Effect of Aerobic Exercise Training and Essential Amino Acid Supplementation for 24 Weeks on Physical Function, Body Composition, and Muscle Metabolism in Healthy, Independent Older Adults: A Randomized Clinical Trial

• Published in: The journals of gerontology. Series A, Biological sciences and medical sciences Vol. 74; no. 10; p. 1598
• Main Authors: Markofski, Melissa M, Jennings, Kristofer, Timmerman, Kyle L, Dickinson, Jared M, Fry, Christopher S, Borack, Michael S, Reidy, Paul T, Deer, Rachel R, Randolph, Amanda, Rasmussen, Blake B, Volpi, Elena
• Format: Journal Article
• Language: English
• Published: United States 01.10.2019
• Subjects: Aged; Amino Acids, Essential - therapeutic use; Body Composition; Dietary Supplements; Double-Blind Method; Exercise; Exercise Tolerance; Female; Humans; Male; Muscle Proteins - metabolism; Muscle Strength; Sarcopenia - metabolism; Sarcopenia - physiopathology; Sarcopenia - prevention & control; Walking Speed; Exercise; Nutrition; Physical performance; Body composition

Essential amino acids (EAA) and aerobic exercise (AE) acutely and independently stimulate skeletal muscle protein anabolism in older adults. In this Phase 1, double-blind, placebo-controlled, randomized clinical trial, we determined if chronic EAA supplementation, AE training, or a combination of th...