The role of primary cilia in myoblast proliferation and cell cycle regulation during myogenesis

• Published in: Cell Structure and Function Vol. 50; no. 1; pp. 53 - 63
• Main Authors: Wu, Zhichao, Chen, Nuo, Takao, Daisuke
• Format: Journal Article
• Language: English
• Published: Japan Japan Society for Cell Biology 01.01.2025; Japan Science and Technology Agency
• Subjects: Animals; Cell Cycle; Cell Differentiation; Cell division; Cell growth; Cell Proliferation; Cell surface; Cilia; Cilia - metabolism; Developmental biology; Growth factors; Homeostasis; Humans; Image processing; imaging; Kinases; Muscle Development; myoblast; Myoblasts; Myoblasts - cytology; Myoblasts - metabolism; Myogenesis; Organelles; proliferation; Proteins; Regenerative medicine; Roles; Signal Transduction; Stem cells; cilia; proliferation; myogenesis; imaging; myoblast

The process of mammalian myogenesis is fundamental to understanding muscle development and holds broad relevance across multiple fields, from developmental biology to regenerative medicine. This review highlights two key aspects: myoblast proliferation and the role of cilia in this process. Myoblast...