Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: Correlation with cognitive performance and neuropathology in mild cognitive impairment and Alzheimer's disease - Ginsberg, Stephen D.; Malek‐Ahmadi, Michael H.; Alldred, Melissa J.; Che, Shaoli; Elarova, Irina; Chen, Yinghua; Jeanneteau, Freddy; Kranz, Thorsten M.; Chao, Moses V; Counts, Scott E.; Mufson, Elliott J. (Hippocampus, 2019)
Keywords: Aged; Aged, 80 and over; Alzheimer Disease - metabolism; Alzheimer Disease - pathology; Alzheimer's disease; brain‐derived neurotrophic factor; CA1 Region, Hippocampal - metabolism; CA1 Region, Hippocampal - pathology; Cognitive ability; Cognitive Dysfunction - metabolism; Cognitive Dysfunction - pathology; Complications; Degeneration; Dementia disorders; Disease Progression; Dissection; DNA microarrays; Female; Gene expression; Glial cell line-derived neurotrophic factor; Hippocampus; Hippocampus - metabolism; Hippocampus - pathology; Humans; Life Sciences; Male; Memory; microarray; Nerve growth factor; Nerve Growth Factors - metabolism; neuritic plaques; Neurodegenerative diseases; Neurofibrillary tangles; Neuropathology; Neurotrophic factors; Pyramidal cells; Pyramidal Cells - metabolism; Pyramidal Cells - pathology; Receptors, Nerve Growth Factor - metabolism; Senile plaques; Short term memory; Spatial memory; Temporal lobe; Trk receptors; TrkA protein; TrkA receptors; TrkB receptors; microarray; brain-derived neurotrophic factor; Trk receptors; neurofibrillary tangles; neuritic plaques