Synthesis, Structure and Stereochemistry of Dispirocompounds Based on Imidazothiazolotriazine and Pyrrolidineoxindole

• Published in: International journal of molecular sciences Vol. 23; no. 22; p. 13820
• Main Authors: Izmest'ev, Alexei N, Karnoukhova, Valentina A, Larin, Alexander A, Kravchenko, Angelina N, Fershtat, Leonid L, Gazieva, Galina A
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 10.11.2022; MDPI
• Subjects: 1,3-dipolar cycloaddition; azomethine ylides; Chromatography; Column chromatography; Cycloaddition; Diastereoisomers; dispirooxindoles; Heterocyclic compounds; Natural products; Nitrogen; oxindolylidene imidazothiazolotriazines; Pyrrolidines - chemistry; rearrangement; Single crystals; Spectrum analysis; Spiro Compounds - chemistry; Stereochemistry; Thiosemicarbazones - chemistry; Triazine; Triazines; azomethine ylides; oxindolylidene imidazothiazolotriazines; dispirooxindoles; rearrangement; 1,3-dipolar cycloaddition

Methods for the synthesis of two types of isomeric dispirocompounds based on imidazothiazolotriazine and pyrrolidineoxindole, differing in the structure of imidazothiazolotriazine fragment, namely, linear dispiro[imidazo[4,5- ]thiazolo[3,2- ][1,2,4]triazine-6,3'-pyrrolidine- 4',3″-indoline...