Objective evaluation of the alleviating effects of Goshajinkigan on peripheral neuropathy induced by paclitaxel/carboplatin therapy: A multicenter collaborative study

• Published in: Experimental and therapeutic medicine Vol. 3; no. 1; pp. 60 - 65
• Main Authors: KAKU, HIROI, KUMAGAI, SEISUKE, ONOUE, HIROKI, TAKADA, ANNA, SHOJI, TADAHIRO, MIURA, FUMIHARU, YOSHIZAKI, AKIRA, SATO, SHINYA, KIGAWA, JUNZO, ARAI, TSUTOMU, TSUNODA, SHINPEI, TOMINAGA, EIICHIRO, AOKI, DAISUKE, SUGIYAMA, TORU
• Format: Journal Article
• Language: English
• Published: Greece D.A. Spandidos 01.01.2012
• Subjects: Goshajinkigan; gynecological cancer; Japanese herbal medicine; kampo drugs; neurotoxicity; paclitaxel; peripheral neuropathy

Paclitaxel/carboplatin chemotherapy for cancer (TC therapy) exhibits neurotoxicity and causes peripheral neuropathy at a high frequency, which is difficult to cope with. In this study, we investigated the efficacy of Goshajinkigan, a traditional Japanese herbal medicine, for TC therapy-induced perip...