Baseline Susceptibility of Field Populations of Helicoverpa armigera to Bacillus thuringiensis Vip3Aa Toxin and Lack of Cross-Resistance between Vip3Aa and Cry Toxins
The cotton bollworm Helicoverpa armigera (Hübner) is one of the most damaging cotton pests worldwide. In China, control of this pest has been dependent on transgenic cotton producing a single Bacillus thuringiensis (Bt) protein Cry1Ac since 1997. A small, but significant, increase in H. armigera res...
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| Published in | Toxins Vol. 9; no. 4; p. 127 |
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| Language | English |
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| Abstract | The cotton bollworm Helicoverpa armigera (Hübner) is one of the most damaging cotton pests worldwide. In China, control of this pest has been dependent on transgenic cotton producing a single Bacillus thuringiensis (Bt) protein Cry1Ac since 1997. A small, but significant, increase in H. armigera resistance to Cry1Ac was detected in field populations from Northern China. Since Vip3Aa has a different structure and mode of action than Cry proteins, Bt cotton pyramids containing Vip3Aa are considered as ideal successors of Cry1Ac cotton in China. In this study, baseline susceptibility of H. armigera to Vip3Aa was evaluated in geographic field populations collected in 2014 from major cotton-producing areas of China. The LC50 values of 12 field populations ranged from 0.053 to 1.311 μg/cm2, representing a 25-fold range of natural variation among populations. It is also demonstrated that four laboratory strains of H. armigera with high levels of resistance to Cry1Ac or Cry2Ab have no cross-resistance to Vip3Aa protein. The baseline susceptibility data established here will serve as a comparative reference for detection of field-evolved resistance to Vip3Aa in H. armigera after future deployment of Bt cotton pyramids in China. |
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| AbstractList | The cotton bollworm Helicoverpa armigera (Hübner) is one of the most damaging cotton pests worldwide. In China, control of this pest has been dependent on transgenic cotton producing a single Bacillus thuringiensis (Bt) protein Cry1Ac since 1997. A small, but significant, increase in H. armigera resistance to Cry1Ac was detected in field populations from Northern China. Since Vip3Aa has a different structure and mode of action than Cry proteins, Bt cotton pyramids containing Vip3Aa are considered as ideal successors of Cry1Ac cotton in China. In this study, baseline susceptibility of H. armigera to Vip3Aa was evaluated in geographic field populations collected in 2014 from major cotton-producing areas of China. The LC50 values of 12 field populations ranged from 0.053 to 1.311 μg/cm2, representing a 25-fold range of natural variation among populations. It is also demonstrated that four laboratory strains of H. armigera with high levels of resistance to Cry1Ac or Cry2Ab have no cross-resistance to Vip3Aa protein. The baseline susceptibility data established here will serve as a comparative reference for detection of field-evolved resistance to Vip3Aa in H. armigera after future deployment of Bt cotton pyramids in China. The cotton bollworm Helicoverpa armigera (Hübner) is one of the most damaging cotton pests worldwide. In China, control of this pest has been dependent on transgenic cotton producing a single Bacillus thuringiensis (Bt) protein Cry1Ac since 1997. A small, but significant, increase in H. armigera resistance to Cry1Ac was detected in field populations from Northern China. Since Vip3Aa has a different structure and mode of action than Cry proteins, Bt cotton pyramids containing Vip3Aa are considered as ideal successors of Cry1Ac cotton in China. In this study, baseline susceptibility of H. armigera to Vip3Aa was evaluated in geographic field populations collected in 2014 from major cotton-producing areas of China. The LC 50 values of 12 field populations ranged from 0.053 to 1.311 μg/cm 2 , representing a 25-fold range of natural variation among populations. It is also demonstrated that four laboratory strains of H. armigera with high levels of resistance to Cry1Ac or Cry2Ab have no cross-resistance to Vip3Aa protein. The baseline susceptibility data established here will serve as a comparative reference for detection of field-evolved resistance to Vip3Aa in H. armigera after future deployment of Bt cotton pyramids in China. The cotton bollworm (Hübner) is one of the most damaging cotton pests worldwide. In China, control of this pest has been dependent on transgenic cotton producing a single (Bt) protein Cry1Ac since 1997. A small, but significant, increase in resistance to Cry1Ac was detected in field populations from Northern China. Since Vip3Aa has a different structure and mode of action than Cry proteins, Bt cotton pyramids containing Vip3Aa are considered as ideal successors of Cry1Ac cotton in China. In this study, baseline susceptibility of to Vip3Aa was evaluated in geographic field populations collected in 2014 from major cotton-producing areas of China. The LC values of 12 field populations ranged from 0.053 to 1.311 μg/cm², representing a 25-fold range of natural variation among populations. It is also demonstrated that four laboratory strains of with high levels of resistance to Cry1Ac or Cry2Ab have no cross-resistance to Vip3Aa protein. The baseline susceptibility data established here will serve as a comparative reference for detection of field-evolved resistance to Vip3Aa in after future deployment of Bt cotton pyramids in China. The cotton bollworm Helicoverpa armigera (Hübner) is one of the most damaging cotton pests worldwide. In China, control of this pest has been dependent on transgenic cotton producing a single Bacillus thuringiensis (Bt) protein Cry1Ac since 1997. A small, but significant, increase in H. armigera resistance to Cry1Ac was detected in field populations from Northern China. Since Vip3Aa has a different structure and mode of action than Cry proteins, Bt cotton pyramids containing Vip3Aa are considered as ideal successors of Cry1Ac cotton in China. In this study, baseline susceptibility of H. armigera to Vip3Aa was evaluated in geographic field populations collected in 2014 from major cotton-producing areas of China. The LC50 values of 12 field populations ranged from 0.053 to 1.311 μg/cm², representing a 25-fold range of natural variation among populations. It is also demonstrated that four laboratory strains of H. armigera with high levels of resistance to Cry1Ac or Cry2Ab have no cross-resistance to Vip3Aa protein. The baseline susceptibility data established here will serve as a comparative reference for detection of field-evolved resistance to Vip3Aa in H. armigera after future deployment of Bt cotton pyramids in China.The cotton bollworm Helicoverpa armigera (Hübner) is one of the most damaging cotton pests worldwide. In China, control of this pest has been dependent on transgenic cotton producing a single Bacillus thuringiensis (Bt) protein Cry1Ac since 1997. A small, but significant, increase in H. armigera resistance to Cry1Ac was detected in field populations from Northern China. Since Vip3Aa has a different structure and mode of action than Cry proteins, Bt cotton pyramids containing Vip3Aa are considered as ideal successors of Cry1Ac cotton in China. In this study, baseline susceptibility of H. armigera to Vip3Aa was evaluated in geographic field populations collected in 2014 from major cotton-producing areas of China. The LC50 values of 12 field populations ranged from 0.053 to 1.311 μg/cm², representing a 25-fold range of natural variation among populations. It is also demonstrated that four laboratory strains of H. armigera with high levels of resistance to Cry1Ac or Cry2Ab have no cross-resistance to Vip3Aa protein. The baseline susceptibility data established here will serve as a comparative reference for detection of field-evolved resistance to Vip3Aa in H. armigera after future deployment of Bt cotton pyramids in China. |
| Author | Wu, Shuwen Wu, Yidong Yang, Yihua Wei, Yiyun |
| AuthorAffiliation | College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China; weiyiyun1988@163.com (Y.W.); swwu@njau.edu.cn (S.W.); yhyang@njau.edu.cn (Y.Y.) |
| AuthorAffiliation_xml | – name: College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China; weiyiyun1988@163.com (Y.W.); swwu@njau.edu.cn (S.W.); yhyang@njau.edu.cn (Y.Y.) |
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| Cites_doi | 10.4161/gmcr.20945 10.1017/S0007485308006226 10.1038/nbt.2597 10.1007/978-1-4020-8373-0 10.1016/j.tibtech.2015.12.011 10.1073/pnas.93.11.5389 10.1016/j.cropro.2015.06.006 10.1016/B978-0-12-800197-4.00006-3 10.1073/pnas.94.8.3519 10.1371/journal.pone.0039192 10.1038/nbt907 10.3958/059.035.0321 10.1038/nbt.3100 10.1371/journal.pone.0080134 10.1016/j.cois.2016.04.002 10.1603/EC10105 10.1111/eva.12438 10.1673/031.003.3401 10.1128/MMBR.62.3.775-806.1998 10.1038/nbt.3099 10.1128/MMBR.00060-15 10.1098/rstb.1998.0330 10.1111/eva.12099 10.1128/AEM.69.8.4648-4657.2003 10.1093/jee/100.1.180 10.1371/journal.pone.0022874 |
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| Keywords | Vip3Aa cross-resistance susceptibility Cry1Ac Cry2Ab Helicoverpa armigera |
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| References | Roush (ref_9) 1998; 353 Liu (ref_18) 2017; 10 Bernardi (ref_23) 2015; 76 ref_14 ref_11 Jin (ref_20) 2013; 6 ref_15 Jin (ref_16) 2015; 33 Tabashnik (ref_6) 2013; 31 Estruch (ref_1) 1996; 93 An (ref_17) 2010; 103 Downes (ref_26) 2016; 15 Yang (ref_19) 2009; 99 Crickmore (ref_12) 2015; 33 ref_22 ref_21 Kurtz (ref_24) 2010; 35 Fabrick (ref_7) 2016; 34 Gould (ref_5) 1997; 94 Schnepf (ref_2) 1998; 62 Chakroun (ref_3) 2016; 80 ref_27 Jackson (ref_25) 2007; 100 Storer (ref_8) 2012; 3 Zhao (ref_10) 2003; 21 Payton (ref_28) 2003; 3 ref_4 Lee (ref_13) 2003; 69 18954492 - Bull Entomol Res. 2009 Apr;99(2):175-81 17370826 - J Econ Entomol. 2007 Feb;100(1):180-6 23752438 - Nat Biotechnol. 2013 Jun;31(6):510-21 14608363 - Nat Biotechnol. 2003 Dec;21(12):1493-7 25503384 - Nat Biotechnol. 2015 Feb;33(2):169-74 24478804 - Evol Appl. 2013 Dec;6(8):1222-35 25599179 - Nat Biotechnol. 2015 Feb;33(2):161-8 21309241 - J Econ Entomol. 2010 Dec;103(6):2169-73 9729609 - Microbiol Mol Biol Rev. 1998 Sep;62(3):775-806 26935135 - Microbiol Mol Biol Rev. 2016 Mar 02;80(2):329-50 21857961 - PLoS One. 2011;6(8):e22874 12902253 - Appl Environ Microbiol. 2003 Aug;69(8):4648-57 22761737 - PLoS One. 2012;7(6):e39192 26774592 - Trends Biotechnol. 2016 Apr;34(4):291-302 24260345 - PLoS One. 2013 Nov 18;8(11):e80134 27436735 - Curr Opin Insect Sci. 2016 Jun;15:78-83 22688687 - GM Crops Food. 2012 Jul-Sep;3(3):154-62 8643585 - Proc Natl Acad Sci U S A. 1996 May 28;93(11):5389-94 28127393 - Evol Appl. 2016 Dec 16;10 (2):170-179 11038613 - Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3519-23 15841249 - J Insect Sci. 2003;3:34 |
| References_xml | – volume: 3 start-page: 154 year: 2012 ident: ref_8 article-title: Application of pyramided traits against Lepidoptera in insect resistance management for Bt crops publication-title: GM Crops Food doi: 10.4161/gmcr.20945 – volume: 99 start-page: 175 year: 2009 ident: ref_19 article-title: Introgression of a disrupted cadherin gene enables susceptible Helicoverpa armigera to obtain resistance to Bacillus thuringiensis toxin Cry1Ac publication-title: Bull. Entomol. Res. doi: 10.1017/S0007485308006226 – volume: 31 start-page: 510 year: 2013 ident: ref_6 article-title: Insect resistance to Bt crops: Lessons from the first billion acres publication-title: Nat. Biotechnol. doi: 10.1038/nbt.2597 – ident: ref_11 doi: 10.1007/978-1-4020-8373-0 – volume: 34 start-page: 291 year: 2016 ident: ref_7 article-title: Can pyramids and seed mixtures delay resistance to Bt crops? publication-title: Trends Biotechnol. doi: 10.1016/j.tibtech.2015.12.011 – volume: 93 start-page: 5389 year: 1996 ident: ref_1 article-title: Vip3A, A novel Bacillus thuringiensis vegetative insecticidal protein with a wide spectrum of activities against lepidopteran insects publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.93.11.5389 – volume: 76 start-page: 7 year: 2015 ident: ref_23 article-title: Frequency of resistance to Vip3Aa20 toxin from Bacillus thuringiensis in Spodoptera frugiperda (Lepidoptera: Noctuidae) populations in Brazil publication-title: Crop Prot. doi: 10.1016/j.cropro.2015.06.006 – ident: ref_21 doi: 10.1016/B978-0-12-800197-4.00006-3 – volume: 94 start-page: 3519 year: 1997 ident: ref_5 article-title: Initial frequency of alleles for resistance to Bacillus thuringiensis toxins in field populations of Heliothis virescens publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.94.8.3519 – ident: ref_22 doi: 10.1371/journal.pone.0039192 – volume: 21 start-page: 1493 year: 2003 ident: ref_10 article-title: Transgenic plants expressing two Bacillus thuringiensis toxins delay insect resistance evolution publication-title: Nat. Biotechnol. doi: 10.1038/nbt907 – volume: 35 start-page: 391 year: 2010 ident: ref_24 article-title: A review of Vip3A mode of action and effects on Bt Cry protein-resistant colonies of Lepidopteran larvae publication-title: Southwest Entomol. doi: 10.3958/059.035.0321 – volume: 33 start-page: 169 year: 2015 ident: ref_16 article-title: Large-scale test of the natural refuge strategy for delaying insect resistance to transgenic Bt crops publication-title: Nat. Biotechnol. doi: 10.1038/nbt.3100 – ident: ref_14 doi: 10.1371/journal.pone.0080134 – volume: 15 start-page: 78 year: 2016 ident: ref_26 article-title: Bt resistance in Australian insect pest species publication-title: Curr. Opin. Insect. Sci. doi: 10.1016/j.cois.2016.04.002 – ident: ref_4 – volume: 103 start-page: 2169 year: 2010 ident: ref_17 article-title: Vip3Aa tolerance response of Helicoverpa armigera populations from a Cry1Ac cotton planting region publication-title: J. Econ. Entomol. doi: 10.1603/EC10105 – ident: ref_27 – volume: 10 start-page: 170 year: 2017 ident: ref_18 article-title: Resistance to Bacillus thuringiensis toxin Cry2Ab and survival on single-toxin and pyramided cotton in cotton bollworm from China publication-title: Evol. Appl. doi: 10.1111/eva.12438 – volume: 3 start-page: 34 year: 2003 ident: ref_28 article-title: Overlapping confidence intervals or standard error intervals: What do they mean in terms of statistical significance? publication-title: J. Insect Sci. doi: 10.1673/031.003.3401 – volume: 62 start-page: 775 year: 1998 ident: ref_2 article-title: Bacillus thuringiensis and its pesticidal crystal proteins publication-title: Microbiol. Mol. Biol. Rev. doi: 10.1128/MMBR.62.3.775-806.1998 – volume: 33 start-page: 161 year: 2015 ident: ref_12 article-title: Optimizing pyramided transgenic Bt crops for sustainable pest management publication-title: Nat. Biotechnol. doi: 10.1038/nbt.3099 – volume: 80 start-page: 329 year: 2016 ident: ref_3 article-title: Bacterial vegetative insecticidal proteins (Vip) from entomopathogenic bacteria publication-title: Microbiol. Mol. Biol. Rev. doi: 10.1128/MMBR.00060-15 – volume: 353 start-page: 1777 year: 1998 ident: ref_9 article-title: Two-toxin strategies for management of insecticidal transgenic crops: can pyramiding succeed where pesticide mixtures have not? publication-title: Philos. Trans. R. Soc. Lond. B Biol. Sci. doi: 10.1098/rstb.1998.0330 – volume: 6 start-page: 1222 year: 2013 ident: ref_20 article-title: Dominant resistance to Bt cotton and minor cross-resistance to Bt toxin Cry2Ab in cotton bollworm from China publication-title: Evol. Appl. doi: 10.1111/eva.12099 – volume: 69 start-page: 4648 year: 2003 ident: ref_13 article-title: The mode of action of the Bacillus thuringiensis vegetative insecticidal protein Vip3A differs from that of Cry1Ab delta-endotoxin publication-title: Appl. Environ. Microbiol. doi: 10.1128/AEM.69.8.4648-4657.2003 – volume: 100 start-page: 180 year: 2007 ident: ref_25 article-title: Cross-resistance responses of Cry1Ac-selected Heliothis virescens (Lepidoptera: Noctuidae) to the Bacillus thuringiensis protein Vip3A publication-title: J. Econ. Entomol. doi: 10.1093/jee/100.1.180 – ident: ref_15 doi: 10.1371/journal.pone.0022874 – reference: 25503384 - Nat Biotechnol. 2015 Feb;33(2):169-74 – reference: 15841249 - J Insect Sci. 2003;3:34 – reference: 21857961 - PLoS One. 2011;6(8):e22874 – reference: 22688687 - GM Crops Food. 2012 Jul-Sep;3(3):154-62 – reference: 26774592 - Trends Biotechnol. 2016 Apr;34(4):291-302 – reference: 12902253 - Appl Environ Microbiol. 2003 Aug;69(8):4648-57 – reference: 25599179 - Nat Biotechnol. 2015 Feb;33(2):161-8 – reference: 27436735 - Curr Opin Insect Sci. 2016 Jun;15:78-83 – reference: 17370826 - J Econ Entomol. 2007 Feb;100(1):180-6 – reference: 11038613 - Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3519-23 – reference: 24478804 - Evol Appl. 2013 Dec;6(8):1222-35 – reference: 22761737 - PLoS One. 2012;7(6):e39192 – reference: 24260345 - PLoS One. 2013 Nov 18;8(11):e80134 – reference: 9729609 - Microbiol Mol Biol Rev. 1998 Sep;62(3):775-806 – reference: 21309241 - J Econ Entomol. 2010 Dec;103(6):2169-73 – reference: 14608363 - Nat Biotechnol. 2003 Dec;21(12):1493-7 – reference: 18954492 - Bull Entomol Res. 2009 Apr;99(2):175-81 – reference: 28127393 - Evol Appl. 2016 Dec 16;10 (2):170-179 – reference: 8643585 - Proc Natl Acad Sci U S A. 1996 May 28;93(11):5389-94 – reference: 23752438 - Nat Biotechnol. 2013 Jun;31(6):510-21 – reference: 26935135 - Microbiol Mol Biol Rev. 2016 Mar 02;80(2):329-50 |
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| Snippet | The cotton bollworm Helicoverpa armigera (Hübner) is one of the most damaging cotton pests worldwide. In China, control of this pest has been dependent on... The cotton bollworm (Hübner) is one of the most damaging cotton pests worldwide. In China, control of this pest has been dependent on transgenic cotton... The cotton bollworm Helicoverpa armigera (Hübner) is one of the most damaging cotton pests worldwide. In China, control of this pest has been dependent on... |
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| SubjectTerms | Animals Bacterial Proteins - toxicity Cotton Cross-resistance Cry1Ac Cry1Ac toxin Cry2Ab Damage Endotoxins - toxicity Helicoverpa armigera Hemolysin Proteins - toxicity Larva - drug effects Lethal Dose 50 Mode of action Moths - drug effects Pest control Pests Populations Proteins Pyramids susceptibility Toxins Vip3Aa |
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| Title | Baseline Susceptibility of Field Populations of Helicoverpa armigera to Bacillus thuringiensis Vip3Aa Toxin and Lack of Cross-Resistance between Vip3Aa and Cry Toxins |
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