Linearity and non-linearity in cerebral hemodynamics

• Published in: Medical engineering & physics Vol. 25; no. 8; pp. 633 - 646
• Main Authors: Giller, Cole A., Mueller, Martin
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.10.2003
• Subjects: Blood Flow Velocity; Blood Pressure; Brain - blood supply; Brain - physiology; Cerebral hemodynamics; Cerebrovascular Circulation - physiology; Computer Simulation; Echoencephalography - methods; Hemodynamics - physiology; Humans; Linear Models; Male; Middle Cerebral Artery - diagnostic imaging; Middle Cerebral Artery - physiology; Models, Cardiovascular; Models, Neurological; Nonlinear Dynamics; Nonlinearity; Reproducibility of Results; Sensitivity and Specificity; Stochastic Processes; System identification; Transcranial Doppler ultrasound; Transcranial Doppler ultrasound; Nonlinearity; System identification; Cerebral hemodynamics

Background: Transcranial Doppler ultrasound has been extensively used to study cerebral hemodynamics, and yet the basic characteristics of the input/output system of blood pressure/velocity are little known. We examine whether this system can best be considered linear or non-linear. Methods: We asse...