Mitochondrial function and Aβ in Alzheimer's disease postmortem brain

• Published in: Neurobiology of disease Vol. 171; p. 105781
• Main Authors: Troutwine, Benjamin R., Strope, Taylor A., Franczak, Edziu, Lysaker, Colton R., Hamid, Laylan, Mansel, Clayton, Stopperan, Julia A., Gouvion, Cynthia M., Haeri, Mohammad, Swerdlow, Russell H., Wilkins, Heather M.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2022; Elsevier
• Subjects: Alzheimer's disease; Brain; Cytochrome oxidase; Mitochondria; Cytochrome oxidase; Aβ; Brain; Mitochondria; Alzheimer's disease

Mitochondrial dysfunction is observed in Alzheimer's disease (AD). However, the relationship between functional mitochondrial deficits and AD pathologies is not well established in human subjects. Post-mortem human brain tissue from 11 non-demented (ND) and 12 AD subjects was used to examine mi...