NONCODEV6: an updated database dedicated to long non-coding RNA annotation in both animals and plants

Abstract NONCODE (http://www.noncode.org/) is a comprehensive database of collection and annotation of noncoding RNAs, especially long non-coding RNAs (lncRNAs) in animals. NONCODEV6 is dedicated to providing the full scope of lncRNAs across plants and animals. The number of lncRNAs in NONCODEV6 has...

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Published inNucleic acids research Vol. 49; no. D1; pp. D165 - D171
Main Authors Zhao, Lianhe, Wang, Jiajia, Li, Yanyan, Song, Tingrui, Wu, Yang, Fang, Shuangsang, Bu, Dechao, Li, Hui, Sun, Liang, Pei, Dong, Zheng, Yu, Huang, Jianqin, Xu, Mingqing, Chen, Runsheng, Zhao, Yi, He, Shunmin
Format Journal Article
LanguageEnglish
Published England Oxford University Press 08.01.2021
Subjects
Animals
Base Sequence
Conserved Sequence
Database Issue
Databases, Nucleic Acid
Exons
Gene Expression Profiling
Humans
Internet
Mice
Molecular Sequence Annotation
Neoplasms - classification
Neoplasms - genetics
Neoplasms - metabolism
Neoplasms - pathology
Plants - genetics
RNA, Long Noncoding - classification
RNA, Long Noncoding - genetics
RNA, Long Noncoding - metabolism
RNA, Messenger - classification
RNA, Messenger - genetics
RNA, Messenger - metabolism
Software
Transcriptome
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Summary:Abstract NONCODE (http://www.noncode.org/) is a comprehensive database of collection and annotation of noncoding RNAs, especially long non-coding RNAs (lncRNAs) in animals. NONCODEV6 is dedicated to providing the full scope of lncRNAs across plants and animals. The number of lncRNAs in NONCODEV6 has increased from 548 640 to 644 510 since the last update in 2017. The number of human lncRNAs has increased from 172 216 to 173 112. The number of mouse lncRNAs increased from 131 697 to 131 974. The number of plant lncRNAs is 94 697. The relationship between lncRNAs in human and cancer were updated with transcriptome sequencing profiles. Three important new features were also introduced in NONCODEV6: (i) updated human lncRNA-disease relationships, especially cancer; (ii) lncRNA annotations with tissue expression profiles and predicted function in five common plants; iii) lncRNAs conservation annotation at transcript level for 23 plant species. NONCODEV6 is accessible through http://www.noncode.org/.
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The authors wish it to be known that, in their opinion, the first three authors should be regarded as Joint First Authors.
ISSN:0305-1048
1362-4962
1362-4962
DOI:10.1093/nar/gkaa1046