A disintegrin and metalloprotease 10-containing exosomes derived from nasal polyps promote angiogenesis and vascular permeability

• Published in: Molecular medicine reports Vol. 17; no. 4; pp. 5921 - 5927
• Main Authors: Zhang, Wei, Zhang, Jie, Cheng, Lei, Ni, Haosheng, You, Bo, Shan, Ying, Bao, Lili, Wu, Di, Zhang, Ting, Yue, Huijun, Chen, Jing
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications 01.04.2018; Spandidos Publications UK Ltd; D.A. Spandidos
• Subjects: Analysis; Angiogenesis; Care and treatment; Diagnosis; Disease; Edema; Endothelial cells; Exosomes; Metalloproteinase; Microscopy; Nasal polyps; Particle size; Patients; Permeability; Polyps; Proteinase; Proteins; Signal transduction; Transmission electron microscopes; Umbilical vein; Western blotting; United States > US; Germany

Abnormal angiogenesis and vascular permeability is important for the formation of nasal polyps (NPs). Increasing evidence has indicated that exosomes serve a vital role in modulating angiogenesis and vascular permeability. A disintegrin and metalloprotease 10 (ADAM10), an important type of proteinas...