_02_006
crossref_primary_10_1111_jdi_14021
crossref_primary_10_3390_biology11030400
crossref_primary_10_1016_j_jdiacomp_2020_107666
crossref_primary_10_5551_jat_64062
crossref_primary_10_1080_17446651_2021_1927708
crossref_primary_10_32902_2663_0338_2023_4_45_50
crossref_primary_10_1007_s11010_022_04593_z
crossref_primary_10_1002_pdi_2291
crossref_primary_10_1007_s11892_020_01366_0
crossref_primary_10_1007_s11892_022_01452_5
crossref_primary_10_3389_fmolb_2021_632290
crossref_primary_10_20945_2359_3997000000527
crossref_primary_10_1080_07853890_2020_1836566
crossref_primary_10_2174_2210315512666220520151227
crossref_primary_10_1016_j_jdiacomp_2020_107671
crossref_primary_10_1016_j_diabres_2021_108753
crossref_primary_10_3389_fcimb_2021_638852
crossref_primary_10_18231_j_ijcbr_2021_035
crossref_primary_10_2174_1381612829666221123111849
crossref_primary_10_18699_SSMJ20220101
crossref_primary_10_1016_S2213_8587_20_30221_7
crossref_primary_10_1016_j_jvs_2021_01_051
crossref_primary_10_1136_bmjopen_2021_051237
crossref_primary_10_2174_0929867329666220729154615
crossref_primary_10_1136_bmjdrc_2020_001858
crossref_primary_10_3390_jcm13247510
crossref_primary_10_4178_epih_e2021035
crossref_primary_10_1155_2023_8700302
crossref_primary_10_5937_arhfarm72_36369
crossref_primary_10_1007_s00592_020_01592_8
crossref_primary_10_1136_bmjdrc_2020_001851
crossref_primary_10_37689_acta_ape_2022AO03722
crossref_primary_10_1186_s40249_024_01263_8
crossref_primary_10_1016_j_cmet_2021_09_009
crossref_primary_10_1371_journal_pgph_0001100
crossref_primary_10_1038_s41575_022_00698_4
crossref_primary_10_1016_j_orcp_2021_05_001
crossref_primary_10_17925_EE_2020_16_2_85
crossref_primary_10_3389_fendo_2023_1248676
crossref_primary_10_1002_edm2_338
crossref_primary_10_3390_su131810212
crossref_primary_10_3390_jrfm13090194
crossref_primary_10_3389_fendo_2021_620566
crossref_primary_10_1007_s13300_020_00858_2
crossref_primary_10_3389_fgwh_2022_756362
crossref_primary_10_3389_fpsyg_2023_1209021
crossref_primary_10_5492_wjccm_v11_i4_219
crossref_primary_10_1016_j_diabres_2020_108619
crossref_primary_10_1016_j_biopha_2022_113801
crossref_primary_10_1016_j_clim_2020_108651
crossref_primary_10_1210_endrev_bnad032
crossref_primary_10_3389_fendo_2020_596898
crossref_primary_10_3390_v13050835
crossref_primary_10_3389_fgene_2021_782172
crossref_primary_10_1016_j_dsx_2020_10_011
crossref_primary_10_1007_s13300_020_00847_5
crossref_primary_10_1177_1035719X211040857
crossref_primary_10_1016_j_diabres_2021_108977
crossref_primary_10_1093_qjmed_hcac020
crossref_primary_10_15212_bioi_2020_0035
crossref_primary_10_1371_journal_pone_0265473
crossref_primary_10_3390_biomedicines12091997
crossref_primary_10_7554_eLife_78200
crossref_primary_10_1016_j_metabol_2022_155223
crossref_primary_10_3389_fendo_2021_596518
crossref_primary_10_1016_j_diabet_2021_101307
crossref_primary_10_1002_jpen_2032
crossref_primary_10_3389_fendo_2022_919223
crossref_primary_10_1186_s12933_022_01625_2
crossref_primary_10_1017_S0007114520003529
crossref_primary_10_17816_PED1255_25
crossref_primary_10_1007_s12020_024_04006_9
crossref_primary_10_1007_s11684_020_0825_2
crossref_primary_10_4236_oji_2022_122003
crossref_primary_10_1016_j_dsx_2021_102248
crossref_primary_10_1016_j_eprac_2021_01_011
crossref_primary_10_53394_akd_956513
crossref_primary_10_1042_BSR20230293
crossref_primary_10_1016_j_dsx_2021_102244
crossref_primary_10_1073_pnas_2220329120
crossref_primary_10_1186_s12911_021_01712_6
crossref_primary_10_3390_vaccines10040527
crossref_primary_10_1038_s41574_020_00435_4
crossref_primary_10_1016_j_diabres_2021_108955
crossref_primary_10_3389_fendo_2021_587801
crossref_primary_10_18632_aging_202456
crossref_primary_10_1016_j_diabet_2020_101216
crossref_primary_10_3389_fendo_2021_772865
crossref_primary_10_3389_fimmu_2021_677008
crossref_primary_10_3390_jcm12072555
crossref_primary_10_1016_j_dsx_2022_102439
crossref_primary_10_7759_cureus_35165
crossref_primary_10_22141_2224_1485_14_5_2021_245241
crossref_primary_10_1055_a_2421_0071
crossref_primary_10_1016_j_arcmed_2021_08_002
crossref_primary_10_3164_jcbn_21_31
crossref_primary_10_1177_15353702221108914
crossref_primary_10_3389_fendo_2022_861443
crossref_primary_10_3389_fendo_2023_1109673
crossref_primary_10_1016_j_diabet_2020_101222
crossref_primary_10_3389_fendo_2020_600439
crossref_primary_10_1016_j_diabet_2020_07_006
crossref_primary_10_1016_j_molmet_2020_101044
crossref_primary_10_1038_s41586_022_05128_8
crossref_primary_10_3390_jcm10184098
crossref_primary_10_3390_nu14061305
crossref_primary_10_3390_jcm11154574
crossref_primary_10_1016_j_jacc_2020_07_069
crossref_primary_10_3389_fendo_2022_1007171
crossref_primary_10_1038_s41598_021_88014_z
crossref_primary_10_2144_btn_2020_0096
crossref_primary_10_1152_ajpcell_00426_2020
crossref_primary_10_1038_s41598_022_26657_2
crossref_primary_10_3390_jpm10040145
crossref_primary_10_7762_cnr_2022_11_4_331
crossref_primary_10_1007_s00592_020_01636_z
crossref_primary_10_4103_jcsr_jcsr_88_22
crossref_primary_10_3390_v16010161
crossref_primary_10_5114_bta_2023_127206
crossref_primary_10_1002_advs_202101222
crossref_primary_10_1038_s41366_021_00872_9
crossref_primary_10_1136_bmjopen_2024_084087
crossref_primary_10_3889_oamjms_2021_6597
crossref_primary_10_4103_jfmpc_jfmpc_192_22
crossref_primary_10_1016_j_hnm_2024_200255
crossref_primary_10_1155_2021_9526701
crossref_primary_10_14341_probl12840
crossref_primary_10_1111_bjh_18121
crossref_primary_10_1097_JSM_0000000000000915
crossref_primary_10_4239_wjd_v12_i9_1401
crossref_primary_10_1016_j_jcjd_2023_02_005
crossref_primary_10_1016_j_eprac_2021_07_016
crossref_primary_10_1210_jendso_bvab141
crossref_primary_10_3390_ijms22158255
crossref_primary_10_1016_j_ijid_2020_09_008
crossref_primary_10_3389_fmed_2023_1079165
crossref_primary_10_55544_jrasb_3_3_16
crossref_primary_10_1016_j_lfs_2021_119371
crossref_primary_10_1038_s41366_021_01017_8
crossref_primary_10_1186_s12879_024_09084_8
crossref_primary_10_1038_s41598_022_18786_5
crossref_primary_10_1007_s13300_021_01170_3
crossref_primary_10_1016_j_virol_2021_10_003
crossref_primary_10_1055_a_2045_7787
crossref_primary_10_3389_fnut_2022_906243
crossref_primary_10_1016_j_jinf_2020_07_006
crossref_primary_10_1111_imj_15975
crossref_primary_10_7759_cureus_10350
crossref_primary_10_1002_dmrr_3360
crossref_primary_10_1016_j_isci_2022_105038
crossref_primary_10_1080_17446651_2021_1909472
crossref_primary_10_2174_0929867329666220430131018
crossref_primary_10_3389_fendo_2021_731974
crossref_primary_10_1007_s40121_020_00338_x
crossref_primary_10_2337_dc21_0065
crossref_primary_10_20996_1819_6446_2024_3148
crossref_primary_10_1016_j_intimp_2020_106980
crossref_primary_10_1371_journal_pone_0243602
crossref_primary_10_3389_fendo_2021_727419
crossref_primary_10_1016_j_virusres_2022_199010
crossref_primary_10_21518_2079_701X_2022_16_10_40_45
crossref_primary_10_4103_jfmpc_jfmpc_845_20
crossref_primary_10_3390_ijerph19116555
crossref_primary_10_1093_cvr_cvad031
crossref_primary_10_1111_jcmm_16431
crossref_primary_10_2337_dc20_1444
crossref_primary_10_3390_healthcare9070788
crossref_primary_10_1142_S0192415X21500373
crossref_primary_10_2337_dc20_1448
crossref_primary_10_2478_jtim_2021_0016
crossref_primary_10_4103_jfmpc_jfmpc_364_22
crossref_primary_10_1007_s00431_023_04958_6
crossref_primary_10_1136_bmjopen_2020_044526
crossref_primary_10_7143_jhep_2024_28
crossref_primary_10_2337_dbi20_0045
crossref_primary_10_1177_15598276211050339
crossref_primary_10_12974_2311_858X_2023_11_4
crossref_primary_10_1016_j_cmet_2021_05_015
crossref_primary_10_1016_j_bbcan_2021_188527
crossref_primary_10_1515_jom_2021_0182
crossref_primary_10_3390_nu14173493
crossref_primary_10_1016_j_endmts_2024_100196
crossref_primary_10_1097_JBR_0000000000000150
crossref_primary_10_1007_s13410_023_01261_w
crossref_primary_10_1159_000520419
crossref_primary_10_1111_jdi_13546
crossref_primary_10_1016_j_autneu_2021_102810
crossref_primary_10_1080_07435800_2021_1967376
crossref_primary_10_1186_s12967_022_03407_6
crossref_primary_10_21673_anadoluklin_909018
crossref_primary_10_1053_j_gastro_2021_09_009
crossref_primary_10_18705_1607_419X_2021_27_6_642_652
crossref_primary_10_1210_jendso_bvaa082
crossref_primary_10_2147_IJGM_S332755
crossref_primary_10_1007_s11357_025_01591_z
crossref_primary_10_2337_dbi20_0032
crossref_primary_10_1080_14656566_2020_1837114
crossref_primary_10_1016_j_cmet_2020_11_014
crossref_primary_10_1016_j_cmet_2020_11_015
crossref_primary_10_2147_DMSO_S332819
crossref_primary_10_1007_s13340_023_00656_8
crossref_primary_10_3390_ijms241411576
crossref_primary_10_3389_fmicb_2022_1042362
crossref_primary_10_2337_dc20_0780
crossref_primary_10_3390_covid4040029
crossref_primary_10_3389_fimmu_2022_890517
crossref_primary_10_1111_jdi_13537
crossref_primary_10_1093_ofid_ofab284
crossref_primary_10_1186_s12979_020_00192_y
crossref_primary_10_1186_s12933_022_01569_7
crossref_primary_10_1097_CRD_0000000000000405
crossref_primary_10_1016_j_vacune_2022_10_014
crossref_primary_10_2337_dbi20_0022
crossref_primary_10_1080_07391102_2022_2059568
crossref_primary_10_1097_CRD_0000000000000408
crossref_primary_10_1089_tmj_2020_0554
crossref_primary_10_1002_dmrr_3565
crossref_primary_10_3389_fcell_2022_824851
crossref_primary_10_1016_j_nmni_2020_100797
crossref_primary_10_1007_s11154_021_09630_8
crossref_primary_10_4093_jkd_2020_21_3_120
crossref_primary_10_1016_j_heliyon_2020_e05411
crossref_primary_10_1016_j_eprac_2021_07_008
crossref_primary_10_1111_cts_12897
crossref_primary_10_1111_jdi_13326
crossref_primary_10_1016_j_meegid_2022_105254
crossref_primary_10_1007_s10787_023_01239_4
crossref_primary_10_3390_diseases12070143
crossref_primary_10_4103_tcmj_tcmj_144_22
crossref_primary_10_4331_wjbc_v14_i2_40
crossref_primary_10_1016_S0140_6736_20_32374_6
crossref_primary_10_1016_j_humgen_2022_201039
crossref_primary_10_1007_s00018_024_05568_7
crossref_primary_10_3390_cimb44020055
crossref_primary_10_7759_cureus_47654
crossref_primary_10_1111_febs_15613
crossref_primary_10_2337_dc20_2733
crossref_primary_10_1016_j_eprac_2020_12_015
crossref_primary_10_1016_j_fshw_2021_07_013
crossref_primary_10_1016_j_intimp_2022_109325
crossref_primary_10_15406_emij_2020_08_00286
crossref_primary_10_1038_s41392_023_01510_8
crossref_primary_10_1136_bmjopen_2023_078135
crossref_primary_10_1016_j_diabres_2021_108789
crossref_primary_10_1002_hsr2_70488
crossref_primary_10_1515_jpem_2021_0099
crossref_primary_10_1210_endocr_bqaa154
crossref_primary_10_1016_j_biopsych_2020_12_014
crossref_primary_10_3390_ijms222011028
crossref_primary_10_1016_j_diabres_2020_108266
crossref_primary_10_4239_wjd_v12_i10_1674
crossref_primary_10_1016_j_redar_2021_02_002
crossref_primary_10_1002_jmv_26712
crossref_primary_10_1016_j_cmet_2021_02_006
crossref_primary_10_1016_j_eprac_2021_05_011
crossref_primary_10_3390_ijerph19095354
crossref_primary_10_1186_s12916_021_02058_6
crossref_primary_10_1210_clinem_dgab792
crossref_primary_10_1177_2042018821996482
crossref_primary_10_3390_ph14111196
crossref_primary_10_1016_j_jdiacomp_2021_108100
crossref_primary_10_1186_s40842_022_00141_2
crossref_primary_10_3389_fendo_2021_640529
crossref_primary_10_1016_S2666_7568_20_30047_7
crossref_primary_10_1111_dom_14393
crossref_primary_10_4103_jfmpc_jfmpc_709_22
crossref_primary_10_3389_fnut_2023_1122203
crossref_primary_10_1007_s00592_020_01654_x
crossref_primary_10_1016_j_eclinm_2021_101025
crossref_primary_10_1016_j_molcel_2022_10_026
crossref_primary_10_3389_frans_2022_846102
crossref_primary_10_1590_s1678_9946202264074
crossref_primary_10_1016_j_pcd_2022_12_002
crossref_primary_10_1007_s11154_022_09714_z
crossref_primary_10_3390_diseases13030067
crossref_primary_10_1007_s40200_021_00922_z
crossref_primary_10_1016_j_diabres_2020_108268
crossref_primary_10_3390_nu14142925
crossref_primary_10_1016_j_bbadis_2021_166260
crossref_primary_10_4329_wjr_v14_i1_13
crossref_primary_10_1016_j_diabres_2020_108286
crossref_primary_10_4102_safp_v65i1_5631
crossref_primary_10_3390_jcm9072288
crossref_primary_10_1111_bcp_15258
crossref_primary_10_1016_j_pupt_2021_102035
crossref_primary_10_1111_dom_14134
crossref_primary_10_1111_jdi_13526
crossref_primary_10_1016_j_metabol_2020_154417
crossref_primary_10_1111_dom_14132
crossref_primary_10_1097_CD9_0000000000000038
crossref_primary_10_29001_2073_8552_2022_37_4_22_30
crossref_primary_10_1186_s12879_021_06369_0
crossref_primary_10_2147_DMSO_S268481
crossref_primary_10_1007_s11033_024_09291_1
crossref_primary_10_1016_j_diabres_2020_108296
crossref_primary_10_23736_S0393_3660_22_04901_4
crossref_primary_10_3389_fcvm_2020_629933
crossref_primary_10_14218_ERHM_2020_00046
crossref_primary_10_12998_wjcc_v9_i28_8327
crossref_primary_10_1042_BSR20203584
crossref_primary_10_1016_j_diabres_2020_108299
crossref_primary_10_1016_j_ijans_2022_100419
crossref_primary_10_1038_s41392_021_00726_w
crossref_primary_10_1136_bmjdrc_2021_002692
crossref_primary_10_1007_s11154_021_09663_z
crossref_primary_10_1016_j_diabres_2021_109041
crossref_primary_10_1016_j_uclim_2021_100944
crossref_primary_10_1007_s12020_021_02729_7
crossref_primary_10_1186_s43556_024_00183_1
crossref_primary_10_1016_j_diabres_2020_108291
crossref_primary_10_2337_dc20_1295
crossref_primary_10_4103_jod_jod_106_20
crossref_primary_10_3389_fendo_2021_732431
crossref_primary_10_1111_jdi_13754
crossref_primary_10_1016_j_metabol_2020_154401
crossref_primary_10_1136_bmjdrc_2021_002203
crossref_primary_10_1371_journal_pmed_1003553
crossref_primary_10_3390_v13061177
crossref_primary_10_2147_IDR_S362140
crossref_primary_10_1210_endocr_bqaa112
crossref_primary_10_5888_pcd18_210123
crossref_primary_10_5144_0256_4947_2024_116
crossref_primary_10_1016_j_arcmed_2021_04_001
crossref_primary_10_1186_s13063_023_07243_x
crossref_primary_10_3390_pathogens10091109
crossref_primary_10_1134_S2079057020040062
crossref_primary_10_1002_dmrr_3387
crossref_primary_10_1186_s13098_022_00857_2
crossref_primary_10_3389_fphys_2021_749731
crossref_primary_10_12968_bjhc_2020_0139
crossref_primary_10_1186_s12890_024_03424_9
crossref_primary_10_1016_j_numecd_2020_05_013
crossref_primary_10_4103_jfmpc_jfmpc_973_21
crossref_primary_10_20960_nh_03469
crossref_primary_10_1002_dmrr_3378
crossref_primary_10_1016_j_nut_2021_111408
crossref_primary_10_1136_bmjopen_2021_049650
crossref_primary_10_4103_jnsm_jnsm_107_20
crossref_primary_10_1016_j_arr_2021_101494
crossref_primary_10_1016_j_diabres_2025_112100
crossref_primary_10_4093_dmj_2020_0236
crossref_primary_10_26599_FSHW_2023_9250052
crossref_primary_10_3389_fendo_2023_1167087
crossref_primary_10_1186_s12882_021_02369_z
crossref_primary_10_1186_s12913_023_09158_4
crossref_primary_10_36106_gjra_0200127
crossref_primary_10_37349_ei_2021_00025
crossref_primary_10_1111_imj_15937
crossref_primary_10_1007_s10787_023_01308_8
crossref_primary_10_1161_HYPERTENSIONAHA_120_15289
crossref_primary_10_17116_profmed20232611153
crossref_primary_10_3390_cells10061412
crossref_primary_10_1007_s00540_021_02965_1
crossref_primary_10_1007_s12020_023_03337_3
crossref_primary_10_3389_fendo_2025_1467303
crossref_primary_10_3390_jcm9113635
crossref_primary_10_18632_aging_103344
crossref_primary_10_1016_S2213_8587_20_30381_8
crossref_primary_10_1016_j_artere_2021_04_004
crossref_primary_10_3389_fendo_2021_649525
crossref_primary_10_1038_s41598_021_02297_w
crossref_primary_10_1007_s40200_020_00701_2
crossref_primary_10_3389_fphys_2022_836480
crossref_primary_10_3390_v14092067
crossref_primary_10_1016_j_celrep_2022_110508
crossref_primary_10_1111_dom_14170
crossref_primary_10_1186_s12933_020_01140_2
crossref_primary_10_17826_cumj_1434628
crossref_primary_10_1007_s12035_020_02074_2
crossref_primary_10_1177_1060028021999473
crossref_primary_10_1007_s40200_021_00844_w
crossref_primary_10_1093_ckj_sfaa160
crossref_primary_10_1155_2021_7394378
crossref_primary_10_3233_JRS_227012
crossref_primary_10_1146_annurev_med_042220_011857
crossref_primary_10_1016_j_diabres_2025_112118
crossref_primary_10_1186_s13098_023_01104_y
crossref_primary_10_1016_j_clinimag_2022_12_002
crossref_primary_10_1177_20420188211054686
crossref_primary_10_1016_j_addr_2021_113848
crossref_primary_10_1016_S2213_8587_20_30272_2
crossref_primary_10_1111_imm_13706
crossref_primary_10_1002_dmrr_3393
crossref_primary_10_1002_dmrr_3398
crossref_primary_10_6065_apem_2244150_075
crossref_primary_10_1136_bmjgast_2020_000568
crossref_primary_10_1016_S0140_6736_20_32378_3
crossref_primary_10_1111_dom_14184
Cites_doi 10.1016/S2213-8587(18)30048-2
10.1111/jth.12190
10.1038/nm1267
10.1007/s00134-003-1961-2
10.1016/j.cell.2020.02.052
10.1172/jci.insight.131774
10.1136/bmjopen-2013-002847
10.1016/S0140-6736(20)30251-8
10.1152/physrev.00065.2017
10.7326/M16-2607
10.1002/dmrr.3159
10.1093/pan/mpl013
10.1001/jama.2018.21554
10.1056/NEJMoa2002032
10.1016/S0140-6736(20)30183-5
10.1056/NEJMoa2001017
10.1056/NEJMoa052521
10.1001/jama.2020.1585
10.18637/jss.v042.i07
10.1001/jama.289.21.JOC30885
10.1001/jama.2020.2648
10.1111/imm.12762
10.1017/S0950268818002923
10.1136/bmj.l5887
10.1111/all.14238
10.1198/1061860031365
10.1097/EDE.0000000000000864
10.1016/S0140-6736(20)30566-3
10.1111/j.1464-5491.2006.01861.x
10.1161/01.CIR.0000021122.63813.32
10.1016/S0140-6736(20)30211-7
10.1001/jama.2017.7596
10.3390/jcm9020575
ContentType Journal Article
Copyright 2020 Elsevier Inc.
Copyright © 2020 Elsevier Inc. All rights reserved.
2020 Elsevier Inc. 2020 Elsevier Inc.
Copyright_xml – notice: 2020 Elsevier Inc.
– notice: Copyright © 2020 Elsevier Inc. All rights reserved.
– notice: 2020 Elsevier Inc. 2020 Elsevier Inc.
DBID 6I.
AAFTH
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
5PM
DOI 10.1016/j.cmet.2020.04.021
DatabaseName ScienceDirect Open Access Titles
Elsevier:ScienceDirect:Open Access
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
PubMed Central (Full Participant titles)
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
DatabaseTitleList MEDLINE - Academic


MEDLINE
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
EISSN 1932-7420
EndPage 1077.e3
ExternalDocumentID PMC7252168
32369736
10_1016_j_cmet_2020_04_021
S1550413120302382
Genre Research Support, Non-U.S. Gov't
Multicenter Study
Journal Article
GroupedDBID ---
--K
0R~
1~5
29B
2WC
4.4
457
4G.
53G
5GY
62-
6I.
6J9
7-5
AACTN
AAEDW
AAFTH
AAIAV
AAKRW
AAKUH
AALRI
AAUCE
AAVLU
AAXUO
ABJNI
ABMAC
ABMWF
ABVKL
ACGFO
ACGFS
ADBBV
ADEZE
ADJPV
AEFWE
AENEX
AEXQZ
AFTJW
AGKMS
AITUG
ALKID
ALMA_UNASSIGNED_HOLDINGS
AMRAJ
ASPBG
AVWKF
AZFZN
BAWUL
CS3
DIK
DU5
E3Z
EBS
F5P
FCP
FDB
FEDTE
FIRID
HVGLF
IHE
IXB
J1W
JIG
M3Z
M41
O-L
O9-
OK1
P2P
RCE
ROL
RPZ
SES
SSZ
TR2
UNMZH
WQ6
ZA5
AAEDT
AAIKJ
AAMRU
AAYWO
AAYXX
ABDGV
ACVFH
ADCNI
ADVLN
AEUPX
AFPUW
AGCQF
AGHFR
AIGII
AKAPO
AKBMS
AKRWK
AKYEP
APXCP
CITATION
EJD
HZ~
OZT
RIG
CGR
CUY
CVF
ECM
EFKBS
EIF
NPM
7X8
5PM
ID FETCH-LOGICAL-c483t-9e6c295d1bf4672354838e31b909bbca3c4b7171daa53992bb24370b7188a2c53
IEDL.DBID IXB
ISSN 1550-4131
1932-7420
IngestDate Thu Aug 21 18:28:37 EDT 2025
Thu Jul 10 23:20:28 EDT 2025
Mon Jul 21 05:40:11 EDT 2025
Tue Jul 01 03:58:19 EDT 2025
Thu Apr 24 23:04:11 EDT 2025
Fri Feb 23 02:42:11 EST 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 6
Keywords COVID-19
mortality
SARS-CoV-2
diabetes mellitus
blood glucose control
Language English
License This article is made available under the Elsevier license.
Copyright © 2020 Elsevier Inc. All rights reserved.
Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c483t-9e6c295d1bf4672354838e31b909bbca3c4b7171daa53992bb24370b7188a2c53
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Lead Contact
These authors contributed equally
OpenAccessLink https://www.sciencedirect.com/science/article/pii/S1550413120302382
PMID 32369736
PQID 2399253357
PQPubID 23479
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_7252168
proquest_miscellaneous_2399253357
pubmed_primary_32369736
crossref_citationtrail_10_1016_j_cmet_2020_04_021
crossref_primary_10_1016_j_cmet_2020_04_021
elsevier_sciencedirect_doi_10_1016_j_cmet_2020_04_021
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2020-06-02
PublicationDateYYYYMMDD 2020-06-02
PublicationDate_xml – month: 06
  year: 2020
  text: 2020-06-02
  day: 02
PublicationDecade 2020
PublicationPlace United States
PublicationPlace_xml – name: United States
PublicationTitle Cell metabolism
PublicationTitleAlternate Cell Metab
PublicationYear 2020
Publisher Elsevier Inc
Publisher_xml – name: Elsevier Inc
References Ho, Imai, King, Stuart (bib39) 2007; 15
(bib22) 2020
Huang, Wang, Li, Ren, Zhao, Hu, Zhang, Fan, Xu, Gu (bib14) 2020; 395
Therneau, Pankratz (bib38) 2003; 12
Chen, Zhou, Dong, Qu, Gong, Han, Qiu, Wang, Liu, Wei (bib5) 2020; 395
Hoffmann, Kleine-Weber, Schroeder, Krüger, Herrler, Erichsen, Schiergens, Herrler, Wu, Nitsche (bib13) 2020; 181
Wang, Hu, Hu, Zhu, Liu, Zhang, Wang, Xiang, Cheng, Xiong (bib29) 2020
Bornstein, Rubino, Khunti, Mingrone, Hopkins, Birkenfeld, Boehm, Amiel, Holt, Skyler (bib3) 2020
Mathur, Ding, Riddell, VanderWeele (bib21) 2018; 29
VanderWeele, Ding (bib26) 2017; 167
Haneuse, VanderWeele, Arterburn (bib12) 2019; 321
Booth, Matukas, Tomlinson, Rachlis, Rose, Dwosh, Walmsley, Mazzulli, Avendano, Derkach (bib2) 2003; 289
Forbes, Murrells, Mulnier, Sinclair (bib8) 2018; 6
Kumar Nathella, Babu (bib18) 2017; 152
(bib6) 2018; 38
Guan, Ni, Hu, Liang, Ou, He, Liu, Shan, Lei, Hui (bib11) 2020
Gando, Wada, Thachil (bib10) 2013; 11
Zhang, Dong, Cao, Yuan, Yang, Yan, Akdis, Gao (bib34) 2020
Fuso, Pitocco, Antonelli-Incalzi (bib9) 2019; 35
Yang, Feng, Yuan, Yuan, Fu, Wu, Sun, Yang, Zhang, Wang (bib33) 2006; 23
Zhang, Zhu, Cai, Lei, Qin, Xie, Liu, Zhao, Huang, Lin (bib35) 2020
Rodriguez-Gutierrez, Gonzalez-Gonzalez, Zuñiga-Hernandez, McCoy (bib24) 2019; 367
Van den Berghe, Wilmer, Hermans, Meersseman, Wouters, Milants, Van Wijngaerden, Bobbaers, Bouillon (bib25) 2006; 354
Zhu, Zhang, Wang, Li, Yang, Song, Zhao, Huang, Shi, Lu (bib37) 2020; 382
Sekhon (bib40) 2011; 42
Kellum, Lameire, Aspelin, Barsoum, Burdmann, Goldstein, Herzog, Joannidis, Kribben, Levey (bib15) 2012; 2
Wang, Gao, Zhang, Huang, Zhang, Deng, Li, Zhao, Qin, Jin (bib28) 2017; 317
Deng, Peng (bib7) 2020; 9
Marrone, Vaccaro, Biolato, Miele, Liguori, Araneo, Ponziani, Mores, Gasbarrini, Grieco (bib20) 2017; 21
Wu, McGoogan (bib31) 2020
Xu, Liu, Li (bib32) 2019; 99
Zhou, Yu, Du, Fan, Liu, Liu, Xiang, Wang, Song, Gu (bib36) 2020; 395
Kulcsar, Coleman, Beck, Frieman (bib17) 2019; 4
Alqahtani, Aleanizy, Ali El Hadi Mohamed, Alanazi, Mohamed, Alrasheed, Abanmy, Alhawassi (bib1) 2018; 147
Candido, Jandeleit-Dahm, Cao, Nesteroff, Burns, Twigg, Dilley, Cooper, Allen (bib4) 2002; 106
Philips, Meguer, Redman, Baker (bib23) 2003; 29
Lu, Zhao, Li, Niu, Yang, Wu, Wang, Song, Huang, Zhu (bib19) 2020; 395
Waljee, Mukherjee, Singal, Zhang, Warren, Balis, Marrero, Zhu, Higgins (bib27) 2013; 3
(bib30) 2020
Kuba, Imai, Rao, Gao, Guo, Guan, Huan, Yang, Zhang, Deng (bib16) 2005; 11
Ho (10.1016/j.cmet.2020.04.021_bib39) 2007; 15
Zhang (10.1016/j.cmet.2020.04.021_bib34) 2020
Kuba (10.1016/j.cmet.2020.04.021_bib16) 2005; 11
Alqahtani (10.1016/j.cmet.2020.04.021_bib1) 2018; 147
Van den Berghe (10.1016/j.cmet.2020.04.021_bib25) 2006; 354
Waljee (10.1016/j.cmet.2020.04.021_bib27) 2013; 3
Xu (10.1016/j.cmet.2020.04.021_bib32) 2019; 99
Yang (10.1016/j.cmet.2020.04.021_bib33) 2006; 23
Philips (10.1016/j.cmet.2020.04.021_bib23) 2003; 29
Haneuse (10.1016/j.cmet.2020.04.021_bib12) 2019; 321
Marrone (10.1016/j.cmet.2020.04.021_bib20) 2017; 21
Wu (10.1016/j.cmet.2020.04.021_bib31) 2020
Zhou (10.1016/j.cmet.2020.04.021_bib36) 2020; 395
Candido (10.1016/j.cmet.2020.04.021_bib4) 2002; 106
Lu (10.1016/j.cmet.2020.04.021_bib19) 2020; 395
Mathur (10.1016/j.cmet.2020.04.021_bib21) 2018; 29
Guan (10.1016/j.cmet.2020.04.021_bib11) 2020
Chen (10.1016/j.cmet.2020.04.021_bib5) 2020; 395
Fuso (10.1016/j.cmet.2020.04.021_bib9) 2019; 35
(10.1016/j.cmet.2020.04.021_bib6) 2018; 38
Rodriguez-Gutierrez (10.1016/j.cmet.2020.04.021_bib24) 2019; 367
Bornstein (10.1016/j.cmet.2020.04.021_bib3) 2020
Wang (10.1016/j.cmet.2020.04.021_bib29) 2020
Gando (10.1016/j.cmet.2020.04.021_bib10) 2013; 11
Therneau (10.1016/j.cmet.2020.04.021_bib38) 2003; 12
Zhang (10.1016/j.cmet.2020.04.021_bib35) 2020
Zhu (10.1016/j.cmet.2020.04.021_bib37) 2020; 382
Deng (10.1016/j.cmet.2020.04.021_bib7) 2020; 9
Huang (10.1016/j.cmet.2020.04.021_bib14) 2020; 395
Booth (10.1016/j.cmet.2020.04.021_bib2) 2003; 289
(10.1016/j.cmet.2020.04.021_bib30) 2020
Kulcsar (10.1016/j.cmet.2020.04.021_bib17) 2019; 4
(10.1016/j.cmet.2020.04.021_bib22) 2020
Kumar Nathella (10.1016/j.cmet.2020.04.021_bib18) 2017; 152
VanderWeele (10.1016/j.cmet.2020.04.021_bib26) 2017; 167
Wang (10.1016/j.cmet.2020.04.021_bib28) 2017; 317
Forbes (10.1016/j.cmet.2020.04.021_bib8) 2018; 6
Hoffmann (10.1016/j.cmet.2020.04.021_bib13) 2020; 181
Sekhon (10.1016/j.cmet.2020.04.021_bib40) 2011; 42
Kellum (10.1016/j.cmet.2020.04.021_bib15) 2012; 2
33037170 - J Postgrad Med. 2020 Oct-Dec;66(4):179-181. doi: 10.4103/jpgm.JPGM_602_20
References_xml – volume: 21
  start-page: 122
  year: 2017
  end-page: 134
  ident: bib20
  article-title: Drug-induced liver injury 2017: the diagnosis is not easy but always to keep in mind
  publication-title: Eur. Rev. Med. Pharmacol. Sci.
– volume: 181
  start-page: 271
  year: 2020
  end-page: 280.e8
  ident: bib13
  article-title: SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor
  publication-title: Cell
– volume: 367
  start-page: l5887
  year: 2019
  ident: bib24
  article-title: Benefits and harms of intensive glycemic control in patients with type 2 diabetes
  publication-title: BMJ
– volume: 152
  start-page: 13
  year: 2017
  end-page: 24
  ident: bib18
  article-title: Influence of diabetes mellitus on immunity to human tuberculosis
  publication-title: Immunology
– volume: 12
  start-page: 156
  year: 2003
  end-page: 175
  ident: bib38
  article-title: Penalized survival models and frailty
  publication-title: J. Comput. Graph. Stat.
– volume: 6
  start-page: 476
  year: 2018
  end-page: 486
  ident: bib8
  article-title: Mean HbA
  publication-title: Lancet Diabetes Endocrinol.
– year: 2020
  ident: bib3
  article-title: Practical recommendations for the management of diabetes in patients with COVID-19
  publication-title: Lancet Diabetes Endocrinol.
– volume: 395
  start-page: 565
  year: 2020
  end-page: 574
  ident: bib19
  article-title: Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
  publication-title: Lancet
– volume: 9
  start-page: E575
  year: 2020
  ident: bib7
  article-title: Characteristics of and public health responses to the coronavirus disease 2019 outbreak in China
  publication-title: J. Clin. Med.
– year: 2020
  ident: bib30
  article-title: Laboratory testing for 2019 novel coronavirus (2019-nCoV) in suspected human cases: interim guidance
– volume: 167
  start-page: 268
  year: 2017
  end-page: 274
  ident: bib26
  article-title: Sensitivity analysis in observational research: introducing the E-value
  publication-title: Ann. Intern. Med.
– volume: 395
  start-page: 507
  year: 2020
  end-page: 513
  ident: bib5
  article-title: Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
  publication-title: Lancet
– volume: 4
  start-page: 131774
  year: 2019
  ident: bib17
  article-title: Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection
  publication-title: JCI Insight
– volume: 23
  start-page: 623
  year: 2006
  end-page: 628
  ident: bib33
  article-title: Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS
  publication-title: Diabet. Med.
– volume: 15
  start-page: 199
  year: 2007
  end-page: 236
  ident: bib39
  article-title: Matching as nonparametric preprocessing for reducing model dependence in parametric causal inference
  publication-title: Polit. Anal.
– volume: 395
  start-page: 497
  year: 2020
  end-page: 506
  ident: bib14
  article-title: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
  publication-title: Lancet
– volume: 395
  start-page: 1054
  year: 2020
  end-page: 1062
  ident: bib36
  article-title: Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
  publication-title: Lancet
– volume: 35
  start-page: e3159
  year: 2019
  ident: bib9
  article-title: Diabetic lung, an underrated complication from restrictive functional pattern to pulmonary hypertension
  publication-title: Diabetes Metab. Res. Rev.
– volume: 3
  start-page: e002847
  year: 2013
  ident: bib27
  article-title: Comparison of imputation methods for missing laboratory data in medicine
  publication-title: BMJ Open
– year: 2020
  ident: bib29
  article-title: Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China
  publication-title: JAMA
– year: 2020
  ident: bib22
  article-title: New Coronavirus Pneumonia Prevention and Control Program
– volume: 354
  start-page: 449
  year: 2006
  end-page: 461
  ident: bib25
  article-title: Intensive insulin therapy in the medical ICU
  publication-title: N. Engl. J. Med.
– volume: 11
  start-page: 875
  year: 2005
  end-page: 879
  ident: bib16
  article-title: A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury
  publication-title: Nat. Med.
– year: 2020
  ident: bib11
  article-title: Clinical characteristics of coronavirus disease 2019 in China
  publication-title: N. Engl. J. Med.
– volume: 2
  start-page: 1
  year: 2012
  end-page: 138
  ident: bib15
  article-title: Kidney disease: improving global outcomes (KDIGO) acute kidney injury work group. KDIGO clinical practice guideline for acute kidney injury
  publication-title: Kidney Int. Suppl.
– volume: 289
  start-page: 2801
  year: 2003
  end-page: 2809
  ident: bib2
  article-title: Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area
  publication-title: JAMA
– volume: 321
  start-page: 602
  year: 2019
  end-page: 603
  ident: bib12
  article-title: Using the E-value to assess the potential effect of unmeasured confounding in observational studies
  publication-title: JAMA
– year: 2020
  ident: bib34
  article-title: Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China
  publication-title: Allergy
– volume: 147
  start-page: e35
  year: 2018
  ident: bib1
  article-title: Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: a retrospective study
  publication-title: Epidemiol. Infect.
– volume: 29
  start-page: e45
  year: 2018
  end-page: e47
  ident: bib21
  article-title: Web site and R package for computing E-values
  publication-title: Epidemiology
– volume: 38
  start-page: 53
  year: 2018
  ident: bib6
  article-title: Guidelines for the prevention and control of type 2 diabetes in China (2017 Edition)
  publication-title: Zhongguo Shiyong Neike Zazhi
– year: 2020
  ident: bib35
  article-title: Association of inpatient use of angiotensin converting enzyme inhibitors and angiotensin II receptor blockers with mortality among patients with hypertension hospitalized with COVID-19
  publication-title: Circ. Res.
– year: 2020
  ident: bib31
  article-title: Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention
  publication-title: JAMA
– volume: 11
  start-page: 826
  year: 2013
  end-page: 835
  ident: bib10
  article-title: Differentiating disseminated intravascular coagulation (DIC) with the fibrinolytic phenotype from coagulopathy of trauma and acute coagulopathy of trauma-shock (COT/ACOTS)
  publication-title: J. Thromb. Haemost.
– volume: 382
  start-page: 727
  year: 2020
  end-page: 733
  ident: bib37
  article-title: A novel coronavirus from patients with pneumonia in China, 2019
  publication-title: N. Engl. J. Med.
– volume: 29
  start-page: 2204
  year: 2003
  end-page: 2210
  ident: bib23
  article-title: Factors determining the appearance of glucose in upper and lower respiratory tract secretions
  publication-title: Intensive Care Med.
– volume: 317
  start-page: 2515
  year: 2017
  end-page: 2523
  ident: bib28
  article-title: Prevalence and ethnic pattern of diabetes and prediabetes in China in 2013
  publication-title: JAMA
– volume: 106
  start-page: 246
  year: 2002
  end-page: 253
  ident: bib4
  article-title: Prevention of accelerated atherosclerosis by angiotensin-converting enzyme inhibition in diabetic apolipoprotein E-deficient mice
  publication-title: Circulation
– volume: 99
  start-page: 893
  year: 2019
  end-page: 948
  ident: bib32
  article-title: Innate immune signaling and its role in metabolic and cardiovascular diseases
  publication-title: Physiol. Rev.
– volume: 42
  year: 2011
  ident: bib40
  article-title: Multivariate and propensity score matching software with automated balance optimization: the matching package for R
  publication-title: J. Stat. Softw.
– volume: 6
  start-page: 476
  year: 2018
  ident: 10.1016/j.cmet.2020.04.021_bib8
  article-title: Mean HbA1c, HbA1c variability, and mortality in people with diabetes aged 70 years and older: a retrospective cohort study
  publication-title: Lancet Diabetes Endocrinol.
  doi: 10.1016/S2213-8587(18)30048-2
– volume: 11
  start-page: 826
  year: 2013
  ident: 10.1016/j.cmet.2020.04.021_bib10
  article-title: Differentiating disseminated intravascular coagulation (DIC) with the fibrinolytic phenotype from coagulopathy of trauma and acute coagulopathy of trauma-shock (COT/ACOTS)
  publication-title: J. Thromb. Haemost.
  doi: 10.1111/jth.12190
– volume: 11
  start-page: 875
  year: 2005
  ident: 10.1016/j.cmet.2020.04.021_bib16
  article-title: A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury
  publication-title: Nat. Med.
  doi: 10.1038/nm1267
– volume: 29
  start-page: 2204
  year: 2003
  ident: 10.1016/j.cmet.2020.04.021_bib23
  article-title: Factors determining the appearance of glucose in upper and lower respiratory tract secretions
  publication-title: Intensive Care Med.
  doi: 10.1007/s00134-003-1961-2
– volume: 181
  start-page: 271
  year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib13
  article-title: SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor
  publication-title: Cell
  doi: 10.1016/j.cell.2020.02.052
– volume: 4
  start-page: 131774
  year: 2019
  ident: 10.1016/j.cmet.2020.04.021_bib17
  article-title: Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection
  publication-title: JCI Insight
  doi: 10.1172/jci.insight.131774
– volume: 3
  start-page: e002847
  year: 2013
  ident: 10.1016/j.cmet.2020.04.021_bib27
  article-title: Comparison of imputation methods for missing laboratory data in medicine
  publication-title: BMJ Open
  doi: 10.1136/bmjopen-2013-002847
– volume: 395
  start-page: 565
  year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib19
  article-title: Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
  publication-title: Lancet
  doi: 10.1016/S0140-6736(20)30251-8
– volume: 99
  start-page: 893
  year: 2019
  ident: 10.1016/j.cmet.2020.04.021_bib32
  article-title: Innate immune signaling and its role in metabolic and cardiovascular diseases
  publication-title: Physiol. Rev.
  doi: 10.1152/physrev.00065.2017
– volume: 21
  start-page: 122
  issue: Suppl
  year: 2017
  ident: 10.1016/j.cmet.2020.04.021_bib20
  article-title: Drug-induced liver injury 2017: the diagnosis is not easy but always to keep in mind
  publication-title: Eur. Rev. Med. Pharmacol. Sci.
– volume: 167
  start-page: 268
  year: 2017
  ident: 10.1016/j.cmet.2020.04.021_bib26
  article-title: Sensitivity analysis in observational research: introducing the E-value
  publication-title: Ann. Intern. Med.
  doi: 10.7326/M16-2607
– year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib35
  article-title: Association of inpatient use of angiotensin converting enzyme inhibitors and angiotensin II receptor blockers with mortality among patients with hypertension hospitalized with COVID-19
  publication-title: Circ. Res.
– volume: 38
  start-page: 53
  year: 2018
  ident: 10.1016/j.cmet.2020.04.021_bib6
  article-title: Guidelines for the prevention and control of type 2 diabetes in China (2017 Edition)
  publication-title: Zhongguo Shiyong Neike Zazhi
– volume: 35
  start-page: e3159
  year: 2019
  ident: 10.1016/j.cmet.2020.04.021_bib9
  article-title: Diabetic lung, an underrated complication from restrictive functional pattern to pulmonary hypertension
  publication-title: Diabetes Metab. Res. Rev.
  doi: 10.1002/dmrr.3159
– volume: 15
  start-page: 199
  year: 2007
  ident: 10.1016/j.cmet.2020.04.021_bib39
  article-title: Matching as nonparametric preprocessing for reducing model dependence in parametric causal inference
  publication-title: Polit. Anal.
  doi: 10.1093/pan/mpl013
– volume: 321
  start-page: 602
  year: 2019
  ident: 10.1016/j.cmet.2020.04.021_bib12
  article-title: Using the E-value to assess the potential effect of unmeasured confounding in observational studies
  publication-title: JAMA
  doi: 10.1001/jama.2018.21554
– year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib30
– year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib22
– year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib11
  article-title: Clinical characteristics of coronavirus disease 2019 in China
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMoa2002032
– volume: 395
  start-page: 497
  year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib14
  article-title: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
  publication-title: Lancet
  doi: 10.1016/S0140-6736(20)30183-5
– volume: 382
  start-page: 727
  year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib37
  article-title: A novel coronavirus from patients with pneumonia in China, 2019
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMoa2001017
– volume: 354
  start-page: 449
  year: 2006
  ident: 10.1016/j.cmet.2020.04.021_bib25
  article-title: Intensive insulin therapy in the medical ICU
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMoa052521
– year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib29
  article-title: Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China
  publication-title: JAMA
  doi: 10.1001/jama.2020.1585
– volume: 42
  year: 2011
  ident: 10.1016/j.cmet.2020.04.021_bib40
  article-title: Multivariate and propensity score matching software with automated balance optimization: the matching package for R
  publication-title: J. Stat. Softw.
  doi: 10.18637/jss.v042.i07
– volume: 2
  start-page: 1
  year: 2012
  ident: 10.1016/j.cmet.2020.04.021_bib15
  article-title: Kidney disease: improving global outcomes (KDIGO) acute kidney injury work group. KDIGO clinical practice guideline for acute kidney injury
  publication-title: Kidney Int. Suppl.
– year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib3
  article-title: Practical recommendations for the management of diabetes in patients with COVID-19
  publication-title: Lancet Diabetes Endocrinol.
– volume: 289
  start-page: 2801
  year: 2003
  ident: 10.1016/j.cmet.2020.04.021_bib2
  article-title: Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area
  publication-title: JAMA
  doi: 10.1001/jama.289.21.JOC30885
– year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib31
  article-title: Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention
  publication-title: JAMA
  doi: 10.1001/jama.2020.2648
– volume: 152
  start-page: 13
  year: 2017
  ident: 10.1016/j.cmet.2020.04.021_bib18
  article-title: Influence of diabetes mellitus on immunity to human tuberculosis
  publication-title: Immunology
  doi: 10.1111/imm.12762
– volume: 147
  start-page: e35
  year: 2018
  ident: 10.1016/j.cmet.2020.04.021_bib1
  article-title: Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: a retrospective study
  publication-title: Epidemiol. Infect.
  doi: 10.1017/S0950268818002923
– volume: 367
  start-page: l5887
  year: 2019
  ident: 10.1016/j.cmet.2020.04.021_bib24
  article-title: Benefits and harms of intensive glycemic control in patients with type 2 diabetes
  publication-title: BMJ
  doi: 10.1136/bmj.l5887
– year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib34
  article-title: Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China
  publication-title: Allergy
  doi: 10.1111/all.14238
– volume: 12
  start-page: 156
  year: 2003
  ident: 10.1016/j.cmet.2020.04.021_bib38
  article-title: Penalized survival models and frailty
  publication-title: J. Comput. Graph. Stat.
  doi: 10.1198/1061860031365
– volume: 29
  start-page: e45
  year: 2018
  ident: 10.1016/j.cmet.2020.04.021_bib21
  article-title: Web site and R package for computing E-values
  publication-title: Epidemiology
  doi: 10.1097/EDE.0000000000000864
– volume: 395
  start-page: 1054
  year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib36
  article-title: Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
  publication-title: Lancet
  doi: 10.1016/S0140-6736(20)30566-3
– volume: 23
  start-page: 623
  year: 2006
  ident: 10.1016/j.cmet.2020.04.021_bib33
  article-title: Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS
  publication-title: Diabet. Med.
  doi: 10.1111/j.1464-5491.2006.01861.x
– volume: 106
  start-page: 246
  year: 2002
  ident: 10.1016/j.cmet.2020.04.021_bib4
  article-title: Prevention of accelerated atherosclerosis by angiotensin-converting enzyme inhibition in diabetic apolipoprotein E-deficient mice
  publication-title: Circulation
  doi: 10.1161/01.CIR.0000021122.63813.32
– volume: 395
  start-page: 507
  year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib5
  article-title: Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
  publication-title: Lancet
  doi: 10.1016/S0140-6736(20)30211-7
– volume: 317
  start-page: 2515
  year: 2017
  ident: 10.1016/j.cmet.2020.04.021_bib28
  article-title: Prevalence and ethnic pattern of diabetes and prediabetes in China in 2013
  publication-title: JAMA
  doi: 10.1001/jama.2017.7596
– volume: 9
  start-page: E575
  year: 2020
  ident: 10.1016/j.cmet.2020.04.021_bib7
  article-title: Characteristics of and public health responses to the coronavirus disease 2019 outbreak in China
  publication-title: J. Clin. Med.
  doi: 10.3390/jcm9020575
– reference: 33037170 - J Postgrad Med. 2020 Oct-Dec;66(4):179-181. doi: 10.4103/jpgm.JPGM_602_20
SSID ssj0036393
Score 2.7267227
Snippet Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of blood glucose (BG) control on the degree of required medical interventions and...
SourceID pubmedcentral
proquest
pubmed
crossref
elsevier
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 1068
SubjectTerms Aged
Betacoronavirus - pathogenicity
Blood Glucose - analysis
blood glucose control
Clinical and Translational Report
Coronavirus Infections - complications
Coronavirus Infections - mortality
Coronavirus Infections - pathology
COVID-19
diabetes mellitus
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - complications
Disease Susceptibility - pathology
Female
Glycemic Index - physiology
Hospitalization - statistics & numerical data
Humans
Hyperglycemia - blood
Hyperglycemia - complications
Hypoglycemic Agents - therapeutic use
Longitudinal Studies
Male
Middle Aged
mortality
Multiple Organ Failure - complications
Multiple Organ Failure - mortality
Pandemics
Pneumonia, Viral - complications
Pneumonia, Viral - mortality
Pneumonia, Viral - pathology
Retrospective Studies
SARS-CoV-2
Title Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes
URI https://dx.doi.org/10.1016/j.cmet.2020.04.021
https://www.ncbi.nlm.nih.gov/pubmed/32369736
https://www.proquest.com/docview/2399253357
https://pubmed.ncbi.nlm.nih.gov/PMC7252168
Volume 31
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3Nb9MwFLeqSUhcJj5HYSAjcUNWYztx4uNaGAUJOgmGerPsxBadRjr147D_fu_ZSbWC6IFjnOfIes95H8nv_UzIuyxwWTbaszIEzyBeS2Y5VClCWaV9VgaeYe_w129qepl_mRfzAZn0vTAIq-x8f_Lp0Vt3I6NOm6ObxWL0HZNrcMHwZDz4pkI_LPMqNvHNx703lhCBI8gehBlKd40zCeNV__aIpxRZpDsV_F_B6e_k808M5b2gdP6IHHfZJD1LC35MBr59Qh6k8yVvn5Lre8qny0DHiFKnnxJKnU4SSp3atqGz7QY04Nd00dKLRLW6pviNlk5mPz9_YFxHsYuVZ8idiVhpiiUsFbTD1Kyfkcvzjz8mU9Ydr8BqUNOGaa9qoYuGuwDeUkioXWTlJXc6087VVta5g2KPN9ZG-lrnkLwwg7GqsqIu5HNy1C5b_4LQPAu2CpY7D9VdoYNueGlDrXSlmkK5ckh4r1dTd9zjeATGtelBZlcGbWHQFibLDdhiSN7v5twk5o2D0kVvLrO3fwyEhoPz3va2NfBi4d8S2_rldm2w6VdAMlzA6k-SrXfrkEIqXUo1JOXeLtgJIGn3_p128SuSd5cCEiZVvfzP9b4iD_EqgtXEKTnarLb-NaRFG_cm7vs7VC8J5g
linkProvider Elsevier
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELaqIgQXRHl1gYKRuCFrYzux4yPdtuxCXxIt2ptlJ7ZYVLJVd_fAv2cmTlZdED1wjceR5bHnkXzzDSHvs8ilrk1gOsbAwF9L5jhkKUI5ZUKmI8-wdvjkVI0v88_TYrpFRn0tDMIqO9ufbHprrbsnw243h9ez2fArBtdgguHN2PimBDt8D6IBjf0bJtP93hxLcMEtyh6kGYp3lTMJ5FX9DAioFFnLdyr4v7zT39HnnyDKW17p6DF51IWT9GNa8Q7ZCs0Tcj81mPz1lFzd2n06j3QfYer0U4Kp01GCqVPX1PRstYQtCAs6a-h54lpdUPxIS0dn3yYHjJtW7PwmMCTPRLA0xRyWCtqBahbPyOXR4cVozLr-CqzKS7lkJqhKmKLmPoK5FBKSF1kGyb3JjPeVk1XuIdvjtXMtf633yF6YwbOydKIq5HOy3cybsEtonkVXRsd9gPSuMNHUXLtYKVOqulBeDwjv99VWHfk49sC4sj3K7IdFXVjUhc1yC7oYkA_rOdeJeuNO6aJXl904QBZ8w53z3vW6tXCz8HeJa8J8tbBY9SsgGi5g9S-SrtfrkEIqo6UaEL1xCtYCyNq9OdLMvrfs3VpAxKTKl_-53rfkwfji5NgeT06_vCIPcaRFronXZHt5swp7ECMt_Zv2DvwGsLgNBQ
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Association+of+Blood+Glucose+Control+and+Outcomes+in+Patients+with+COVID-19+and+Pre-existing+Type+2+Diabetes&rft.jtitle=Cell+metabolism&rft.au=Zhu%2C+Lihua&rft.au=She%2C+Zhi-Gang&rft.au=Cheng%2C+Xu&rft.au=Qin%2C+Juan-Juan&rft.date=2020-06-02&rft.pub=Elsevier+Inc&rft.issn=1550-4131&rft.eissn=1932-7420&rft.volume=31&rft.issue=6&rft.spage=1068&rft.epage=1077.e3&rft_id=info:doi/10.1016%2Fj.cmet.2020.04.021&rft_id=info%3Apmid%2F32369736&rft.externalDocID=PMC7252168
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1550-4131&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1550-4131&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1550-4131&client=summon