Pulmonary Infection due to Mycobacterium szulgai

• Published in: Respiration Vol. 70; no. 5; pp. 533 - 536
• Main Authors: Sánchez-Alarcos, José M.F., de Miguel-Díez, Javier, Bonilla, Ignacio, Sicilia, Juan J., Álvarez-Sala, José L.
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland Karger 01.09.2003; S. Karger AG
• Subjects: Aged; Antitubercular Agents - administration & dosage; Bacterial diseases; Biological and medical sciences; Case Report; Drug Therapy, Combination; Human bacterial diseases; Humans; Infectious diseases; Male; Medical sciences; Mycobacterium; Mycobacterium Infections, Nontuberculous - diagnosis; Mycobacterium Infections, Nontuberculous - drug therapy; Mycobacterium szulgai; Nontuberculous Mycobacteria; Pneumology; Tuberculosis and atypical mycobacterial infections; Non-tuberculous mycobacteria; Mycobacterium infections; Antitubercular agent; Mycobacterium szulgai; Agent; Respiratory disease; Mycobacterial infection; Pulmonary infection; Infection; Tuberculosis; Mycobacteriales; Bacteriosis; Mycobacteriaceae; Bacteria; Actinomycetes; Pneumology
• ISSN: 0025-7931; 1423-0356
• DOI: 10.1159/000074214

A 75-year-old man was admitted with cough, purulent sputum, fatigue and weight loss of 10 kg of some months’ duration. His chest radiograph showed poorly defined opacities in the right lung. Eleven years before admission an epidermoid carcinoma of the right lung had been diagnosed and a right bilobar resection had been performed. The patient remained asymptomatic for 8 years. Cultures of 4 consecutive sputum samples were positive for mycobacteria that were identified as Mycobacterium szulgai by gas chromatography. A 6-month regimen of rifampin, isoniazid and pyrazinamide resulted in complete eradication of the mycobacterium. M. szulgai is an unusual pathogen in humans. In the English literature, only 35 cases of pulmonary disease have been reported. Its clinical and radiological characteristics are similar to tuberculosis but in contrast to the rest of the non-tuberculous mycobacteria, M. szulgai has shown in vitro and in vivo susceptibility to most primary antituberculosis drugs.