Conceptual and methodological issues relevant to cytokine and inflammatory marker measurements in clinical research

• Published in: Current opinion in clinical nutrition and metabolic care Vol. 13; no. 5; p. 541
• Main Authors: Zhou, Xin, Fragala, Maren S, McElhaney, Janet E, Kuchel, George A
• Format: Journal Article
• Language: English
• Published: England 01.09.2010
• Subjects: Biological Assay - methods; Biomarkers - blood; Biomedical Research - methods; Cytokines - blood; Enzyme-Linked Immunosorbent Assay - methods; Humans; Inflammation - blood; Inflammation Mediators - blood

To provide clinical investigators with an understanding of factors to consider when wishing to add cytokine and inflammatory marker measurements to their studies. Inflammation involves complex and coordinated responses of the immune system to tissue damage. In the absence of tools to routinely asses...