Assessing the Protective Role of Epigallocatechin Gallate (EGCG) against Water-Pipe Smoke-Induced Toxicity: A Comparative Study on Gene Expression and Histopathology

• Published in: Molecules (Basel, Switzerland) Vol. 28; no. 22; p. 7502
• Main Authors: Al-Awaida, Wajdy, Goh, Khang Wen, Al-Ameer, Hamzeh J, Gushchina, Yulia Sh, Torshin, Vladimir I, Severin, Alexandr E, Al Bawareed, Omar, Srour, Besan, Al Farraj, Jude, Hamad, Islam
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.11.2023
• Subjects: Analysis; antioxidant genes; Antioxidants; Catechin; Cytokines; Drinking water, Bottled; Enzymes; epigallocatechin gallate (EGCG); Free radicals; Gene expression; Genes; Genetic research; Green tea; Histochemistry; Inflammation; inflammatory markers; Kidneys; Liver; Oxidative stress; Smoking; Tea; Tumor necrosis factor; Water pipes; water-pipe smoke

Exposure to water-pipe smoking, whether flavored or unflavored, has been shown to instigate inflammation and oxidative stress in BALB/c mice. This consequently results in alterations in the expression of inflammatory markers and antioxidant genes. This study aimed to scrutinize the impact of Epigall...