Amplification of Inflammation by Lubricin Deficiency Implicated in Incident, Erosive Gout Independent of Hyperuricemia - Elsaid, Khaled; Merriman, Tony R.; Rossitto, Leigh‐Ana; Liu‐Bryan, Ru; Karsh, Jacob; Phipps‐Green, Amanda; Jay, Gregory D.; Elsayed, Sandy; Qadri, Marwa; Miner, Marin; Cadzow, Murray; Dambruoso, Talia J.; et al. (Arthritis & rheumatology (Hoboken, N.J.), 2023)
Keywords: Animals; Arthritis; Arthritis, Gouty; Autoimmunitet och inflammation; Autoimmunity and Inflammation; Biomarkers; Blood; Cathepsin G; Cathepsin G - adverse effects; Classification; Criteria; Crystallization; Female; Fibroblasts; Gene sequencing; Genomes; Gout; Gout - genetics; Humans; Hyperuricemia; Inflammasomes; Inflammation; Inflammation - metabolism; Interleukin-1beta - metabolism; Interleukins; Knee; Macrophages; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Proteomics; Rheumatism; Rheumatology; Sequence analysis; Serum proteins; Synovitis; Thrombospondin; Toll-Like Receptor 2 - genetics; Trypsin; Trypsin inhibitors; Uric Acid; Whole genome sequencing; Xanthine Oxidase