Late radiation-induced heart disease after radiotherapy. Clinical importance, radiobiological mechanisms and strategies of prevention

• Published in: Radiotherapy and oncology Vol. 100; no. 2; pp. 160 - 166
• Main Authors: Andratschke, Nicolaus, Maurer, Jean, Molls, Michael, Trott, Klaus-Rüdiger
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 01.08.2011
• Subjects: Atherosclerosis - etiology; Breast Neoplasms - radiotherapy; Dose-Response Relationship, Radiation; Female; Heart Diseases - etiology; Hematology, Oncology and Palliative Medicine; Humans; Late normal tissue effects; Radiation Injuries - etiology; Radiation Injuries - prevention & control; Radiation-induced heart disease; Radiotherapy - adverse effects; SEER Program; Late normal tissue effects; Radiation-induced heart disease

Abstract The clinical importance of radiation-induced heart disease, in particular in post-operative radiotherapy of breast cancer patients, has been recognised only recently. There is general agreement, that a co-ordinated research effort would be needed to explore all the potential strategies of h...