Decreased capillary permeability and capillary density in patients with systemic sclerosis using large-window sodium fluorescein videodensitometry of the ankle

• Published in: Rheumatology (Oxford, England) Vol. 47; no. 9; pp. 1409 - 1412
• Main Authors: Hettema, M. E., Zhang, D., Stienstra, Y., Oomen, P. N. H., Smit, A. J., Kallenberg, C. G. M., Bootsma, H.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.09.2008; Oxford Publishing Limited (England)
• Subjects: Adult; Aged; Ankle - blood supply; Biological and medical sciences; Capillaries - pathology; Capillary Permeability; Densitometry - methods; Diseases of the osteoarticular system; Female; Fluorescein; Humans; Male; Medical sciences; Middle Aged; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; Scleroderma, Systemic - pathology; Scleroderma, Systemic - physiopathology; Skin - blood supply; Sodium fluorescein; Systemic sclerosis; Video Recording - methods; Videodensitometry; Capillary permeability; Videodensitometry; Systemic sclerosis; Sodium fluorescein; Human; Immunopathology; Connective tissue disease; Skin disease; Rheumatology; Autoimmune disease; Permeability; Density; Ankle; Ankle joint; Sodium; Systemic disease; Scleroderma

Objective. Local capillary permeability in patients with SSc has been reported increased when assessed by nail-fold capillaroscopy. We measured capillary permeability at a clinically less affected site by using large-window fluorescein videodensitometry of the ankle. We hypothesized that increased c...