Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis - Flex, E.; Jaiswal, M.; Pantaleoni, F.; Martinelli, S.; Strullu, M.; Fansa, E. K.; Caye, A.; De Luca, A.; Lepri, F.; Dvorsky, R.; Pannone, L.; Paolacci, S.; et al. (Human molecular genetics, 2014)
Keywords: Animals; Caenorhabditis elegans; Carcinogenesis - genetics; Cohort Studies; Extracellular Signal-Regulated MAP Kinases - metabolism; Humans; Leukemia, Myeloid, Acute - genetics; Leukemia, Myelomonocytic, Juvenile - genetics; MAP Kinase Kinase Kinases - metabolism; Mutation - physiology; Noonan Syndrome - genetics; Oncogene Protein v-akt - metabolism; Phenotype; ras Proteins - chemistry; ras Proteins - genetics; ras Proteins - metabolism; Signal Transduction - genetics