Cocaine-Induced Ventilation/Perfusion Mismatch Mimicking Pulmonary Embolism
Pulmonary complications from cocaine use can range from bronchospasm to vasospasm leading to pulmonary infarction. Profound vasospasm may also lead to perfusion defects presenting as pulmonary embolism on ventilation-perfusion scan. A 65-year-old patient with a past medical history of substance abus...
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Published in | JIM - high impact case reports Vol. 8; p. 2324709620906962 |
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Main Authors | , , |
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SAGE Publications
2020
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Abstract | Pulmonary complications from cocaine use can range from bronchospasm to vasospasm leading to pulmonary infarction. Profound vasospasm may also lead to perfusion defects presenting as pulmonary embolism on ventilation-perfusion scan. A 65-year-old patient with a past medical history of substance abuse and chronic kidney disease presents to the emergency department with sudden-onset chest pain and shortness of breath. Ventilation-perfusion scan revealed filling defect most notably in the lingual lobe. He was later discharged on warfarin for the management of pulmonary embolism. The patient presented to the emergency department 2 weeks later with similar complaints; the international normalized ratio was subtherapeutic, and urine drug screen was positive for cocaine. Repeat ventilation-perfusion scan revealed no filling defects. Follow-up bilateral venous Doppler of lower extremities and D-dimer were within normal limits. |
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AbstractList | Pulmonary complications from cocaine use can range from bronchospasm to vasospasm leading to pulmonary infarction. Profound vasospasm may also lead to perfusion defects presenting as pulmonary embolism on ventilation-perfusion scan. A 65-year-old patient with a past medical history of substance abuse and chronic kidney disease presents to the emergency department with sudden-onset chest pain and shortness of breath. Ventilation-perfusion scan revealed filling defect most notably in the lingual lobe. He was later discharged on warfarin for the management of pulmonary embolism. The patient presented to the emergency department 2 weeks later with similar complaints; the international normalized ratio was subtherapeutic, and urine drug screen was positive for cocaine. Repeat ventilation-perfusion scan revealed no filling defects. Follow-up bilateral venous Doppler of lower extremities and D-dimer were within normal limits. |
Author | Abe, Temidayo Fas, Norberto Surapaneni, Phani Keerthi |
AuthorAffiliation | 1 Morehouse School of Medicine, Atlanta, GA, USA |
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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32054344$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1016/S1054-8807(01)00074-6 10.4103/ijnm.IJNM_60_18 10.15406/jlprr.2017.04.00121 10.2459/JCM.0000000000000511 10.1161/CIRCULATIONAHA.110.940569 10.1165/rcmb.2010-0097OC 10.1097/00003072-200411000-00028 10.1080/10550887.2013.795469 10.1161/ATVBAHA.113.301436 10.1097/00003072-199501000-00016 10.12659/AJCR.894565 10.1016/0002-9343(91)90080-H 10.1001/jama.1990.03440200057023 10.1016/j.ejim.2016.01.009 10.1126/sciadv.aax1532 10.1007/s10067-004-0929-0 10.1093/jat/bky007 10.1161/01.CIR.105.13.1529 10.2484/rcr.v7i3.714 10.1053/j.semnuclmed.2010.07.002 |
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Copyright | 2020 American Federation for Medical Research 2020 American Federation for Medical Research. This work is licensed under the Creative Commons Attribution License https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2020 American Federation for Medical Research 2020 American Federation for Medical Research |
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Keywords | pulmonary embolism cocaine V/Q scan |
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Notes | ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3 Phani Keerthi Surapaneni and Temidayo Abe equally contributed to this case report and are both first authors. |
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Snippet | Pulmonary complications from cocaine use can range from bronchospasm to vasospasm leading to pulmonary infarction. Profound vasospasm may also lead to... |
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StartPage | 2324709620906962 |
SubjectTerms | Case Report Case reports Cocaine Pulmonary embolisms Ventilation |
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Title | Cocaine-Induced Ventilation/Perfusion Mismatch Mimicking Pulmonary Embolism |
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