Quantification of somatic mutation flow across individual cell division events by lineage sequencing - Brody, Yehuda; Kimmerling, Robert J.; Maruvka, Yosef E.; Benjamin, David; Elacqua, Juniper J.; Haradhvala, Nicholas J.; Kim, Jaegil; Mouw, Kent W.; Frangaj, Kristjana; Koren, Amnon; Getz, Gad; Manalis, Scott R.; et al. (Genome research, 2018)
Keywords: Age; Cell division; Cell Division - genetics; Cell Line; Colon cancer; Deoxyribonucleic acid; DNA; DNA Copy Number Variations; DNA damage; DNA Mutational Analysis - mortality; DNA repair; DNA sequencing; DNA-directed DNA polymerase; Drug resistance; Epithelial cells; Genomes; Genotype; High-Throughput Nucleotide Sequencing - methods; Humans; Method; Mutation; Mutation rates; Phenotypes; Polymorphism, Single Nucleotide; Proofreading; Single-Cell Analysis - methods; Telomerase; Time-Lapse Imaging