TMEM16A, a Homoharringtonine Receptor, as a Potential Endogenic Target for Lung Cancer Treatment - Guo, Shuai; Bai, Xue; Shi, Sai; Deng, Yawen; Kang, Xianjiang; An, Hailong (International journal of molecular sciences, 2021)
Keywords: Animals; Anoctamin-1 - antagonists & inhibitors; Anoctamin-1 - metabolism; Antineoplastic Agents, Phytogenic - chemistry; Antineoplastic Agents, Phytogenic - metabolism; Antineoplastic Agents, Phytogenic - pharmacology; Antineoplastic Agents, Phytogenic - therapeutic use; Apoptosis; Apoptosis - drug effects; Binding Sites; Cancer therapies; Cell growth; Cell Line, Tumor; Cell Movement - drug effects; Cell Proliferation - drug effects; Chemotherapy; Homoharringtonine - chemistry; Homoharringtonine - metabolism; Homoharringtonine - pharmacology; Homoharringtonine - therapeutic use; Humans; Leukemia; Lung cancer; Lung Neoplasms - drug therapy; Lung Neoplasms - metabolism; Lung Neoplasms - pathology; Medical prognosis; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Mutagenesis; Proteins; Radiation therapy; Signal transduction; Software; Transplantation, Heterologous; Wound healing; Beijing China; Grand Island New York; United States--US; China; homoharringtonine; TMEM16A; inhibitor; drug target; lung adenocarcinoma