Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition - Greaney, Allison J.; Starr, Tyler N.; Gilchuk, Pavlo; Zost, Seth J.; Binshtein, Elad; Loes, Andrea N.; Hilton, Sarah K.; Huddleston, John; Eguia, Rachel; Crawford, Katharine H.D.; Dingens, Adam S.; Nargi, Rachel S.; et al. (Cell host & microbe, 2021)
Keywords: Angiotensin-Converting Enzyme 2 - chemistry; Angiotensin-Converting Enzyme 2 - metabolism; Antibodies, Monoclonal - immunology; Antibodies, Neutralizing - immunology; antibody escape; antigenic evolution; Binding Sites; deep mutational scanning; Epitopes - immunology; Gene Library; High-Throughput Nucleotide Sequencing; Humans; Protein Domains; Saccharomyces cerevisiae - genetics; SARS-CoV-2; SARS-CoV-2 - genetics; SARS-CoV-2 - immunology; Spike Glycoprotein, Coronavirus - chemistry; Spike Glycoprotein, Coronavirus - genetics; Spike Glycoprotein, Coronavirus - immunology; Spike Glycoprotein, Coronavirus - metabolism; antibody escape; SARS-CoV-2; deep mutational scanning; antigenic evolution