microRNA: The Impact on Cancer Stemness and Therapeutic Resistance

• Published in: Cells (Basel, Switzerland) Vol. 9; no. 1; p. 8
• Main Authors: Jiao, Xueqiao, Qian, Xianling, Wu, Longyuan, Li, Bo, Wang, Yi, Kong, Xinyu, Xiong, Lixia
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 18.12.2019; MDPI
• Subjects: Apoptosis; Cancer; Cancer therapies; Cell growth; Chemotherapy; Gene expression; Kinases; Leukemia; Lung cancer; Metastases; Metastasis; MicroRNAs; miRNA; Post-transcription; Prognosis; Radiation therapy; Review; Stem cells; Tumors; cancer therapy; microRNA; cancer; cancer stem cell; therapeutic resistance

Cancer ranks as the second leading cause of death worldwide, causing a large social and economic burden. However, most anti-cancer treatments face the problems of tumor recurrence and metastasis. Therefore, finding an effective cure for cancer needs to be solved urgently. Recently, the discovery of...