Clinical Outcomes for Teeth Treated with Electrospun Poly(ε-caprolactone) Fiber Meshes/Mineral Trioxide Aggregate Direct Pulp Capping

• Published in: Journal of endodontics Vol. 41; no. 5; pp. 628 - 636
• Main Authors: Lee, Li-Wan, DDS, MS, Hsiao, Sheng-Huang, MD, PhD, Hung, Wei-Chiang, DDS, Lin, Yun-Ho, DDS, MS, Chen, Po-Yu, MS, Chiang, Chun-Pin, DDS, DMSc
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2015
• Subjects: Adolescent; Adult; Aged; Aluminum Compounds; Biocompatible Materials; Calcium Compounds; Child; Clinical outcome; Dental Pulp Capping - methods; dentin bridge; Dentistry; direct pulp capping; Drug Combinations; Endocrinology & Metabolism; Female; Humans; Male; Materials Testing; Middle Aged; mineral trioxide aggregate; Oxides; poly(ε-caprolactone) fiber meshes; Polyesters; Pulp Capping and Pulpectomy Agents; pulp-exposed permanent teeth; Silicates; Treatment Outcome; Young Adult; dentin bridge; Clinical outcome; direct pulp capping; mineral trioxide aggregate; pulp-exposed permanent teeth; poly(ε-caprolactone) fiber meshes
• ISSN: 0099-2399; 1878-3554
• DOI: 10.1016/j.joen.2015.01.007

Abstract Introduction Mineral trioxide aggregate (MTA) is a biocompatible material for direct pulp capping. This study was designed to compare the clinical outcomes of pulp-exposed teeth treated with either poly(ε-caprolactone) fiber mesh (PCL-FM) as a barrier for MTA (so-called PCL-FM/MTA) or MTA direct pulp capping. Methods Sixty human vital teeth were evenly divided into 4 groups ( n  = 15 in each group). Teeth in groups 1 and 3 had pulp exposure <1 mm in diameter, whereas teeth in groups 2 and 4 had pulp exposure of 1–1.5 mm in diameter. Teeth in groups 1 and 2 were treated with PCL-FM/MTA direct pulp capping, and those in groups 3 and 4 were treated with MTA direct pulp capping. Results Teeth treated with PCL-FM/MTA direct pulp capping needed a significantly shorter mean duration for dentin bridge formation than teeth treated with MTA direct pulp capping. Moreover, teeth with pulp exposure <1.0 mm in diameter needed a significantly shorter mean duration for dentin bridge formation than teeth with pulp exposure of 1–1.5 mm in diameter after either PCL-FM/MTA or MTA direct pulp capping treatment. In addition, teeth treated with PCL-FM/MTA direct pulp capping formed an approximately 3-fold thicker dentin bridge than teeth treated with MTA direct pulp capping 8 weeks or 3 months later. Furthermore, none of the teeth treated with PCL-FM/MTA direct pulp capping showed tooth discoloration after treatment for 3 months. Conclusions PCL-FM/MTA is a better combination material than MTA alone for direct pulp capping of human permanent teeth.