Success of Immunosuppressive Treatments in Patients with Chronic Graft-versus-Host Disease

• Published in: Biology of blood and marrow transplantation Vol. 24; no. 3; pp. 555 - 562
• Main Authors: Lee, Stephanie J., Nguyen, Tam D., Onstad, Lynn, Bar, Merav, Krakow, Elizabeth F., Salit, Rachel B., Carpenter, Paul A., Rodrigues, Morgani, Hall, A. Marcie, Storer, Barry E., Martin, Paul J., Flowers, Mary E.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2018
• Subjects: Allogeneic hematopoietic cell transplantation; Chronic graft-versus-host disease; Immunosuppressive treatment; Chronic graft-versus-host disease; Allogeneic hematopoietic cell transplantation; Immunosuppressive treatment

•After stopping therapy for chronic GVHD, half restarted after a median of 3.4 months.•After 5.6 years, one-third each were still on IST, alive off IST, or dead/relapsed. Moderate to severe chronic graft-versus-host disease (GVHD) is treated with potent immunosuppressive therapy (IST) to modulate th...