Causes and predictors of death in South Africans with systemic lupus erythematosus

• Published in: Rheumatology (Oxford, England) Vol. 46; no. 9; pp. 1487 - 1491
• Main Authors: Wadee, S., Tikly, M., Hopley, M.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.09.2007; Oxford Publishing Limited (England)
• Subjects: Adult; Africa; African Continental Ancestry Group - statistics & numerical data; Biological and medical sciences; Blacks; Bones, joints and connective tissue. Antiinflammatory agents; Cause of Death; Diseases of the osteoarticular system; Female; Humans; Lupus; Lupus Erythematosus, Systemic - complications; Lupus Erythematosus, Systemic - ethnology; Lupus Erythematosus, Systemic - mortality; Lupus Nephritis - ethnology; Lupus Nephritis - mortality; Male; Medical sciences; Middle Aged; Miscellaneous. Osteoarticular involvement in other diseases; Mortality; Opportunistic Infections - complications; Opportunistic Infections - ethnology; Opportunistic Infections - mortality; Pharmacology. Drug treatments; Retrospective Studies; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; South Africa - epidemiology; Survival Analysis; South Africa; Sub-Saharan Africa; Africa; Lupus; Blacks; Mortality; Africa; Kidney disease; Human; Immunopathology; Connective tissue disease; Corticosteroid; Skin disease; Urinary system disease; Prognosis; Diseases of the osteoarticular system; Oral administration; Autoimmune disease; Arthritis; Epidemiology; Survival; Systemic lupus erythematosus; Treatment; Systemic disease; Renal failure; Diagnosis; Predictive factor

Objectives. Little is known about the long-term outcome and mortality patterns in systemic lupus erythematosus (SLE) in sub-Saharan Africa. We undertook a retrospective study of SLE in mainly black, unemployed patients, seen at a tertiary institution in Soweto, South Africa, to determine the causes...