Restoring Migraine Sufferers’ Ability to Function Normally: A Comparison of Rizatriptan and Other Triptans in Randomized Trials

• Published in: European neurology Vol. 48; no. 3; pp. 172 - 177
• Main Authors: Bussone, Gennaro, D’Amico, Domenico, McCarroll, Kathleen A., Gerth, William, Lines, Christopher R.
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland Karger 01.01.2002; S. Karger AG
• Subjects: Administration, Oral; Adolescent; Adult; Aged; Biological and medical sciences; Cardiovascular system; Female; Humans; Indoles - administration & dosage; Male; Medical sciences; Middle Aged; Migraine Disorders - drug therapy; Original Paper; Oxazolidinones - administration & dosage; Pharmacology. Drug treatments; Piperidines - administration & dosage; Randomized Controlled Trials as Topic; Retrospective Studies; Serotonin Receptor Agonists - administration & dosage; Sumatriptan - administration & dosage; Treatment Outcome; Triazoles - administration & dosage; Tryptamines; Vasodilator agents. Cerebral vasodilators; Triptans; Sumatriptan; Zolmitriptan; Migraine; Rizatriptan; 5-HT1B/1D receptor agonists; Naratriptan; Agonist; Prognosis; Tryptamine derivatives; Cardiovascular disease; Serotonine receptor; Serotonin agonist; Functional capacity; Dose activity relation; Vascular disease; Randomization; Pain; Adult; Cerebrovascular disease; Human; Nervous system diseases; Antimigrainous agent; Oral administration; Cerebral disorder; Treatment; Central nervous system disease; Double blind study; Indole derivatives; Comparative study

Background: Many migraine patients are unable to function normally during a migraine attack. Assessments of treatment efficacy have tended to focus on migraine symptoms, rather than looking at functional impact. This study compared the efficacy of different oral triptans for restoring normal functio...