A Monoclonal-Monoclonal Antibody Based Capture ELISA for Abrin

• Published in: Toxins Vol. 9; no. 10; p. 328
• Main Authors: Tam, Christina C, Cheng, Luisa W, He, Xiaohua, Merrill, Paul, Hodge, David, Stanker, Larry H
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 18.10.2017; MDPI
• Subjects: abrin; abrus precatorius; Chains; Contamination; Cross-reactivity; ELISA; Enzyme-linked immunosorbent assay; Immunoglobulins; Monoclonal antibodies; Proteins; Reagents; ribosome-inactivating protein; Sensors; Toxicity; Toxins; abrin; abrus precatorius; ribosome-inactivating protein; ELISA; monoclonal antibodies

Abrin, one of the most highly potent toxins in the world, is derived from the plant, . Because of its high toxicity, it poses potential bioterror risks. Therefore, a need exists for new reagents and technologies that would be able to rapidly detect abrin contamination as well as lead to new therapeu...