Maresin: Macrophage Mediator for Resolving Inflammation and Bridging Tissue Regeneration—A System-Based Preclinical Systematic Review

• Published in: International journal of molecular sciences Vol. 24; no. 13; p. 11012
• Main Authors: Liu, Wen-Chun, Yang, Yu-Hsin, Wang, Yu-Chin, Chang, Wei-Ming, Wang, Chin-Wei
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.07.2023; MDPI
• Subjects: Animals; Anti-Inflammatory Agents; Cardiovascular system; Chronic Disease; Clinical trials; Docosahexaenoic Acids - pharmacology; Docosahexaenoic Acids - therapeutic use; Fatty acids; Health aspects; Humans; Hypotheses; Inflammation; Inflammation - drug therapy; Inflammatory diseases; Kinases; Ligaments; Lipids; Macrophages; Medical research; Medicine, Experimental; Mice; Omega-3 fatty acids; Pain; Pathogens; Peritonitis; Review; Rheumatoid factor; Stem cells; Systematic review; Temporomandibular joint disorders; Tissue engineering; tissue regeneration; maresin; resolving inflammation; preclinical studies; human organ systems

Maresins are lipid mediators derived from omega-3 fatty acids with anti-inflammatory and pro-resolving properties, capable of promoting tissue regeneration and potentially serving as a therapeutic agent for chronic inflammatory diseases. The aim of this review was to systematically investigate precl...