Mesenchymal stem cell immunomodulation: In pursuit of controlling COVID‐19 related cytokine storm

• Published in: Stem cells (Dayton, Ohio) Vol. 39; no. 6; pp. 707 - 722
• Main Authors: Song, Na, Wakimoto, Hiroaki, Rossignoli, Filippo, Bhere, Deepak, Ciccocioppo, Rachele, Chen, Kok‐Siong, Khalsa, Jasneet Kaur, Mastrolia, Ilenia, Samarelli, Anna Valeria, Dominici, Massimo, Shah, Khalid
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.06.2021; Oxford University Press
• Subjects: Alveoli; Cell death; Clinical trials; Concise Review; Concise Reviews; coronavirus; Coronaviruses; COVID-19; Cytokine storm; Cytokines; Edema; Epithelial cells; Epithelium; Fibrosis; Immunomodulation; Inflammation; Intravenous administration; Intravenous infusion; Lung diseases; Lungs; Mesenchymal stem cells; Microenvironments; Normalizing; Pandemics; Public health; Respiratory diseases; Respiratory distress syndrome; SARS‐CoV‐2; Severe acute respiratory syndrome; Severe acute respiratory syndrome coronavirus 2; Stem cells; Thromboembolism; Viral diseases; COVID-19; immunomodulation; coronavirus; SARS-CoV-2; cytokine storm; mesenchymal stem cells

The coronavirus disease 2019 (COVID‐19) pandemic has grown to be a global public health crisis with no safe and effective treatments available yet. Recent findings suggest that severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the coronavirus pathogen that causes COVID‐19, could elicit a...