In vitro and in vivo Virulence Potential of the Emergent Species of the Acinetobacter baumannii (Ab) Group

The increased use of molecular identification methods and mass spectrometry has revealed that Acinetobacter spp. of the A. baumannii (Ab) group other than A. baumannii are increasingly being recovered from human samples and may pose a health challenge if neglected. In this study 76 isolates of 5 spe...

Full description

Saved in:
Bibliographic Details
Published inFrontiers in microbiology Vol. 10; p. 2429
Main Authors Cosgaya, Clara, Ratia, Carlos, Marí-Almirall, Marta, Rubio, Laia, Higgins, Paul G., Seifert, Harald, Roca, Ignasi, Vila, Jordi
Format Journal Article
LanguageEnglish
Published Frontiers Media 24.10.2019
Frontiers Media S.A
Subjects
Acinetobacter
Bacteris gramnegatius
biofilm formation
C. elegans
Drug resistance
efflux pumps
Gram-negative bacteria
Microbiology
multi-drug resistance
Resistència als medicaments
virulence
Online AccessGet full text

Cover

Abstract The increased use of molecular identification methods and mass spectrometry has revealed that Acinetobacter spp. of the A. baumannii (Ab) group other than A. baumannii are increasingly being recovered from human samples and may pose a health challenge if neglected. In this study 76 isolates of 5 species within the Ab group (A. baumannii n = 16, A. lactucae n = 12, A. nosocomialis n = 16, A. pittii n = 20, and A. seifertii n = 12), were compared in terms of antimicrobial susceptibility, carriage of intrinsic resistance genes, biofilm formation, and the ability to kill Caenorhabditis elegans in an infection assay. In agreement with previous studies, antimicrobial resistance was common among A. baumannii while all other species were generally more susceptible. Carriage of genes encoding different efflux pumps was frequent in all species and the presence of intrinsic class D β-lactamases was reported in A. baumannii, A. lactucae (heterotypic synonym of A. dijkshoorniae) and A. pittii but not in A. nosocomialis and A. seifertii. A. baumannii and A. nosocomialis presented weaker pathogenicity in our in vitro and in vivo models than A. seifertii, A. pittii and, especially, A. lactucae. Isolates from the former species showed decreased biofilm formation and required a longer time to kill C. elegans nematodes. These results suggest relevant differences in terms of antibiotic susceptibility patterns among the members of the Ab group as well as highlight a higher pathogenicity potential for the emerging species of the group in this particular model. Nevertheless, the impact of such potential in the human host still remains to be determined.
AbstractList The increased use of molecular identification methods and mass spectrometry has revealed that Acinetobacter spp. of the A. baumannii (Ab) group other than A. baumannii are increasingly being recovered from human samples and may pose a health challenge if neglected. In this study 76 isolates of 5 species within the Ab group (A. baumannii n = 16, A. lactucae n = 12, A. nosocomialis n = 16, A. pittii n = 20, and A. seifertii n = 12), were compared in terms of antimicrobial susceptibility, carriage of intrinsic resistance genes, biofilm formation, and the ability to kill Caenorhabditis elegans in an infection assay. In agreement with previous studies, antimicrobial resistance was common among A. baumannii while all other species were generally more susceptible. Carriage of genes encoding different efflux pumps was frequent in all species and the presence of intrinsic class D β-lactamases was reported in A. baumannii, A. lactucae (heterotypic synonym of A. dijkshoorniae) and A. pittii but not in A. nosocomialis and A. seifertii. A. baumannii and A. nosocomialis presented weaker pathogenicity in our in vitro and in vivo models than A. seifertii, A. pittii and, especially, A. lactucae. Isolates from the former species showed decreased biofilm formation and required a longer time to kill C. elegans nematodes. These results suggest relevant differences in terms of antibiotic susceptibility patterns among the members of the Ab group as well as highlight a higher pathogenicity potential for the emerging species of the group in this particular model. Nevertheless, the impact of such potential in the human host still remains to be determined.
The increased use of molecular identification methods and mass spectrometry has revealed that Acinetobacter spp. of the A. baumannii (Ab) group other than A. baumannii are increasingly being recovered from human samples and may pose a health challenge if neglected. In this study 76 isolates of 5 species within the Ab group ( A. baumannii n = 16, A. lactucae n = 12, A. nosocomialis n = 16, A. pittii n = 20, and A. seifertii n = 12), were compared in terms of antimicrobial susceptibility, carriage of intrinsic resistance genes, biofilm formation, and the ability to kill Caenorhabditis elegans in an infection assay. In agreement with previous studies, antimicrobial resistance was common among A. baumannii while all other species were generally more susceptible. Carriage of genes encoding different efflux pumps was frequent in all species and the presence of intrinsic class D β-lactamases was reported in A. baumannii , A. lactucae (heterotypic synonym of A. dijkshoorniae ) and A. pittii but not in A. nosocomialis and A. seifertii . A. baumannii and A. nosocomialis presented weaker pathogenicity in our in vitro and in vivo models than A. seifertii , A. pittii and, especially, A. lactucae . Isolates from the former species showed decreased biofilm formation and required a longer time to kill C. elegans nematodes. These results suggest relevant differences in terms of antibiotic susceptibility patterns among the members of the Ab group as well as highlight a higher pathogenicity potential for the emerging species of the group in this particular model. Nevertheless, the impact of such potential in the human host still remains to be determined.
Author Cosgaya, Clara
Seifert, Harald
Higgins, Paul G.
Roca, Ignasi
Rubio, Laia
Marí-Almirall, Marta
Vila, Jordi
Ratia, Carlos
AuthorAffiliation 1 ISGlobal, Hospital Clínic – University of Barcelona , Barcelona , Spain
3 German Center for Infection Research (DZIF) , Bonn , Germany
2 Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne , Cologne , Germany
AuthorAffiliation_xml – name: 2 Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne , Cologne , Germany
– name: 1 ISGlobal, Hospital Clínic – University of Barcelona , Barcelona , Spain
– name: 3 German Center for Infection Research (DZIF) , Bonn , Germany
Author_xml – sequence: 1
  givenname: Clara
  surname: Cosgaya
  fullname: Cosgaya, Clara
– sequence: 2
  givenname: Carlos
  surname: Ratia
  fullname: Ratia, Carlos
– sequence: 3
  givenname: Marta
  surname: Marí-Almirall
  fullname: Marí-Almirall, Marta
– sequence: 4
  givenname: Laia
  surname: Rubio
  fullname: Rubio, Laia
– sequence: 5
  givenname: Paul G.
  surname: Higgins
  fullname: Higgins, Paul G.
– sequence: 6
  givenname: Harald
  surname: Seifert
  fullname: Seifert, Harald
– sequence: 7
  givenname: Ignasi
  surname: Roca
  fullname: Roca, Ignasi
– sequence: 8
  givenname: Jordi
  surname: Vila
  fullname: Vila, Jordi
BookMark eNpVkttrHCEUxoeS0qRp3vvoY_qwG2_jOC-FJaTpQqCFXuibqHPcuMzoVp2F_Ped2d2ERvByvuP5qfi9r85CDFBVHwleMibbGzd4a5YUk3aJKaftm-qCCMEXDNM_Z_-tz6urnLd4ahzTaXxXnTPSYNlifFFt1wHtfUkR6dAhPwf7iH77NPYQLKDvsUAoXvcoOlQeAd0NkDaThH7swHrIz_rK-gAlGm0LJGT0OOgQvEfXK_MJ3ac47j5Ub53uM1yd5svq15e7n7dfFw_f7te3q4eF5ZKURe0YEAnMOadNC7LRlBmOp6TgpJatqLFsnCGECiCGU-s6yXhTE9yCNaZhl9X6yO2i3qpd8oNOTypqrw5CTBulU_G2B-VEJwThDTeW81Y742otWyukM5pDIyfW5yNrN5oBOjs9POn-FfR1JvhHtYl7JSQlQrIJQI4Am0erElhIVpdD4Uswd4obqtj0ZTWeaq5Ph6b4d4Rc1OCzhb7XAeKYFWWEiZoIMm_FJ3yKOSdwL1cjWM0uUQeXqNkl6uAS9g9PxrGE
CitedBy_id crossref_primary_10_3389_fmicb_2024_1351161
crossref_primary_10_3390_pathogens11080838
crossref_primary_10_3390_microorganisms9040743
crossref_primary_10_1128_JCM_01309_20
crossref_primary_10_3389_fcimb_2022_943735
crossref_primary_10_3389_fcimb_2021_739211
crossref_primary_10_1016_j_bjid_2023_103687
crossref_primary_10_3390_microorganisms9020242
crossref_primary_10_3389_fmicb_2021_676510
crossref_primary_10_1093_jac_dkaa432
crossref_primary_10_1089_phage_2021_0014
crossref_primary_10_3389_fmicb_2023_1264030
crossref_primary_10_1093_jac_dkae024
crossref_primary_10_3390_ijms25042333
crossref_primary_10_1128_MRA_00220_23
crossref_primary_10_34172_jlms_2020_31
Cites_doi 10.1099/jmm.0.000069
10.1186/s12879-017-2589-0
10.1099/ijs.0.000043
10.1093/nar/gkh340
10.1128/aac.00622-11
10.1099/mic.0.026054-0
10.1093/jac/dkr200
10.1128/aac.01360-17
10.1016/j.cmi.2016.11.020
10.1128/jcm.01765-10
10.1097/ccm.0000000000000125
10.1089/mdr.2018.0182
10.1128/cmr.00058-07
10.1016/j.ijantimicag.2008.06.027
10.1371/journal.pone.0191748
10.1111/j.1469-0691.2007.01916.x
10.1093/jac/dkx322
10.1371/journal.pone.0046984
10.1017/s0950268817002849
10.1179/1973947812y.0000000052
10.1128/aac.01957-15
10.1016/j.jinf.2014.09.004
10.1111/apm.12455
10.1128/jcm.01818-15
10.1128/jcm.01194-12
10.3389/fmicb.2012.00148
10.1186/s12879-016-1678-9
10.1016/j.diagmicrobio.2013.03.020
10.1093/jac/dkp428
10.1093/jac/dkq521
10.1128/aac.01514-17
10.1371/journal.pone.0010034
10.1016/j.jhin.2018.03.019
10.1128/aac.01261-13
10.2217/fmb.11.30
10.1016/j.jinf.2011.12.008
10.1111/j.1574-695X.2008.00403.x
10.1093/jac/dkt065
10.1371/journal.pone.0010732
10.1186/1471-2334-13-282
10.1111/1469-0691.12026
10.1074/jbc.M117.808394
10.1093/cid/ciq154
10.1093/jac/dkp427
10.3390/pathogens3030704
10.1016/j.ijmm.2012.03.003
10.1099/jmm.0.46433-0
10.1128/aac.01455-15
10.1093/jac/dkm231
10.1007/s12275-012-1555-1
10.1128/jcm.43.9.4328-4335.2005
10.3389/fmicb.2016.00049
10.1093/molbev/mst197
10.1099/ijsem.0.001318
10.1128/aac.02992-14
10.2436/20.1501.01.161
10.1016/j.ijantimicag.2011.08.006
10.1111/j.1469-0691.2012.03988.x
10.1111/j.1469-0691.2011.03570.x
10.4014/jmb.1507.07076
10.1128/JCM.33.1.11-15.1995
10.1159/000335599
10.1038/nrmicro.2017.148
ContentType Journal Article
Copyright cc by (c) Cosgaya et al., 2019 info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/3.0/es
Copyright © 2019 Cosgaya, Ratia, Marí-Almirall, Rubio, Higgins, Seifert, Roca and Vila. 2019 Cosgaya, Ratia, Marí-Almirall, Rubio, Higgins, Seifert, Roca and Vila
Copyright_xml – notice: cc by (c) Cosgaya et al., 2019 info:eu-repo/semantics/openAccess <a href="http://creativecommons.org/licenses/by/3.0/es/">http://creativecommons.org/licenses/by/3.0/es/</a>
– notice: Copyright © 2019 Cosgaya, Ratia, Marí-Almirall, Rubio, Higgins, Seifert, Roca and Vila. 2019 Cosgaya, Ratia, Marí-Almirall, Rubio, Higgins, Seifert, Roca and Vila
DBID AAYXX
CITATION
7X8
XX2
5PM
DOA
DOI 10.3389/fmicb.2019.02429
DatabaseName CrossRef
MEDLINE - Academic
Recercat
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
MEDLINE - Academic
DatabaseTitleList


Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
DeliveryMethod fulltext_linktorsrc
Discipline Biology
EISSN 1664-302X
EndPage 2429
ExternalDocumentID oai_doaj_org_article_f6d661474bc449afbf5a89c68fba4e78
oai_recercat_cat_2072_366450
10_3389_fmicb_2019_02429
GrantInformation_xml – fundername: Departament de Salut, Generalitat de Catalunya
  grantid: SLT002/16/00349
– fundername: Ministerio de Educación, Cultura y Deporte
  grantid: FPU 13/02564; FPU 14/06357
– fundername: Instituto de Salud Carlos III
  grantid: REIPI RD16/0016/0010; PI17/01932; PI17/01468
– fundername: Departament d'Universitats, Recerca i Societat de la Informació
GroupedDBID 53G
5VS
9T4
AAFWJ
AAKDD
AAYXX
ACGFO
ACGFS
ACXDI
ADBBV
ADRAZ
AENEX
AFPKN
ALMA_UNASSIGNED_HOLDINGS
AOIJS
BAWUL
BCNDV
CITATION
DIK
ECGQY
GROUPED_DOAJ
GX1
HYE
IAO
IEA
IHR
KQ8
M48
M~E
O5R
O5S
OK1
PGMZT
RNS
RPM
7X8
ITC
XX2
5PM
ID FETCH-LOGICAL-c481t-5f3e18e3fffab9e87a23b40c4864158965087fb1126e1b42cfd83475109ecbb73
IEDL.DBID RPM
ISSN 1664-302X
IngestDate Sun Sep 29 07:13:05 EDT 2024
Tue Sep 17 21:19:51 EDT 2024
Fri Sep 27 12:10:26 EDT 2024
Fri Aug 16 02:03:40 EDT 2024
Thu Sep 26 16:17:58 EDT 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Language English
License This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c481t-5f3e18e3fffab9e87a23b40c4864158965087fb1126e1b42cfd83475109ecbb73
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Edited by: Paolo Visca, Roma Tre University, Italy
Reviewed by: Raffaele Zarrilli, University of Naples Federico II, Italy; Wangxue Chen, National Research Council Canada (NRC-CNRC), Canada; Phil Rather, Emory University, United States
This article was submitted to Antimicrobials, Resistance and Chemotherapy, a section of the journal Frontiers in Microbiology
OpenAccessLink https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821683/
PMID 31708900
PQID 2313651610
PQPubID 23479
PageCount 1
ParticipantIDs doaj_primary_oai_doaj_org_article_f6d661474bc449afbf5a89c68fba4e78
pubmedcentral_primary_oai_pubmedcentral_nih_gov_6821683
csuc_recercat_oai_recercat_cat_2072_366450
proquest_miscellaneous_2313651610
crossref_primary_10_3389_fmicb_2019_02429
PublicationCentury 2000
PublicationDate 2019-10-24
PublicationDateYYYYMMDD 2019-10-24
PublicationDate_xml – month: 10
  year: 2019
  text: 2019-10-24
  day: 24
PublicationDecade 2010
PublicationTitle Frontiers in microbiology
PublicationYear 2019
Publisher Frontiers Media
Frontiers Media S.A
Publisher_xml – name: Frontiers Media
– name: Frontiers Media S.A
References Kaliterna (B27) 2013; 25
Magiorakos (B37) 2012; 18
Wisplinghoff (B62) 2012; 64
McQueary (B39) 2012; 50
Fitzpatrick (B17) 2015; 70
Bogaerts (B3) 2013; 68
Nemec (B43) 2015; 65
Nowak (B46) 2017; 72
Lee (B34) 2012; 56
Gentile (B19) 2014; 3
Diancourt (B12) 2010; 5
Larcher (B31) 2017; 17
Roca (B53) 2012; 3
Schleicher (B56) 2013; 19
Peleg (B50) 2008; 21
Lee (B35) 2013; 19
Pailhories (B47) 2018; 99
Vaneechoutte (B60) 1995; 33
Mari-Almirall (B38) 2017; 23
Higgins (B23); 65
Chusri (B8) 2014; 58
de Breij (B10) 2010; 5
Fitzpatrick (B18) 2016; 54
Chen (B5) 2018; 13
Seifert (B57) 2005; 43
Skiebe (B58) 2012; 302
Jain (B26) 2016; 16
Gundi (B21) 2009; 155
Edgar (B13) 2004; 32
Cayo (B4) 2016; 60
Nemec (B44) 2007; 60
Rodriguez-Baño (B55) 2008; 14
Lee (B32) 2014; 42
Cosgaya (B9) 2016
Espinal (B16) 2011; 6
Chuang (B7) 2011; 52
Lin (B36) 2009; 33
Peleg (B49) 2012; 7
Rocha (B54) 2018; 146
Perichon (B51) 2014; 58
De Silva (B11) 2018; 62
Kinsella (B29) 2017; 292
Rajamohan (B52) 2010; 65
Hou (B25) 2012; 58
Park (B48) 2012; 39
Na (B41) 2016; 26
Espinal (B15) 2019; 25
Tamura (B59) 2013; 30
Chu (B6) 2006; 55
Bitrian (B2) 2012; 15
Higgins (B24); 48
Modarresi (B40) 2015; 123
Lai (B30) 2012; 50
Nowak (B45) 2015; 64
Karah (B28) 2011; 66
Narciso (B42) 2017; 61
Al Atrouni (B1) 2016; 7
Wang (B61) 2013; 76
Giannouli (B20) 2013; 13
Harding (B22) 2018; 16
Lee (B33) 2011; 66
Wroblewska (B63) 2008; 53
Espinal (B14) 2015; 59
References_xml – volume: 64
  start-page: 630
  year: 2015
  ident: B45
  article-title: Prevalence of eight resistance-nodulation-division efflux pump genes in epidemiologically characterized Acinetobacter baumannii of worldwide origin.
  publication-title: J. Med. Microbiol.
  doi: 10.1099/jmm.0.000069
  contributor:
    fullname: Nowak
– volume: 17
  year: 2017
  ident: B31
  article-title: First report of cavitary pneumonia due to community-acquired Acinetobacter pittii, study of virulence and overview of pathogenesis and treatment.
  publication-title: BMC Infect. Dis.
  doi: 10.1186/s12879-017-2589-0
  contributor:
    fullname: Larcher
– volume: 65
  start-page: 934
  year: 2015
  ident: B43
  article-title: Acinetobacter seifertii sp. nov., a member of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex isolated from human clinical specimens.
  publication-title: Int. J. Syst. Evol. Microbiol.
  doi: 10.1099/ijs.0.000043
  contributor:
    fullname: Nemec
– volume: 32
  start-page: 1792
  year: 2004
  ident: B13
  article-title: MUSCLE: multiple sequence alignment with high accuracy and high throughput.
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkh340
  contributor:
    fullname: Edgar
– volume: 56
  start-page: 1124
  year: 2012
  ident: B34
  article-title: Emergence of carbapenem-resistant non-baumannii species of Acinetobacter harboring a blaOXA–51-like gene that is intrinsic to A. baumannii.
  publication-title: Antimicrob. Agents Chemother.
  doi: 10.1128/aac.00622-11
  contributor:
    fullname: Lee
– volume: 155
  start-page: 2333
  year: 2009
  ident: B21
  article-title: Validation of partial rpoB gene sequence analysis for the identification of clinically important and emerging Acinetobacter species.
  publication-title: Microbiology
  doi: 10.1099/mic.0.026054-0
  contributor:
    fullname: Gundi
– volume: 66
  start-page: 1839
  year: 2011
  ident: B33
  article-title: Acinetobacter baumannii and Acinetobacter genospecies 13TU and 3 bacteraemia: comparison of clinical features, prognostic factors and outcomes.
  publication-title: J. Antimicrob. Chemother.
  doi: 10.1093/jac/dkr200
  contributor:
    fullname: Lee
– volume: 61
  year: 2017
  ident: B42
  article-title: Detection of OXA-58-producing Acinetobacter seifertii recovered from a black-necked Swan at a Zoo Lake.
  publication-title: Antimicrob. Agents Chemother.
  doi: 10.1128/aac.01360-17
  contributor:
    fullname: Narciso
– volume: 23
  start-page: 210.e1
  year: 2017
  ident: B38
  article-title: MALDI-TOF/MS identification of species from the Acinetobacter baumannii (Ab) group revisited: inclusion of the novel A. seifertii and A. dijkshoorniae species.
  publication-title: Clin. Microbiol. Infect.
  doi: 10.1016/j.cmi.2016.11.020
  contributor:
    fullname: Mari-Almirall
– volume: 48
  start-page: 4592
  ident: B24
  article-title: gyrB multiplex PCR to differentiate between Acinetobacter calcoaceticus and Acinetobacter genomic species 3.
  publication-title: J. Clin. Microbiol.
  doi: 10.1128/jcm.01765-10
  contributor:
    fullname: Higgins
– volume: 42
  start-page: 1081
  year: 2014
  ident: B32
  article-title: Risk factors and outcome analysis of Acinetobacter baumannii complex bacteremia in critical patients.
  publication-title: Crit. Care Med.
  doi: 10.1097/ccm.0000000000000125
  contributor:
    fullname: Lee
– volume: 25
  start-page: 752
  year: 2019
  ident: B15
  article-title: Relationship between different resistance mechanisms and virulence in Acinetobacter baumannii.
  publication-title: Microb. Drug Resist.
  doi: 10.1089/mdr.2018.0182
  contributor:
    fullname: Espinal
– volume: 21
  start-page: 538
  year: 2008
  ident: B50
  article-title: Acinetobacter baumannii: emergence of a successful pathogen.
  publication-title: Clin. Microbiol. Rev.
  doi: 10.1128/cmr.00058-07
  contributor:
    fullname: Peleg
– volume: 33
  start-page: 27
  year: 2009
  ident: B36
  article-title: Distribution of the multidrug efflux pump genes, adeABC, adeDE and adeIJK, and class 1 integron genes in multiple-antimicrobial-resistant clinical isolates of Acinetobacter baumannii-Acinetobacter calcoaceticus complex.
  publication-title: Int. J. Antimicrob. Agents
  doi: 10.1016/j.ijantimicag.2008.06.027
  contributor:
    fullname: Lin
– volume: 13
  year: 2018
  ident: B5
  article-title: Comparison of clinical manifestations and antibiotic resistances among three genospecies of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex.
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0191748
  contributor:
    fullname: Chen
– volume: 14
  start-page: 276
  year: 2008
  ident: B55
  article-title: Biofilm formation in Acinetobacter baumannii: associated features and clinical implications.
  publication-title: Clin. Microbiol. Infect.
  doi: 10.1111/j.1469-0691.2007.01916.x
  contributor:
    fullname: Rodriguez-Baño
– volume: 72
  start-page: 3277
  year: 2017
  ident: B46
  article-title: High incidence of pandrug-resistant Acinetobacter baumannii isolates collected from patients with ventilator-associated pneumonia in Greece, Italy and Spain as part of the MagicBullet clinical trial.
  publication-title: J. Antimicrob. Chemother.
  doi: 10.1093/jac/dkx322
  contributor:
    fullname: Nowak
– volume: 7
  year: 2012
  ident: B49
  article-title: The success of Acinetobacter species; genetic, metabolic and virulence attributes.
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0046984
  contributor:
    fullname: Peleg
– volume: 146
  start-page: 524
  year: 2018
  ident: B54
  article-title: Species distribution, sequence types and antimicrobial resistance of Acinetobacter spp. from cystic fibrosis patients.
  publication-title: Epidemiol. Infect.
  doi: 10.1017/s0950268817002849
  contributor:
    fullname: Rocha
– volume: 25
  start-page: 60
  year: 2013
  ident: B27
  article-title: The ability of biofilm formation in clinical isolates of Acinetobacter baumannii belonging to two different European clones causing outbreaks in the Split University Hospital, Croatia.
  publication-title: J. Chemother.
  doi: 10.1179/1973947812y.0000000052
  contributor:
    fullname: Kaliterna
– volume: 60
  start-page: 2589
  year: 2016
  ident: B4
  article-title: Old clinical isolates of Acinetobacter seifertii in Brazil producing OXA-58.
  publication-title: Antimicrob. Agents Chemother.
  doi: 10.1128/aac.01957-15
  contributor:
    fullname: Cayo
– volume: 70
  start-page: 144
  year: 2015
  ident: B17
  article-title: Influence of ACB complex genospecies on clinical outcomes in a U.S. hospital with high rates of multidrug resistance.
  publication-title: J. Infect.
  doi: 10.1016/j.jinf.2014.09.004
  contributor:
    fullname: Fitzpatrick
– volume: 123
  start-page: 959
  year: 2015
  ident: B40
  article-title: Effect of iron on expression of efflux pump (adeABC) and quorum sensing (luxI, luxR) genes in clinical isolates of Acinetobacter baumannii.
  publication-title: APMIS
  doi: 10.1111/apm.12455
  contributor:
    fullname: Modarresi
– volume: 54
  start-page: 593
  year: 2016
  ident: B18
  article-title: Utility of whole-genome sequencing in characterizing Acinetobacter epidemiology and analyzing hospital outbreaks.
  publication-title: J. Clin. Microbiol.
  doi: 10.1128/jcm.01818-15
  contributor:
    fullname: Fitzpatrick
– volume: 50
  start-page: 2982
  year: 2012
  ident: B30
  article-title: Recurrent bacteremia caused by the Acinetobacter calcoaceticus-Acinetobacter baumannii complex.
  publication-title: J. Clin. Microbiol.
  doi: 10.1128/jcm.01194-12
  contributor:
    fullname: Lai
– volume: 3
  year: 2012
  ident: B53
  article-title: The Acinetobacter baumannii oxymoron: commensal hospital dweller turned pan-drug-resistant menace.
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2012.00148
  contributor:
    fullname: Roca
– volume: 16
  year: 2016
  ident: B26
  article-title: Characteristics of invasive Acinetobacter species isolates recovered in a pediatric academic center.
  publication-title: BMC Infect. Dis.
  doi: 10.1186/s12879-016-1678-9
  contributor:
    fullname: Jain
– volume: 76
  start-page: 392
  year: 2013
  ident: B61
  article-title: Acinetobacter pittii and Acinetobacter nosocomialis among clinical isolates of the Acinetobacter calcoaceticus-baumannii complex in Sichuan, China.
  publication-title: Diagn. Microbiol. Infect. Dis.
  doi: 10.1016/j.diagmicrobio.2013.03.020
  contributor:
    fullname: Wang
– volume: 65
  start-page: 233
  ident: B23
  article-title: Global spread of carbapenem-resistant Acinetobacter baumannii.
  publication-title: J. Antimicrob. Chemother.
  doi: 10.1093/jac/dkp428
  contributor:
    fullname: Higgins
– volume: 66
  start-page: 738
  year: 2011
  ident: B28
  article-title: Species identification and molecular characterization of Acinetobacter spp. blood culture isolates from Norway.
  publication-title: J. Antimicrob. Chemother.
  doi: 10.1093/jac/dkq521
  contributor:
    fullname: Karah
– volume: 62
  start-page: e1514
  year: 2018
  ident: B11
  article-title: Effect of incubation temperature on antibiotic resistance and virulence factors of Acinetobacter baumannii ATCC 17978.
  publication-title: Antimicrob. Agents Chemother.
  doi: 10.1128/aac.01514-17
  contributor:
    fullname: De Silva
– volume: 5
  year: 2010
  ident: B12
  article-title: The population structure of Acinetobacter baumannii: expanding multiresistant clones from an ancestral susceptible genetic pool.
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0010034
  contributor:
    fullname: Diancourt
– volume: 99
  start-page: 360
  year: 2018
  ident: B47
  article-title: Acinetobacter pittii isolated more frequently than Acinetobacter baumannii in blood cultures: the experience of a French hospital.
  publication-title: J. Hosp. Infect.
  doi: 10.1016/j.jhin.2018.03.019
  contributor:
    fullname: Pailhories
– volume: 58
  start-page: 936
  year: 2014
  ident: B51
  article-title: Identification of 50 class D beta-lactamases and 65 Acinetobacter-derived cephalosporinases in Acinetobacter spp.
  publication-title: Antimicrob. Agents Chemother.
  doi: 10.1128/aac.01261-13
  contributor:
    fullname: Perichon
– volume: 6
  start-page: 495
  year: 2011
  ident: B16
  article-title: Clinical impact and molecular basis of antimicrobial resistance in non-baumannii Acinetobacter.
  publication-title: Future Microbiol.
  doi: 10.2217/fmb.11.30
  contributor:
    fullname: Espinal
– volume: 64
  start-page: 282
  year: 2012
  ident: B62
  article-title: Nosocomial bloodstream infections due to Acinetobacter baumannii, Acinetobacter pittii and Acinetobacter nosocomialis in the United States.
  publication-title: J. Infect.
  doi: 10.1016/j.jinf.2011.12.008
  contributor:
    fullname: Wisplinghoff
– volume: 53
  start-page: 140
  year: 2008
  ident: B63
  article-title: Biofilm production by clinical strains of Acinetobacter baumannii isolated from patients hospitalized in two tertiary care hospitals.
  publication-title: FEMS Immunol. Med. Microbiol.
  doi: 10.1111/j.1574-695X.2008.00403.x
  contributor:
    fullname: Wroblewska
– volume: 68
  start-page: 1576
  year: 2013
  ident: B3
  article-title: Validation of carbapenemase and extended-spectrum beta-lactamase multiplex endpoint PCR assays according to ISO 15189.
  publication-title: J. Antimicrob. Chemother.
  doi: 10.1093/jac/dkt065
  contributor:
    fullname: Bogaerts
– volume: 5
  year: 2010
  ident: B10
  article-title: Do biofilm formation and interactions with human cells explain the clinical success of Acinetobacter baumannii?
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0010732
  contributor:
    fullname: de Breij
– volume: 13
  year: 2013
  ident: B20
  article-title: Virulence-related traits of epidemic Acinetobacter baumannii strains belonging to the international clonal lineages I-III and to the emerging genotypes ST25 and ST78.
  publication-title: BMC Infect. Dis.
  doi: 10.1186/1471-2334-13-282
  contributor:
    fullname: Giannouli
– volume: 19
  start-page: 737
  year: 2013
  ident: B56
  article-title: Molecular epidemiology of Acinetobacter baumannii and Acinetobacter nosocomialis in Germany over a 5-year period (2005-2009).
  publication-title: Clin. Microbiol. Infect.
  doi: 10.1111/1469-0691.12026
  contributor:
    fullname: Schleicher
– volume: 292
  start-page: 19628
  year: 2017
  ident: B29
  article-title: Defining the interaction of the protease CpaA with its type II secretion chaperone CpaB and its contribution to virulence in Acinetobacter species.
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M117.808394
  contributor:
    fullname: Kinsella
– volume: 52
  start-page: 352
  year: 2011
  ident: B7
  article-title: Influence of genospecies of Acinetobacter baumannii complex on clinical outcomes of patients with acinetobacter bacteremia.
  publication-title: Clin. Infect. Dis.
  doi: 10.1093/cid/ciq154
  contributor:
    fullname: Chuang
– volume: 65
  start-page: 228
  year: 2010
  ident: B52
  article-title: Novel role of Acinetobacter baumannii RND efflux transporters in mediating decreased susceptibility to biocides.
  publication-title: J. Antimicrob. Chemother.
  doi: 10.1093/jac/dkp427
  contributor:
    fullname: Rajamohan
– volume: 3
  start-page: 704
  year: 2014
  ident: B19
  article-title: Iron and Acinetobacter baumannii biofilm formation.
  publication-title: Pathogens
  doi: 10.3390/pathogens3030704
  contributor:
    fullname: Gentile
– volume: 302
  start-page: 117
  year: 2012
  ident: B58
  article-title: Surface-associated motility, a common trait of clinical isolates of Acinetobacter baumannii, depends on 1,3-diaminopropane.
  publication-title: Int. J. Med. Microbiol.
  doi: 10.1016/j.ijmm.2012.03.003
  contributor:
    fullname: Skiebe
– volume: 55
  start-page: 477
  year: 2006
  ident: B6
  article-title: Presence of active efflux systems AdeABC, AdeDE and AdeXYZ in different Acinetobacter genomic DNA groups.
  publication-title: J. Med. Microbiol.
  doi: 10.1099/jmm.0.46433-0
  contributor:
    fullname: Chu
– volume: 59
  start-page: 6657
  year: 2015
  ident: B14
  article-title: Identification of NDM-1 in a putatively novel Acinetobacter species (“NB14”) closely related to Acinetobacter pittii.
  publication-title: Antimicrob. Agents Chemother.
  doi: 10.1128/aac.01455-15
  contributor:
    fullname: Espinal
– volume: 60
  start-page: 483
  year: 2007
  ident: B44
  article-title: Relationship between the AdeABC efflux system gene content, netilmicin susceptibility and multidrug resistance in a genotypically diverse collection of Acinetobacter baumannii strains.
  publication-title: J. Antimicrob. Chemother.
  doi: 10.1093/jac/dkm231
  contributor:
    fullname: Nemec
– volume: 50
  start-page: 434
  year: 2012
  ident: B39
  article-title: Extracellular stress and lipopolysaccharide modulate Acinetobacter baumannii surface-associated motility.
  publication-title: J. Microbiol.
  doi: 10.1007/s12275-012-1555-1
  contributor:
    fullname: McQueary
– volume: 43
  start-page: 4328
  year: 2005
  ident: B57
  article-title: Standardization and interlaboratory reproducibility assessment of pulsed-field gel electrophoresis-generated fingerprints of Acinetobacter baumannii.
  publication-title: J. Clin. Microbiol.
  doi: 10.1128/jcm.43.9.4328-4335.2005
  contributor:
    fullname: Seifert
– volume: 7
  year: 2016
  ident: B1
  article-title: Reservoirs of non-baumannii Acinetobacter species.
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2016.00049
  contributor:
    fullname: Al Atrouni
– volume: 30
  start-page: 2725
  year: 2013
  ident: B59
  article-title: MEGA6: molecular evolutionary genetics analysis version 6.0.
  publication-title: Mol. Biol. Evol.
  doi: 10.1093/molbev/mst197
  contributor:
    fullname: Tamura
– start-page: 4105
  year: 2016
  ident: B9
  article-title: Acinetobacter dijkshoorniae sp. nov., a member of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex mainly recovered from clinical samples in different countries. Int. J. Syst. Evol. Microbiol.
  doi: 10.1099/ijsem.0.001318
  contributor:
    fullname: Cosgaya
– volume: 58
  start-page: 4172
  year: 2014
  ident: B8
  article-title: Clinical outcomes of hospital-acquired infection with Acinetobacter nosocomialis and Acinetobacter pittii.
  publication-title: Antimicrob. Agents Chemother.
  doi: 10.1128/aac.02992-14
  contributor:
    fullname: Chusri
– volume: 15
  start-page: 79
  year: 2012
  ident: B2
  article-title: Identification of virulence markers in clinically relevant strains of Acinetobacter genospecies.
  publication-title: Int. Microbiol.
  doi: 10.2436/20.1501.01.161
  contributor:
    fullname: Bitrian
– volume: 39
  start-page: 81
  year: 2012
  ident: B48
  article-title: Characteristics of carbapenem-resistant Acinetobacter spp. other than Acinetobacter baumannii in South Korea.
  publication-title: Int. J. Antimicrob. Agents
  doi: 10.1016/j.ijantimicag.2011.08.006
  contributor:
    fullname: Park
– volume: 19
  start-page: 640
  year: 2013
  ident: B35
  article-title: Bacteremic nosocomial pneumonia caused by Acinetobacter baumannii and Acinetobacter nosocomialis: a single or two distinct clinical entities?
  publication-title: Clin. Microbiol. Infect.
  doi: 10.1111/j.1469-0691.2012.03988.x
  contributor:
    fullname: Lee
– volume: 18
  start-page: 268
  year: 2012
  ident: B37
  article-title: Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance.
  publication-title: Clin. Microbiol. Infect.
  doi: 10.1111/j.1469-0691.2011.03570.x
  contributor:
    fullname: Magiorakos
– volume: 26
  start-page: 171
  year: 2016
  ident: B41
  article-title: Comparison of the virulence-associated phenotypes of five species of Acinetobacter baumannii complex.
  publication-title: J. Microbiol. Biotechnol.
  doi: 10.4014/jmb.1507.07076
  contributor:
    fullname: Na
– volume: 33
  start-page: 11
  year: 1995
  ident: B60
  article-title: Identification of Acinetobacter genomic species by amplified ribosomal DNA restriction analysis.
  publication-title: J. Clin. Microbiol.
  doi: 10.1128/JCM.33.1.11-15.1995
  contributor:
    fullname: Vaneechoutte
– volume: 58
  start-page: 152
  year: 2012
  ident: B25
  article-title: Study of the correlation of imipenem resistance with efflux pumps AdeABC, AdeIJK, AdeDE and AbeM in clinical isolates of Acinetobacter baumannii.
  publication-title: Chemotherapy
  doi: 10.1159/000335599
  contributor:
    fullname: Hou
– volume: 16
  start-page: 91
  year: 2018
  ident: B22
  article-title: Uncovering the mechanisms of Acinetobacter baumannii virulence.
  publication-title: Nat. Rev. Microbiol.
  doi: 10.1038/nrmicro.2017.148
  contributor:
    fullname: Harding
SSID ssj0000402000
Score 2.353831
Snippet The increased use of molecular identification methods and mass spectrometry has revealed that Acinetobacter spp. of the A. baumannii (Ab) group other than A....
The increased use of molecular identification methods and mass spectrometry has revealed that Acinetobacter spp. of the A. baumannii (Ab) group other than A....
SourceID doaj
pubmedcentral
csuc
proquest
crossref
SourceType Open Website
Open Access Repository
Aggregation Database
StartPage 2429
SubjectTerms Acinetobacter
Bacteris gramnegatius
biofilm formation
C. elegans
Drug resistance
efflux pumps
Gram-negative bacteria
Microbiology
multi-drug resistance
Resistència als medicaments
virulence
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1La9wwEBZhoZBLadKUbvNAhR6SglvLkmX5uC0JaaEhh6bkJjSyRN2DHXa9gf77zMi7YX3qpQcfJNmWmBlpZqSZT4x9cL5oohTomxQAmRLCZxB0zDzl63kRjUiINz9u9PWd-n5f3u9c9UUxYSM88Ei4z1E3pEIqBV6p2kWIpTO11yaCU6Ea03xFueNMpTWY3KI8H88l0QurkU2tBwrlqj-RWqonemjmV2u_Qe2fmJrTQMkdzXP1ir3cmIx8MQ71gO2F7pC9GC-R_Pua_fnW8cd2WPbcdQ1vqfDY81_tcp3yifhtP1BEEP6hjxzNPX45ZlwOPN09H1bb-gWdsdP8JvxmDo6297u25ecLuOBpj-qI3V1d_vx6nW1uUMi8MmLIyiiDMEHGGB3UwVSukKBybNSouE1N5lkVgdKIggBV-NgYqSqcp3XwAJV8w2Zd34W3jGtBKyGANCV-7gTERinvCZwilkHqObvY0tM-jEAZFh0Mor1NtLdEe5toP2cfieAW1_Sw9G6whHH9XKCnyKvCSq1Vmc_ZF2LL80_p3VSBUmI3UmL_JSVz9n7LVIvzhw5FXBf69cqifSt1iXYvdlRNuD3pcdrStb8TErc2hdBGvvsfQzxm-0Qh0ouFOmGzYbkOp2jwDHCWZPsJ4r0BqQ
  priority: 102
  providerName: Directory of Open Access Journals
– databaseName: Scholars Portal Open Access Journals
  dbid: M48
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3di9QwEA-6Ivgi5xeuehLBB0_osflomj4cxyp3nMKJD67sW8ikyVmRVrvdw_vvzaTd08I9-NCHNG0CM5nMbzKZGUJeW8erIFi0TThAJhlzGXgVMofxeo4FzVLGm_NP6mwlP67z9d_w6JGAmxtNO6wntep-HP7-dXUcBf4ILc6obyMHagd4S6s8RI1T3iZ3uBQS1_v5CPbTvoymUopJYUqhO4CvB7_ljYNM9NTMbbZuzOo_gaLTi5T_aKbTPXJ_hJR0OayBB-SWbx6Su0ORyatH5PuHhl7WfddS21S0xsZlS7_W3TbFG9HPbY83huIIbaARDtKTISKzp6k2vd_s3i_RB4_yj_mdKVg8_m_qmr5ZwgFNZ1iPyer05Mv7s2yssJA5qVmf5UF4pr0IIVgovS4sFyAXsVNFxa5LhG9FAAwz8gwkd6HSQhZRjkvvAArxhMyatvFPCVUMd0oAofP4u2UQKimdw-QVIfdCzcnBjp7m55BIw0QDBGlvEu0N0t4k2s_JWyS4iXu-75ztDebAvm7gwxcFNyKyMV_MyTtky_Wg-G160XYXZhQ_E1SFQKSQ4KQsbYCQW106pQNY6Qs9J692TDVRvtBpYhvfbjcm4l-h8oiL40TFhNuTGac9Tf0tZepWmjOlxbP_GP05uYcEQLXI5Qsy67ut3494p4eXaRn_AZSg_6I
  priority: 102
  providerName: Scholars Portal
Title In vitro and in vivo Virulence Potential of the Emergent Species of the Acinetobacter baumannii (Ab) Group
URI https://search.proquest.com/docview/2313651610
https://recercat.cat/handle/2072/366450
https://pubmed.ncbi.nlm.nih.gov/PMC6821683
https://doaj.org/article/f6d661474bc449afbf5a89c68fba4e78
Volume 10
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3di9wgEJe7hUJfSj_p9uOw0IdeIbsxGmMet8ddr4Ut99Ar-yZqtE3pJUc2e9D_vjNmc2xe-xBBTTQ4o_MbnRkJeW9cVgXOQDfJrE0EYy6xXobEob-eY0GxGPFm_U1eXouvm3xzRPLRFyYa7TtbL5o_N4um_hVtK29v3HK0E1terc-kyphUfHlMjgvOD1T0uPyiRpSmw5EkKGAlUKh2Fq24ygVKJAwUClIzVSW6tR1Io5nb7tw-dv8EcE7NJQ_kz8Vj8mgPHOlq-MEn5Mg3T8mD4SrJv8_I7y8Nvav7rqWmqWiNmbuW_qi7XfQqoldtj3ZB0EIbKIA-ej74XfY03kDvt2P5Ck_acZZjFGdqDW7yN3VNP6zsKY07Vc_J9cX597PLZH-PQuKEYn2SB-6Z8jyEYGzpVWEybkUKlRLEtyoRpBXBojORZ1ZkLlSKiwJma-mdtQV_QWZN2_iXhEqG66G1XOXwuWE2VEI4hyEqQu65nJPTcTz17RAuQ4OagWTQkQwayaAjGebkIw64hpXdd870GiNd32fwydIi01xKkadz8gnJct8ovhsL2u6n3vOGDrJCuFEI64QoTbAhN6p0UgVrhC_UnLwbiaphFuHRiGl8u9tqQLlc5oB-oaNiQu1Jj9MaYM8Yj3vPjq_--8vX5GGGaCGVSSbekFnf7fxbwDq9PYl7BJB-3jBI10KdRG7_B6XVA9s
link.rule.ids 230,315,733,786,790,870,891,2115,24346,27957,27958,53827,53829
linkProvider National Library of Medicine
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3Pb9MwFLZGEYILvxHlp5E4MKS0cew4zrFMmzpYpx22aTfLz7UhwJKpTSfBX4-f00wtNzjkkDiJk3y23_fi9z4T8t7YbO45C75JBpAIxmwCTvrEYr6eZV6xqHgzO5bTM_H5Ir_YIXmfCxOD9i1Uo_rn5aiuvsXYyqtLO-7jxMYnsz2pMiYVH98it0N_zYoNJz0OwOgTpWk3KRlcsDJgVFnAOK5yhDYJpUKD3UxViYltG_ZoYJcru1bv36Kc2wGTGxbo4AE575-9Czz5MVq1MLK__5J1_OeXe0jurzkpnXTFj8iOqx-TO90qlb-ekO-HNb2u2kVDTT2nFe5cN_S8WqxiwhI9aVoMOQp3aDwNfJLudymdLY2L27tlf3yCk_g4gKBANAWD8wd1VdEPE9il8SfYU3J2sH-6N03WSzQkVijWJrnnjinHvfcGSqcKk3EQaSiUgRmoEvlf4QHzlBwDkVk_V1wUYSAonQUo-DMyqJvaPSdUMhxqAbjKw-WGgZ8LYS2qX_jccTkkuz1Q-qpT4tDBg0F8dcRXI7464jskHxFJHYyGW1jTahTRvtnBLUuLTHMpRZ4OySfE--ameG480Cy-6jUy2ss5MplCgBWiNB58blRppfJghCvUkLzrW4sOHRRnXUztmtVSBwLNZR6Idaio2GpGWzVul4TGEaW-143hxX9f-ZbcnZ7OjvTR4fGXl-QefiK0vJl4RQbtYuVeB0rVwpvYgf4AnKYjEg
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lj9MwELagCMSFN6I8jcSBRUobx47jHMuy1S6wqx5YtOJieRwbAmxStelK8OvxOO2q5biHHPKw8_hszzfxzGdC3hibVZ6z4JtkAIlgzCbgpE8s5utZ5hWLijfHJ_LwVHw8y8-2lvqKQfsW6lHz-3zU1D9ibOX83I43cWLj2fG-VBmTio_nlR9fJzdCn83KLUc9DsLoF6VpPzEZ3LAy4FRbwFiucoR2CeVCg-1MVYnJbVs2aWCXK7tW8N-hnbtBk1tWaHqXfNs8fx988mu06mBk__4n7XilF7xH7qy5KZ30l9wn11zzgNzsV6v885D8PGroRd0tWmqaita4c9HSr_ViFROX6KztMPQo1NB6GnglPehTOzsaF7l3y83xCU7m40CCQtEUDM4jNHVN305gj8afYY_I6fTgy_5hsl6qIbFCsS7JPXdMOe69N1A6VZiMg0jDSRkYgiqRBxYeMF_JMRCZ9ZXioggDQuksQMEfk0HTNu4JoZLhkAvAVR6KGwa-EsJaVMHwueNySPY2YOl5r8ihgyeDGOuIsUaMdcR4SN4hmjoYD7ewptMopn25g1uWFpnmUoo8HZL3iPllpXhtPNAuvus1OtrLChlNIcAKURoPPjeqtFJ5MMIVakheb1qMDh0VZ19M49rVUgcizWUeCHa4UbHTlHbuuHsmNJAo-b1uEE-vXPIVuTX7MNWfj04-PSO38QuhAc7EczLoFiv3IjCrDl7GPvQPo5glkg
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=In+vitro+and+in+vivo+Virulence+Potential+of+the+Emergent+Species+of+the+Acinetobacter+baumannii+%28Ab%29+Group&rft.jtitle=Frontiers+in+microbiology&rft.au=Cosgaya%2C+Clara&rft.au=Ratia%2C+Carlos&rft.au=Mar%C3%AD-Almirall%2C+Marta&rft.au=Rubio%2C+Laia&rft.date=2019-10-24&rft.issn=1664-302X&rft.eissn=1664-302X&rft.volume=10&rft.spage=2429&rft.epage=2429&rft_id=info:doi/10.3389%2Ffmicb.2019.02429&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1664-302X&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1664-302X&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1664-302X&client=summon