Loss of Tifab , a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor–TRAF6 signaling - Varney, Melinda E.; Niederkorn, Madeline; Konno, Hiroyasu; Matsumura, Takayuki; Gohda, Jin; Yoshida, Nobuaki; Akiyama, Taishin; Christie, Susanne; Fang, Jing; Miller, David; Jerez, Andres; Karsan, Aly; et al. (The Journal of experimental medicine, 2015)
Keywords: Animals; Apoptosis; Bone Marrow Transplantation; Cell Differentiation; Chromosomes, Human, Pair 5; Hematopoiesis; Humans; Male; Mice; Mice, Inbred C57BL; MicroRNAs - physiology; NF-kappa B - antagonists & inhibitors; NF-kappa B - physiology; Proteins - genetics; Proteins - physiology; Signal Transduction - physiology; TNF Receptor-Associated Factor 6 - physiology; Toll-Like Receptors - physiology