Deformation-Based Morphometry and Its Relation to Conventional Volumetry of Brain Lateral Ventricles in MRI

• Published in: NeuroImage (Orlando, Fla.) Vol. 13; no. 6; pp. 1140 - 1145
• Main Authors: Gaser, Christian, Nenadic, Igor, Buchsbaum, Bradley R., Hazlett, Erin A., Buchsbaum, Monte S.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2001; Elsevier Limited
• Subjects: Adolescent; Adult; Aged; Automation; Brain; Brain - pathology; Brain mapping; Cerebral Ventricles - pathology; Deformation; Female; Humans; Image Enhancement; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Mathematical Computing; Mental disorders; Middle Aged; Morphology; Morphometry; Neurosciences; Schizophrenia; Schizophrenia - diagnosis; Schizophrenia - pathology; Ventricle; Ventricle (lateral)

Deformation-based morphometry (DBM) is a useful technique to detect morphological differences over the entire brain since it analyses positional differences between every voxel and a standard brain. In this report we compare DBM to semimanual tracing of brain ventricles in a population of 39 patient...