Phycobiliproteins—A Family of Algae-Derived Biliproteins: Productions, Characterization and Pharmaceutical Potentials

Phycobiliproteins (PBPs) are colored and water-soluble biliproteins found in cyanobacteria, rhodophytes, cryptomonads and cyanelles. They are divided into three main types: allophycocyanin, phycocyanin and phycoerythrin, according to their spectral properties. There are two methods for PBPs preparat...

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Published inMarine drugs Vol. 20; no. 7; p. 450
Main Authors Chen, Huaxin, Qi, Hongtao, Xiong, Peng
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 09.07.2022
MDPI
Subjects
Algae
Anticancer properties
Antidiabetics
Antioxidants
Biogenesis
Biosynthesis
Cardiovascular disease
Colour
Cryptophyceae
Cyanelles
Cyanobacteria
Diabetes mellitus
dietary supplements
Endangered & extinct species
fluorescence
fluorescent antibody technique
Fluorescent indicators
Food additives
Food dyes
Functional foods & nutraceuticals
Hosts
Immunofluorescence
Inflammation
pharmaceutical potentials
Pharmaceuticals
Photosynthesis
phycobilin
phycobiliprotein
Phycobiliproteins
Phycocyanin
phycoerythrin
Polypeptides
Radiation
Recombinants
Review
Rhodophyta
Tumors
Water purification
water solubility
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Abstract Phycobiliproteins (PBPs) are colored and water-soluble biliproteins found in cyanobacteria, rhodophytes, cryptomonads and cyanelles. They are divided into three main types: allophycocyanin, phycocyanin and phycoerythrin, according to their spectral properties. There are two methods for PBPs preparation. One is the extraction and purification of native PBPs from Cyanobacteria, Cryptophyta and Rhodophyta, and the other way is the production of recombinant PBPs by heterologous hosts. Apart from their function as light-harvesting antenna in photosynthesis, PBPs can be used as food colorants, nutraceuticals and fluorescent probes in immunofluorescence analysis. An increasing number of reports have revealed their pharmaceutical potentials such as antioxidant, anti-tumor, anti-inflammatory and antidiabetic effects. The advances in PBP biogenesis make it feasible to construct novel PBPs with various activities and produce recombinant PBPs by heterologous hosts at low cost. In this review, we present a critical overview on the productions, characterization and pharmaceutical potentials of PBPs, and discuss the key issues and future perspectives on the exploration of these valuable proteins.
AbstractList Phycobiliproteins (PBPs) are colored and water-soluble biliproteins found in cyanobacteria, rhodophytes, cryptomonads and cyanelles. They are divided into three main types: allophycocyanin, phycocyanin and phycoerythrin, according to their spectral properties. There are two methods for PBPs preparation. One is the extraction and purification of native PBPs from Cyanobacteria, Cryptophyta and Rhodophyta, and the other way is the production of recombinant PBPs by heterologous hosts. Apart from their function as light-harvesting antenna in photosynthesis, PBPs can be used as food colorants, nutraceuticals and fluorescent probes in immunofluorescence analysis. An increasing number of reports have revealed their pharmaceutical potentials such as antioxidant, anti-tumor, anti-inflammatory and antidiabetic effects. The advances in PBP biogenesis make it feasible to construct novel PBPs with various activities and produce recombinant PBPs by heterologous hosts at low cost. In this review, we present a critical overview on the productions, characterization and pharmaceutical potentials of PBPs, and discuss the key issues and future perspectives on the exploration of these valuable proteins.
Phycobiliproteins (PBPs) are colored and water-soluble biliproteins found in cyanobacteria, rhodophytes, cryptomonads and cyanelles. They are divided into three main types: allophycocyanin, phycocyanin and phycoerythrin, according to their spectral properties. There are two methods for PBPs preparation. One is the extraction and purification of native PBPs from Cyanobacteria, Cryptophyta and Rhodophyta, and the other way is the production of recombinant PBPs by heterologous hosts. Apart from their function as light-harvesting antenna in photosynthesis, PBPs can be used as food colorants, nutraceuticals and fluorescent probes in immunofluorescence analysis. An increasing number of reports have revealed their pharmaceutical potentials such as antioxidant, anti-tumor, anti-inflammatory and antidiabetic effects. The advances in PBP biogenesis make it feasible to construct novel PBPs with various activities and produce recombinant PBPs by heterologous hosts at low cost. In this review, we present a critical overview on the productions, characterization and pharmaceutical potentials of PBPs, and discuss the key issues and future perspectives on the exploration of these valuable proteins.Phycobiliproteins (PBPs) are colored and water-soluble biliproteins found in cyanobacteria, rhodophytes, cryptomonads and cyanelles. They are divided into three main types: allophycocyanin, phycocyanin and phycoerythrin, according to their spectral properties. There are two methods for PBPs preparation. One is the extraction and purification of native PBPs from Cyanobacteria, Cryptophyta and Rhodophyta, and the other way is the production of recombinant PBPs by heterologous hosts. Apart from their function as light-harvesting antenna in photosynthesis, PBPs can be used as food colorants, nutraceuticals and fluorescent probes in immunofluorescence analysis. An increasing number of reports have revealed their pharmaceutical potentials such as antioxidant, anti-tumor, anti-inflammatory and antidiabetic effects. The advances in PBP biogenesis make it feasible to construct novel PBPs with various activities and produce recombinant PBPs by heterologous hosts at low cost. In this review, we present a critical overview on the productions, characterization and pharmaceutical potentials of PBPs, and discuss the key issues and future perspectives on the exploration of these valuable proteins.
Author Chen, Huaxin
Xiong, Peng
Qi, Hongtao
AuthorAffiliation 2 School of Life Sciences, Qingdao University, Qingdao 266000, China; qihongtao@qdu.edu.cn
1 School of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China; xiongp@sdut.edu.cn
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  fullname: Xiong, Peng
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Snippet Phycobiliproteins (PBPs) are colored and water-soluble biliproteins found in cyanobacteria, rhodophytes, cryptomonads and cyanelles. They are divided into...
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SubjectTerms Algae
Anticancer properties
Antidiabetics
Antioxidants
Biogenesis
Biosynthesis
Cardiovascular disease
Colour
Cryptophyceae
Cyanelles
Cyanobacteria
Diabetes mellitus
dietary supplements
Endangered & extinct species
fluorescence
fluorescent antibody technique
Fluorescent indicators
Food additives
Food dyes
Functional foods & nutraceuticals
Hosts
Immunofluorescence
Inflammation
pharmaceutical potentials
Pharmaceuticals
Photosynthesis
phycobilin
phycobiliprotein
Phycobiliproteins
Phycocyanin
phycoerythrin
Polypeptides
Radiation
Recombinants
Review
Rhodophyta
Tumors
Water purification
water solubility
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Title Phycobiliproteins—A Family of Algae-Derived Biliproteins: Productions, Characterization and Pharmaceutical Potentials
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Volume 20
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