Food consumption and advanced β cell autoimmunity in young children with HLA-conferred susceptibility to type 1 diabetes: a nested case-control design

• Published in: The American journal of clinical nutrition Vol. 95; no. 2; pp. 471 - 478
• Main Authors: Virtanen, Suvi M, Nevalainen, Jaakko, Kronberg-Kippilä, Carina, Ahonen, Suvi, Tapanainen, Heli, Uusitalo, Liisa, Takkinen, Hanna-Mari, Niinistö, Sari, Ovaskainen, Marja-Leena, Kenward, Michael G, Veijola, Riitta, Ilonen, Jorma, Simell, Olli, Knip, Mikael
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Elsevier Inc 01.02.2012; American Society for Nutrition
• Subjects: adverse effects; Animals; Autoantibodies; Autoimmunity; Biological and medical sciences; Case-Control Studies; Cattle; Child; child development; Child, Preschool; childhood; dairy protein; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 1 - immunology; Diet; Diet - adverse effects; Diet Records; Dietary Fats; Dietary Fats - adverse effects; Dietary Fats - immunology; Dietary Proteins; Dietary Proteins - adverse effects; Dietary Proteins - immunology; fat intake; Feeding. Feeding behavior; Female; Follow-Up Studies; food consumption; food groups; food records; Fruit; Fruit - adverse effects; Fruit - immunology; fruit juices; Fundamental and applied biological sciences. Psychology; HLA-DQ beta-Chains; human resources; Humans; immunology; Infant; Infant Formula; infant formulas; infants; insulin-dependent diabetes mellitus; Insulin-Secreting Cells; Insulin-Secreting Cells - immunology; islets of Langerhans; longitudinal studies; Male; Milk; Milk - adverse effects; Milk - immunology; Odds Ratio; parturition; preschool children; Prospective Studies; risk; sour milk; Vertebrates: anatomy and physiology, studies on body, several organs or systems; IAA; DIPP; GADA; IA-2A; ICA; ZnT8A; Endocrinopathy; Autoimmunity; Human; Immunopathology; HLA-System; Sensitivity; Food intake; Type 1 diabetes; Autoimmune disease; β Cell; Child; Food

Background: Evidence for the role of food consumption during childhood in the development of β cell autoimmunity is scarce and fragmentary. Objective: We set out to study the associations of longitudinal food consumption in children with the development of advanced β cell autoimmunity. Design: Child...